Karolinska Institute, Sweden invites online Application for number of Fully Funded PhD Degree at various Departments. We are providing a list of Fully Funded PhD Programs available at Karolinska Institute, Sweden.
Eligible candidate may Apply as soon as possible.
(01) PhD Degree – Fully Funded
PhD position summary/title: 1-2 doctoral (PhD) student positions with focus on single-cell/spatial omics and molecular mechanisms underlying multiple sclerosis
Our research group has performed single-cell/spatial omics studies, identifying for instance several cell states within the oligodendrocyte lineage in development and disease (Science 2016, Dev Cell 2018, Nature Medicine 2018, Nature 2019, Nature Biotechnology 2021, 2022, Neuron 2022, Nature 2023, among others). Our recent findings suggest that oligodendrocyte lineage cells might present other functional properties than previously thought, transitioning for instance to disease-associated states. In addition, our results also suggest that single nucleotide polymorphisms (SNPs) associated with multiple sclerosis susceptibility might be operational in oligodendrocyte lineage cells. The PhD student(s) project(s) will focus on the development and application of single-cell/spatial omics technologies, and/or investigate the molecular mechanisms operational in disease-associated oligodendrocytes and underlying the function of these SNPs. The successful candidate(s) will be integrated in a multidisciplinary team comprising computational, molecular and cellular biologists and neuroimmunologists
Deadline : 15.Sep.2023
(02) PhD Degree – Fully Funded
PhD position summary/title: PhD student – Single cell analysis of the developing and aging inner ear
We are seeking a highly motivated student with a strong bioinformatics background who is interested in using single-cell computational tools to better understand the complexity of cell types in various conditions, their potential interactions, and biological impacts in a whole organ. The candidate’s primary responsibility will be to establish pipelines for analyzing gene expression data from single-cell RNA-sequencing (Smartseq3xpress and 10X), spatial transcriptomics, and other platforms, including chromatin accessibility sequencing (ATAC-seq and multi-omics). The candidate will analyze cell-type-specific aging clock, GRNs, loss of gene-to-gene transcriptional coordination, and transcriptome imbalance, among other things, to make significant advances in the genetic regulation of complex organ emergence and senescence in mammals. The doctoral student will be employed on a funded studentship for a 4-year full-time position. The position will be based in the Lallemend lab at the Karolinska Institute in Stockholm, Sweden, with internships in the laboratory of Prof. Matthew W. Kelley at NIH. For more information on Lallemend’s lab, please visit https://ki.se/en/neuro/lallemend-lab, and for information on Kelley’s lab at NIH, visit https://www.nidcd.nih.gov/about/staff/matthew-w-kelley-phd.
Deadline : 22.Aug.2023
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(03) PhD Degree – Fully Funded
PhD position summary/title: Doctoral student in Machine learning applied to radiological imaging
AI is a potent tool for risk prediction, detection, lesion segmentation, treatment planning, and response for breast cancer in particular. The performance of such tools heavily depends on the data used for development. Today, many research groups and commercial vendors are formulating approaches – model- and data-centric – to provide state-of-the-art models and diagnostic-assistive and precision medicine solutions. Our team has already been involved in the development of risk prediction and cancer detection models. At the same time, we have also established and currently run a national platform for external evaluation of breast cancer detection algorithms in mammograms.
Deadline : 18.Aug.2023
(04) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Medical Education
The doctoral student project will explore the role of patients in the learning of medical students. The aim is to better understand how students learn from and together with patients and how this learning can be supported and developed. The project adopts a qualitative approach, and data will be collected through observational studies and interviews with medical students, supervisors, and patients. By gaining a deeper understanding of the patient’s role in the clinical learning context, we hope to improve the education of future doctors and simultaneously enhance patients’ experiences of healthcare. The project is based on socio-cultural theories and will apply phenomenography and activity theory as the primary research methodologies. The doctoral project is carried out within the framework of the Research School of Medical Education, which is a collaboration between Linköping University, Karolinska Institutet (KI), and Stockholm University. The Graduate School offers courses, seminars, and annual retreats Forskarskola i medicinsk pedagogik – Linköpings universitet (liu.se).
Deadline : 13.Aug.2023
(05) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in psychiatric epidemiology
The overall aim of the project is to characterize patterns, risk factors, treatment and pathways to labor market marginalization in individuals with diagnosed depressive or anxiety disorder. The studies build on register data and the doctoral student will learn to apply advanced statistical methods and epidemiological design. The student will predominantly review the literature, prepare working data files, run statistical analyses and write manuscripts. In this process, the doctoral student will be supervised by Ellenor Mittendorfer-Rutz (main supervisor, Professor of Insurance medicine), Katalin Gemes (Assistant Professor), and Magnus Helgesson (Assistant Professor).
Deadline : 13.Aug.2023
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(06) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) position in genetics
The doctoral student will perform analysis of medical genetics, archaic DNA, population-scale biobanks, and conduct experimental research. This includes challenging tasks in computational biology, bioinformatics, and wet-lab work including molecular biology and pharmacology. Overall, the project strives to leverage combined insights in genetics with medical knowledge to gain insights of pathophysiological and pharmacological relevance.
Deadline : 11.Aug.2023
(07) PhD Degree – Fully Funded
PhD position summary/title: PhD position in functional epigenetics in monocytes and atherosclerosis
The student will develop molecular techniques to investigate the functionality of regulatory chromatin regions in metabolic and immune cells. He/she will also use these techniques to study how dyslipidaemia controls the disease-related chromatin remodelling events in the monocytes.
Deadline : 09.Aug.2023
(08) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in experimental psychology/social neuroscience with focus on social learning and cultural evolution
The goal of the project (PI Björn Lindström) is to develop a new framework for understanding the psychological, neural, and computational mechanisms of social learning, social transmission, and cultural evolution. The doctoral student will lead a new project that will investigate the social learning mechanisms involved in human cultural evolution. Using sophisticated behavioral methods, computational modeling, and brain imaging, this project will seek to identify the computational and neural basis of the (reinforcement) learning mechanisms that allow for human cultural evolution. The doctoral student will also have the opportunity to develop their own ideas within the areas of social learning and cultural evolution. They will be responsible for setting up experiments, analyzing data, and writing scientific articles. The research group has access to two state-of-the-art 3-Tesla MRI scanners at the Karolinska Institutet and Stockholm University Brain Imaging Center (SUBIC). As a doctoral student, you will have the chance to work in a successful and well-funded research group, collaborating with senior and junior researchers. The group also has collaborations with other research groups at the department and prominent international research groups, offering opportunities for international exchanges.
Deadline : 07.Aug.2023
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(09) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in endocrinology
The doctoral student will lead the literature review and the outlining of the analysis plan as well as data analysis and the writing of research papers within endocrinology.
Deadline : 06.Aug.2023
(10) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in immunology
The research project will characterize fundamental features of T cell biology and immunometabolism and uncover, for the first time, the role of atypical ubiquitination in T cells. Particularly, the Ph.D. student will use knockout strategies in cells and mice to investigate the role of a novel ubiquitin-related enzyme in the regulation of the responses and metabolism of T cells. For this, the student will use mainly gene-edited mice to perform diverse ex vivo and in vivo T-cell-based studies, disease models of cancer, asthma, and airway inflammation, as well as biochemical and proteomics approaches. In doing this project, the student will help illuminate the complexity and dynamics of the ubiquitin code, highlight the relevance of atypical ubiquitin chains in T-cell biology and immunity, as well as uncover molecular mechanisms involved in immune-mediated diseases that could serve for future targeted therapies. The project requires learning and applying diverse methodologies in which the group is specialized, including the use of knockout mice and in vivo models of immunity, CRISPR/Cas9 and shRNA gene-editing technologies, microscopy, FACS, histology, overexpression and immunoprecipitations, enzymatic assays, and seahorse flux metabolic studies. For this, the student will take advantage of the common lab set-ups, knowledge, and support, but will work independently. The successful applicant will acquire basic as well as specialized knowledge and understanding in T cell biology, disease modeling, posttranslational modifications, and gene regulation. The project offers the possibility to gain substantial training in modern biomedical research and complementary skills to promote both professional and personal development.
Deadline : 06.Aug.2023
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About The Karolinska Institute, Sweden – Official Website
The Karolinska Institute sometimes known as the (Royal) Caroline Institute in English is a research-led medical university in Solna within the Stockholm urban area of Sweden. The Nobel Assembly at the Karolinska Institute awards the Nobel Prize in Physiology or Medicine. The assembly consists of fifty professors from various medical disciplines at the university. The current rector of Karolinska Institute is Ole Petter Ottersen, who took office in August 2017.
The Karolinska Institute was founded in 1810 on the island of Kungsholmen on the west side of Stockholm; the main campus was relocated decades later to Solna, just outside Stockholm. A second campus was established more recently in Flemingsberg, Huddinge, south of Stockholm.
The Karolinska Institute is Sweden’s third oldest medical school, after Uppsala University (founded in 1477) and Lund University (founded in 1666). It is one of Sweden’s largest centres for training and research, accounting for 30% of the medical training and more than 40% of all academic medical and life science research conducted in Sweden.
The Karolinska University Hospital, located in Solna and Huddinge, is associated with the university as a research and teaching hospital. Together they form an academic health science centre. While most of the medical programs are taught in Swedish, the bulk of the PhD projects are conducted in English. The institute’s name is a reference to the Caroleans.
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