11 Postdoctoral Fellowship at University of British Columbia, Canada

A postdoc fellowship position is available in Dr. Xuesen Dong’s lab (http://donglab.ca). Our research focuses on the mechanisms of therapy-resistant prostate cancers and the development of therapeutics to manage the disease (representative publications PMID: 32634132, 30910347, 27180064, 31819165). Ongoing projects include

1. deciphering cancer stem cell signal pathways to regulate neuroendocrine prostate cancers and
2. alternative RNA to regulate therapy-resistant prostate cancer progression.
3. drug development targeting Lin28 and TOP2

We are looking for multiple candidates to expand the existing projects to understand how Lin28 regulates stem cell networks to counteract therapy-induced stress and apply computer-aided drug design to develop Lin28 inhibitors. Candidates with animal handling, lentiviral manipulations, or ChIP-seq backgrounds are welcome. 

An early change in cardiac metabolism is considered a major culprit for diabetic cardiomyopathy (DCM). The metabolic shift in the diabetic heart includes reduced glucose consumption, and a switch to utilize more fatty acids for energy, a destructive adaptation implicated in cell death and DCM. The Rodrigues Lab is interested in examining the mechanism of how fatty acids are provided to the heart and how an excess can lead to cardiac disease. Appreciating this mechanism should allow the identification of novel targets for therapeutic intervention to prevent heart failure during diabetes.

A full-time postdoctoral position is available in the laboratory of Dr. Brian Rodrigues, Faculty of Pharmaceutical Sciences, UBC. The individual will be responsible for the design and execution of research projects involved in investigating the switch in cardiac energy supply (from glucose to fatty acid) following diabetes. Applicants must therefore have extensive knowledge and experience in various lab techniques to investigate cardiac metabolism, using animal modeling, cell culture (primary endothelial cells and cardiomyocyte isolation), molecular biology, and biochemistry.

Applicants should have a PhD in pharmacology, biochemistry, or a related field with relevant experience. You will be expected to take the lead role in your projects, to publish manuscripts as a first author, and to present your projects and data at lab meetings, as well as local and international meetings. A high level of participation in a collaborative team setting is required, with a high level of self-motivation, excellent time management skills, ability to demonstrate creativity and sound judgment. Exemplary interpersonal and communication skills are preferred as the candidate is expected to work closely with graduate students. The candidate should demonstrate strong writing skills to ensure writing of quality scientific publications and grant applications. Preference will be given to those with a strong publication record. We are well-funded by our grants, and are looking for a dynamic and diligent addition to our group. The expected salary range for this position is $50,000 to $60,000 per year.

Please send a CV, a description of your research experience and interests, and the contact information of two references to: [email protected] (www.rodrigueslab.ca). The position will remain open until filled. Preliminary interviews will be conducted over Zoom. Only those under consideration will be contacted.

Fluid biomarkers can provide a detailed picture of neurological health and disease using relatively low-cost, accessible, objective, and scalable tools. There has been a rapid expanse of research into candidate blood-based biomarkers that show utility for the diagnosis and prognosis of neurological conditions. This position will focus on the statistical analysis for multiple projects involving large scale databases from various cohorts, including but not limited to traumatic or hypoxic brain injury, spinal cord injury, Alzheimer’s disease and related dementias, Multiple Sclerosis and healthy aging. The postdoctoral fellow will oversee their own individual project, to be developed in collaboration between the supervisor and a successful candidate. They will also provide guidance to lab members for other projects.

We have an outstanding opportunity for a Postdoctoral Research Associate at the Department of Radiology – University of British Columbia to engage in a closely collaborative research and development project with our industry partner, Torus Biomedical Solutions. The goal of this project is to develop a software solution that facilitates automatic image-based measurements within an existing intraoperative assessment product. The postdoctoral candidate will have the support, guidance, and supervision from the engineering team at the company led by Dr. Shahram Amiri as well as Dr. ilker Hacihaliloglu assistant professor at the Department of Radiology – University of British Columbia.

As a Postdoctoral Research Fellow, you’ll play a pivotal role in leading and contributing to the development of a machine learning approach to automate intraoperative X-ray-based measurements in orthopedic surgery. Your tasks will include establishing a pipeline for generating synthetic fluoroscopic images, conducting a thorough review of cutting-edge techniques, and designing and testing deep learning neural networks for bone segmentation and landmark annotation. You’ll also evaluate system performance in both simulated and real surgical environments. Working closely with a diverse team of engineers, researchers, and surgeons, your contributions can seamlessly integrate into an existing commercial product. Furthermore, your research findings will be submitted for publication in peer-reviewed journals.

The MéridaLabs research group is seeking a highly qualified postdoctoral fellow with specialization in Computational Fluid Dynamics (CFD) to join our dynamic team and support the research and development and design activities on low-emission hydrogen production technology. The ideal candidate will have 5+ years of academic or industrial experience in CFD simulation, thermo-fluid mechanics, heat transfer, kinetic modeling, and multi-phase flow simulation. Having expertise in high-temperature hydrocarbon pyrolysis, corrosive environments, and a deep understanding of hydrogen systems is a merit. The CFD PDF will work with the VulcanX R&D team to design a new generation of prototype reactors to enhance the hydrogen yield and improve their thermal efficiency.

We are looking for a postdoctoral fellow who will strive to make a meaningful impact on child health by contributing to leading-edge research aimed at improving pain management.

In light of the current opioid crisis, there is increased urgency to balance both safety and effectiveness of opioid-based analgesics, while simultaneously limiting the use of opioids. Given the resulting hesitancy associated with prescribing opioids, we are likely undertreating pain in children. This can be particularly devastating in children with high burdens of pain, such as children with cancer, where ongoing pain can interfere with brain development, disrupt behaviour, and increase the risk of chronic pain.

Safe and effective pain management is influenced by individual genetic differences that dictate both how we feel pain and how we respond to specific analgesics. Using pharmacogenomics, the study of how genetic variability contributes to individual drug responses, we are identifying genetic factors that can help predict an individual’s need for, and subsequent response to, opioids. 

As part of the Loucks Pain Management Pharmacogenomics (PMP) Lab, and the multi-disciplinary Canadian Pharmacogenomics Network for Drug Safety (CPNDS), the candidate will work closely with clinicians, scientists and patients across Canada to advance a pipeline from genetic discoveries to predictive genetic testing to help select the safest and most effective pain management strategies for children based on their unique genetic signatures.

Professor Simon Donner and the Climate and Coastal Ecosystem Lab at the University of British Columbia in Vancouver, Canada are searching for a postdoctoral researcher to participate in interdisciplinary research on ocean extreme events and their effects on coastal ecosystems. The research group conducts work at the intersection of climate and marine science, and informs policy and management at national and international scales.

Coastal ecosystems are at the frontlines of climate change. Marine heatwaves attributed to human-caused climate change have caused mass mortality and phase shifts in coral reefs, kelp forests and other coastal ecosystems. In addition to other areas of climate science and policy research, our group studies the drivers of marine heatwaves and their effects on coral reef and kelp systems at the global scale using large-scale numerical modelling and data analysis, as well as via field research in the equatorial Pacific in collaboration with local partners (e.g., Republic of Kiribati, Galápagos Archipelago).

The postdoc will have the option to focus on one or more project(s) related to i) assessing multiple drivers of coral bleaching using a global database developed in the group; ii) drivers and effects of warm-season marine heatwaves in the central equatorial Pacific, iii) projecting the effect of compound climate extremes (temperature, oxygen, etc.) on coral and kelp systems. The position comes with opportunities to engage in climate policy and adaptation discussions, and for training in climate communication and engagement.

The Industrial and Multiphysics Laboratory at the University of British Columbia in Vancouver is looking for a postdoctoral research fellow (who has completed their PhD within the last five years at the time of appointment) to work on a newly industrial-funded 1-year postdoctoral research project. The successful PDF candidate will join a dynamic and multidisciplinary team under the supervision of Dr. Dana Grecov.

Dr. Grecov’s current research program focuses on studying complex fluids and their applications using numerical simulations and experimental methods. For more information about Industrial and Multiphysics Laboratory, please visit https://ibml.mech.ubc.ca/ and/or the LinkedIn page: https://www.linkedin.com/company/industrial-and-biological-multiphysics-laboratory/

As funders of this fellowship position, the scientists from the industrial partner will collaborate with and work alongside the successful candidate.

The successful applicants will be supervised by Director Dana Grecov and will work with the research team from the industrial partner. There are also opportunities to interact with various faculty in the Departments of Applied Science and Science at UBC. Therefore, a willingness to collaborate and mentor undergraduate and graduate students is advantageous.

The Industrial and Multiphysics Laboratory at the University of British Columbia in Vancouver is looking for a postdoctoral research fellow (who has completed their PhD within the last five years at the time of appointment) to work on a newly industrial-funded 1-year postdoctoral research project. The successful PDF candidate will join a dynamic and multidisciplinary team under the supervision of Dr. Dana Grecov.

Dr. Grecov’s current research program focuses on studying complex fluids and their applications using numerical simulations and experimental methods. For more information about Industrial and Multiphysics Laboratory, please visit https://ibml.mech.ubc.ca/ and/or the LinkedIn page: https://www.linkedin.com/company/industrial-and-biological-multiphysics-laboratory/

As funders of this fellowship position, the scientists from the industrial partner will collaborate with and work alongside the successful candidate.

This project seeks to develop and understand the manufacturing process for a hyaluronic acid-based product. Of particular interest are the insights of material chemical reactions, integrated, comprehensive results of dynamic chemical reaction with each step of material mixing properties through the analysis of chemical and physical characterization to enhance the robustness of the manufacturing process.

The successful applicants will be supervised by Director Dana Grecov and will work with the research team from the industrial partner. There are also opportunities to interact with various faculty in the Departments of Applied Science and Science at UBC. Therefore, a willingness to collaborate and mentor undergraduate and graduate students is advantageous.