19 Postdoctoral Fellowship at King’s College London, United Kingdom

The Department of Geography at King’s College London invites applications for a one-year (12 months), full-time (1.0 FTE) position as Postdoctoral Research Associate (PDRA). The post will be based in the research team of Professor Katherine Brickell at KCL’s Strand Campus in central London. Hybrid working can be accommodated.  

The PDRA will report to Professor Katherine Brickell (Department of Geography) and work closely with Dr Rosalie Warnock on their Leverhulme-funded research project “Sensory Lives: Neurodivergent Children and Families in Temporary Accommodation”. The PDRA will also liaise with research collaborators, including the Shared Health Foundation in Greater Manchester.

The research aims to better understand how homeless families with neurodivergent children experience Temporary Accommodation in the United Kingdom. Its goal is also to create spaces for their insights to be represented and registered in national discussions on the child homelessness crisis. See https://www.sensorylivesproject.org/about for more information.

Under the direction of Professor Katherine Brickell and Dr Rosalie Warnock, the PDRA will take on responsibilities for year-two of the 24-month Sensory Lives study. In year one (January-December 2025), the team developed playful, creative and inclusive methods for working with neurodivergent children and their families, and conducted the bulk of data collection. The primary role of the PDRA is to support the design and UK-wide tour of a playhouse tent which will communicate children’s experiences to diverse audiences. The playhouse tent looks to re-centre children’s perspectives in discussions of homelessness and communicate neurological difference more inclusively in research and policy. The PDRA will work with children and families to co-design the playhouse tent; travel with the tent and facilitate public engagement with it; and conduct qualitative data analysis (of engagement with the tent). Other responsibilities may include: organising national stakeholder interviews; engaging in policy-applied and/or academic writing; active participation and leadership in team-based workshops; travel and managing travel logistics; delivering academic presentations at conferences; and project talks to the public and policy stakeholders.

The Department of Informatics is looking to appoint a Research Associate to work in the area of cryptography.

The candidate will work alongside Prof. Martin Albrecht and other cryptographic researchers in the department on topics in lattice-based cryptography and related fields. The post is funded by an ERC/UKRI Frontier Research grant on investigating practical advanced post-quantum cryptography from lattices.

The applicant will work in the cryptography lab in the Cybersecurity group (CYS) in the department. The cryptography lab currently consists of Martin Albrecht, Ngoc Khanh Nguyen, Eamonn Postlethwaite, Benjamin Dowling as well as several students and postdocs.

Applicants should have already completed, or be close to completing, a PhD in a relevant discipline. Applicants should have an outstanding research track record in cryptography, ideally in lattice-based cryptography. Applicants should be able to demonstrate scientific creativity, research independence, and the ability to communicate their ideas effectively in written and verbal form.

We are seeking a highly motivated and talented Postdoctoral Research Associate to join Dr Joseph Burgoyne’s group at the Rayne Institute, St Thomas’ Hospital, part of King’s College London. Our research is dedicated to uncovering the fundamental mechanisms that maintain cardiovascular health and drive cardiovascular disease, with the ultimate aim of identifying and developing new therapeutic strategies. 

The successful candidate will lead research projects investigating novel strategies, discovered within our group, to combat heart failure. The work will integrate studies using isolated cell systems with advanced in vivo models, with a particular focus on characterising newly generated transgenic mouse lines. A key aspect of the work will be translational studies to evaluate new therapeutic strategies identified within our group, directly advancing our understanding of heart failure and accelerating the development of novel interventions.

Applicants must hold a PhD in a biological sciences discipline and demonstrate substantial experience working with animal models of cardiovascular disease, along with strong skills in cell and tissue biology techniques. Additional expertise in vessel myography or redox biology is highly desirable.

The Cobb group are looking for a passionate and creative scientist to join our team as a postdoctoral researcher in synthetic organic chemistry in the Department of Chemistry at the King’s College London on a project that seeks to design powerful modular asymmetric catalysts inspired by the helices seen in nature. 

The successful candidate will join the dynamic and collaborative research group of Professor André Cobb, working at the forefront of foldamer research and cutting-edge synthetic methodologies (for information about the group, please visit  http://www.cobbresearch.com) in collaboration with the group of Professor Craig Butts at the University of Bristol.

The postdoctoral researcher will be involved in designing and executing the synthesis of novel and innovative foldamer catalysts, and their application towards a variety of stereoselective processes, including organocatalytic and photocatalytic reactions. Applicants should have extensive experience in both small molecule (multi-step) synthesis and in solid phase peptide synthesis. Thus, the role could also be suitable for peptide and nucleic acid chemists who are interested in synthetic methodology.

The bacterial pathogen Klebsiella pneumoniae (Kp) is a major antibiotic-resistant pathogen responsible for high levels of mortality worldwide. Development of novel therapies and preventative vaccines is hampered by an incomplete understanding of the pathogenesis of Kp infection.

The extracellular polysaccharide capsule is a major Kp virulence determinant, but the molecular regulation of its expression during infection remains poorly understood. The Wanford group uses comparative genomics, molecular genetics and infection biology techniques to understand how Kp regulates expression of the capsule to transition between states of asymptomatic colonisation and invasive disease.

We are seeking a driven Postdoctoral Research Associate with a strong molecular microbiology skillset to lead a high impact project with two key aims: 

1. To define the mutational mechanisms regulating Kp capsule expression during infection
2. To identify functional consequences of capsule regulation on host-pathogen interactions at the molecular level

The successful candidate will combine cutting-edge microbiological, biochemical, molecular genetics, and comparative genomics-based approaches to develop their independent research project and will also be expected to collaborate more widely within the group, department, and with external collaborators. The candidate will be expected to contributed data and writing to peer reviewed manuscripts and will be supported for applications for independent fellowships towards the end of the post.

The bacterial pathogen Klebsiella pneumoniae (Kp) is a major antibiotic-resistant pathogen responsible for high levels of mortality worldwide. Development of novel therapies and preventative vaccines is hampered by an incomplete understanding of the pathogenesis of Kp infection. The extracellular polysaccharide capsule is a major Kp virulence determinant, but the molecular regulation of its expression during infection remains poorly understood. The Wanford group uses comparative genomics, molecular genetics and infection biology techniques to understand how Kp regulates expression of the capsule to transition between states of asymptomatic colonisation and invasive disease.

We are seeking a driven Research Associate with a strong infection biology skillset to lead a high impact project with two key aims: (1) defining bacterial factors required for systemic dissemination (2) characterising the regulation of capsule expression during transition between host compartments. 

The successful candidate will combine cutting-edge in vitro and in vivo infection models, and both microscopy and flow cytometry-based readouts of infection to develop their independent research project and will also be expected to collaborate more widely within the group, department, and with external collaborators. The candidate will be expected to contributed data and writing to peer reviewed manuscripts and will be supported for applications for independent fellowships towards the end of the post.

This role is part of a BBSRC-funded project to investigate RNA structural ensembles in silico. You will work on studying RNA structural ensembles and develop new tools to sample these ensembles more efficiently. These will continue current research in the group that integrates ML into physics-based simulations and on a coarse-graining model developed in collaboration with external partners.

The aim of this project is to enable fast and accurate simulations of RNA structural ensembles, which in turn will be used to identify potential binding sites for small ligands. The work will be conducted in close collaboration with experiment (Prof. Conte’s lab at KCL) and with external collaborators at the University of Cambridge and Universite de Paris.

You will be able to develop skills in scientific programming, RNA structural biology, integrative modelling and ligand discovery. There will be opportunities to present the work at international conferences. You will be expected to present work internally, actively follow open science principles and produce software that is well documented. There may be opportunities to train Masters and PhD students in the research group.

This role requires a significant amount of experience in scientific computing and molecular simulations (see essential criteria). This role is therefore only suitable for candidates with such background. If you are not sure that you meet this criterion, please contact Dr. Roeder for more detail.

You will join a team of climate scientists and artificial intelligence experts to generate new projections of the land ice contribution to sea level rise until 2300 with machine learning.

You will develop probabilistic machine learning “emulators” of multiple ice sheet and glacier models, based on large ensembles of simulations extending to 2300. 

The simulations will be from two international projects aiming to inform the Intergovernmental Panel on Climate Change Seventh Assessment Report (AR7): PROTECT (EU Horizon 2020), which has produced thousands of ice sheet and glacier simulations, and ISMIP7 (Ice Sheet Model Intercomparison Project for CMIP7), which will have new ice sheet simulations in 2026. You will use your emulators to make projections of the ice sheet and glacier contributions to global mean sea level to 2300, calibrate these projections with observational data, and compare the results with those from other emulators of similar datasets (e.g. Gaussian Process methods by the project lead). These results will inform the IPCC AR7, and adaptation and mitigation policymaking by other global stakeholders.

You will bring information science and data management expertise into the new Leverhulme Centre for Research on Slavery in War.  The new Centre for Research on Slavery in War is structured around four interconnected research strands—(Re)conceptualising, Understanding, Forecasting and Tackling—and aims for far-reaching insights that transform global responses to modern slavery in conflict settings.

The role is based within the Understanding strand, in the Department of Digital Humanities in the Faculty of Arts and Humanities. The Understanding strand will map the distribution, prevalence and forms of slavery across diverse conflict zones in the modern world, building a new analytical paradigm to understand the phenomenon of slavery in war. Key research questions include: how has slavery manifested in war? How can diverse datasets be synthesised and analysed to research and address slavery in war? By working across the Centre’s datasets and using data analytics and machine learning, this Centre strand will build a blended data resource that can help to gauge the prevalence, forms, and distribution of slavery in wars.

Food allergies are increasing, affect 8% of children and 10% of adults and can be life-threatening. With no cure, patients must avoid allergens and carry emergency medication, leading to restricted social lives and anxiety. While immunotherapy can raise the reaction threshold, it does not eliminate life-style limitations and risk of reactions. Urgent action is needed to develop definitive treatments for food allergies.

Exposure to food allergens through the gastrointestinal tract is tolerogenic. Peanut consumption from the first year of life reduced peanut allergy by 81% in a randomised-controlled trial. This impressive effect was allergen-specific and sustained over time. However, the underlying immune mechanisms of oral tolerance induction to peanut are not well understood.

In this research programme, we will use unique samples from young children undergoing their first oral exposure to peanut to explore the changes in the immune response to peanut induced by oral exposure. This work will be done in close collaboration with the Neves Lab at King’s College London, where a novel co-culture of human gut organoid models will be established with patients’ immune cells. This collaborative effort will allow us to pinpoint key pathways involved in establishing oral tolerance to food allergens and explore how they can be modulated to develop curative treatments for food allergies.

We are looking to appoint a full-time (1.0 FTE) Research Associate as part of a Faraday Institution funded project on battery fire modelling, specifically focusing on thermal runaway and cell-to-cell propagation of flaming combustion. The role-holder will be part of a larger team on the SAFEBATT Project, major grant of the faraday institution, being led by UCL.  At King’s, you will be joining a department with new laboratory facilities.

We are seeking a highly motivated Junior Clinical Research Fellow to join our team for a one-year fixed-term appointment, working at the interface of clinical trials and translational cancer immunology research. This unique role offers a 50:50 split between clinical and laboratory responsibilities, providing an excellent opportunity for a medically qualified individual to gain experience in both patient-facing research and wet lab science.

The postholder will be responsible for recruiting patients into clinical trials and research studies, conducting outpatient visits, and supporting trial-related documentation and compliance. They will work closely with clinical teams to identify eligible participants and ensure high-quality engagement with trial protocols.

In parallel, the fellow will contribute to translational research activities in the laboratory, processing patient-derived samples and performing immunological and molecular assays. The role involves working within a multidisciplinary research team focused on understanding cancer immunology and developing novel therapeutic approaches.

We are looking for an enthusiastic Postdoctoral Research Associate to lead a project on ultrasound-mediated brain tumour treatment using drug-loaded liposomes.

The successful candidate will have a good understanding of therapeutic ultrasound, Liposome drug delivery systems, in vivo imaging techniques, such magnetic resonance imaging (MRI) and near-infrared fluorescence (NIRF)/luminescence imaging. The candidate should have suitable skills in chemistry and liposome synthesis. The liposomes will be characterised for their size and drug content (HPLC and MS). These will be tested for their ability to deliver drugs into the brain of tumour mouse models and assess the antitumour effect of this therapeutic method. The candidate should have the skills to develop patient derived organoids for orthotopic injection in mice. The candidate should also be responsible for the assembly and maintenance of ultrasound equipment used in the project. Focused Ultrasound and circulating microbubbles will be used to non-invasively disrupt the blood-brain barrier in a localised and reversible manner, followed by targeted drug release through mild hyperthermia. The candidate will use ultrasound and perform in vivo experiments aiming at non-invasive treatment of Glioblastoma.

The project’s primary goal is to investigate how low-dose IL-2 affects the neuro-inflammatory process. You’ll use advanced cellular immunology techniques to conduct deep phenotypic and functional characterisation of regulatory T cells (Tregs), establishing their relationship with treatment responses and disease activity.

This is an excellent opportunity to contribute to a collaborative research program dedicated to improving our understanding of ALS and informing future clinical trials. You’ll also benefit from being part of a larger team investigating Treg biology and Treg-focused immunotherapies in other diseases.

The ideal candidate will have a strong background in cellular immunology and be proficient in analysing complex single-cell data. We utilise cutting-edge techniques, including high-dimensional flow cytometry (using CyTek Aurora) and single-cell transcriptional profiling (using 10x Genomics)

Excellent communication skills and a passion for learning new assays and analysis techniques are essential.

The position is based at Guy’s Hospital, giving you access to state-of-the-art core facilities for flow cytometry, genomics, and bioinformatics. This role provides a unique opportunity for an ambitious scientist to advance their career in translational immunology.

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral Research Associate in Histology and Spatial Biology – INTERNAL ONLY

Deadline :03 September 2025.

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Applications are invited for an enthusiastic Postdoctoral Research Associate to work with the Brain Health in Gen2020 preclinical team, led Dr. Katie Long in the Centre of Developmental Neurobiology and King’s College London. Brain Health in Gen2020 is a joint preclinical and clinical research programme that aims to map the fetal origins of childhood brain health and the impact of COVID-19 on these processes.

This project is part of the Brain Health in Gen2020 programme, and will aim to characterise the cell behaviour of early human cortical progenitors and the effect of COVID-19 infection on these behaviours.

Candidates should have, or be about to obtain (thesis submitted), a PhD in Developmental Neuroscience . They should have strong experience in human developmental neuroscience, imaging techniques and bioinformatic analysis of microscopy images, RNAseq data and/or spatial transcriptomics. Experience with confocal imaging, human fetal cortex tissue, RNAseq and image analysis are all essential.