Karolinska Institute, Sweden invites online Application for number of Fully Funded PhD Degree at various Departments. We are providing a list of Fully Funded PhD Programs available at Karolinska Institute, Sweden.
Eligible candidate may Apply as soon as possible.
(01) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Cognitive Neuroscience
The candidate will work on a research project investigating the multisensory mechanisms underlying the experience of perceiving an entire body as one’s own (‘sense of body ownership’), focusing on how various body parts, especially the head, contribute to this fundamental experience. The project employs full-body illusions and advanced functional magnetic resonance imaging (fMRI) analyses to explore the brain mechanisms that support the sense of owning an entire body and the specific role of the head in this process.
The candidate is expected to develop into an independent scientist over the four years of the program. They will be encouraged to formulate their own experimental ideas to further develop this novel research project. This doctoral project will provide opportunities for the candidate to contribute to innovative findings within the field.
Deadline : 17.Jan.2025
(02) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in clinical epidemiology with focus on maternal vaccination
In this doctoral project, we will study vaccination during pregnancy, focusing on the safety of vaccinations for the pregnant individual, the fetus, and the child; the effectiveness of vaccines against severe infections during pregnancy and infancy; and factors related to women’s willingness and reluctance to vaccinate during pregnancy. The project includes register-based epidemiological studies as well as qualitative interview studies. The long-term goal of the project is to contribute knowledge that can lead to increased trust in vaccines in society, targeted interventions to enhance vaccination uptake during pregnancy, and, ultimately, a reduced burden of disease in the population.
The doctoral student will be involved in all parts of the project, ranging from contributing to the study protocol and study design, data management from large population-based registers, in-depth qualitative interviews, statistical and qualitative data analysis, writing scientific publications, and disseminating the results. The position will involve theoretical studies and training in epidemiology and qualitative design, advanced statistical methods, and public health. The doctoral student is also encouraged to attend relevant seminars at the department and present the study results at national and international conferences.
Deadline : 20.Dec.2024
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(03) PhD Degree – Fully Funded
PhD position summary/title: Doctoral position in translational molecular psychiatry
To complete a doctoral education means to devote oneself to a research project under supervision of an experienced researcher and to follow an individual study plan. The doctoral student will also take courses and write a thesis. After completing their doctoral education at KI, students are to have developed an advanced general knowledge of medical science and scientific methodology, and cutting edge scientific skills. For this project the student will, using transcriptomic methods and virus-induced genetic engineering, study changes in the brain during schizophrenia using both mouse models and human tissue.
Deadline : 13.Dec.2024
(04) PhD Degree – Fully Funded
PhD position summary/title: PhD student position in Inflammation and Metabolism
The doctoral project, titled “Modulation of Metabolic Balance and Tissue Remodelling in Skeletal Muscle by Unsaturated Fatty Acid” aims to investigate the role of inflammatory mediators with a special focus, but not limited to the study of cytokines and oxylipins—bioactive metabolites derived from unsaturated fatty acids—in skeletal muscle metabolism, inflammatory responses, and tissue remodelling. The doctoral student will explore inflammatory signalling pathways, their impact on glucose metabolism, and their role in muscle remodelling using advanced molecular biology, bioinformatics, and in vivo techniques. Key responsibilities include conducting bioinformatic analyses on OMIC datasets, performing metabolic assays with human skeletal muscle cultures, and participating in in vivo studies to assess the effects of inflammatory mediators on whole-body metabolism. This hands-on project provides a comprehensive training in metabolic research, cell biology, and bioinformatics, supporting the student’s development into an independent researcher capable of leading translational projects in muscle biology and metabolic health.
Deadline : 13.Dec.2024
(05) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Psychiatric Genetics with focus on depression and eating disorders
Major depressive disorder (MDD) and eating disorders (ED) are debilitating mental health conditions that often co-occur, significantly complicating diagnosis, treatment, and outcomes for affected individuals. It underscores the urgent need for a comprehensive understanding of the underlying mechanisms that drive this relationship. By elucidating these mechanisms, we can develop more effective interventions targeting shared pathways and addressing the complex interplay between these disorders.
The mechanisms underlying the MDD-ED comorbidity are likely multifaceted, involving a combination of biological, psychological, and social factors. Therefore, the overall aim of this PhD program is to advance our understanding of these mechanisms by systematically testing hypotheses related to shared psychosocial and biological factors, potential casual links between the two disorders, and the implication of causal links for guiding treatment.
Deadline : 11.Dec.2024
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(06) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in High throughput selection of DNA structures for targeted cell delivery
In the last decades it’s been shown that nucleic acid therapeutics, can knock in/out, silence/promote or edit genes, offering unique routes to cures for a diverse set of diseases, but they need to be delivered to the right cells to have correct effect. DNA nanostructures are a natural choice as they can directly hybridize with the therapeutic molecules and change their geometry, link them to targeting moieties, and protect them by coatings.
We have developed a system for evolutionarily selecting DNA structures that are preferentially taken up by certain cells. In this research project the student will work to design DNA nanostructure libraries and perform selection against cell models. The selection process will be monitored by high throughput sequencing paired with custom bioinformatics and high throughput structure prediction tools. Promising candidate structures will then be produced individually and screened by microscopy and in vitro gene silencing assays to validate effective cell delivery.
Deadline : 11.Dec.2024
(07) PhD Degree – Fully Funded
PhD position summary/title: Doktorandplats inom teknikförstärkt träning för personer med Parkinsons sjukdom
Detta doktorandprojekt är ett delprojekt i det större ParkMOVE-projektet. ParkMOVE projektet syftar till att utveckla och utvärdera ett nytt teknikförstärkt motor-kognitivt träningskoncept för behandling av personer med Parkinsons sjukdom. Doktorandprojekt kommer att innefatta både kvalitativa och kvantitativa metoder, för datainsamling och analys, vilket erbjuder doktoranden ett brett utbud av vetenskapliga verktyg att lära sig och fördjupa sina kunskaper inom.
Projektet är uppdelat i tre faser. I fas 1 kommer vi att utarbeta grunden för hur träningskonceptet ska utformas. Denna innefattar bland annat individuella intervjuer med personer med Parkinsons sjukdom. I fas 2 kommer vi att utveckla träningskonceptet genom en samskapande process (workshops/fokusgruppsintervjuer) vilket innebär återkommande loopar av designande, utvecklande, och utvärderande av delkomponenter i träningskonceptet. Det framtagna träningskonceptet tas sedan vidare in i fas 3, där vi kommer att testa genomförbarheten av träningskonceptet och studiedesignen inför en efterföljande randomiserad kontrollerad studie.
Deadline : 2024-12-10
(08) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Stem Cells and Metabolism
The doctoral student will study how metabolism of a cell is influenced by the types of mitochondria the cell has, and use mitochondrial transfer as an approach to alter metabolism and fate decisions in the recipient cells. She/he will run independent experimentation taking the benefit of our novel mouse models and organellar targeting approaches.
A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.
Deadline : 06.Dec.2024
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(09) PhD Degree – Fully Funded
PhD position summary/title: Doctoral Position to the Unit of Metals and Health
The doctoral project builds on several ongoing projects and is centered upon identifying the impact of early-life exposure to metal mixtures on child growth and underlying molecular mechanisms. This will be done by combining epidemiological studies and experimental studies using zebrafish models. The expected starting date is in early January 2025.
The doctoral student will be expected contribute to designing, performing, analysing, and interpreting epidemiology-based and experimental-based studies and different data layers arising from these, as well as to present results in scientific text. The student will be expected to present his or her results at national and international conferences and meetings and to discuss the research and results with the scientific community and with different groups in society. The student is also expected to participate in joint activities at IMM and the unit of Metals and Health, to contribute to teaching and to participate in doctoral courses and other learning activities at Karolinska Institutet.
Deadline : 06.Dec.2024
(10) PhD Degree – Fully Funded
PhD position summary/title: PhD Position in Glioblastoma Immunology
We seek a highly motivated PhD student to lead a project in brain onco-immunology, specifically investigating the phenotype, location, and function of immune cells within the tumor microenvironment of glioblastoma. This role will immerse you in an intellectually stimulating research environment, where you will collaborate closely with an experienced postdoc in human immunology, as well as other PhD students, postdocs, staff scientists, clinicians, and research nurses.
Deadline : 05.Dec.2024
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(11) PhD Degree – Fully Funded
PhD position summary/title: Doktorandplats inom kardiologi
De översiktliga målen med doktorandprojektet är att 1) studera sekundärpreventiv måluppfyllelse vid kardiovaskulär sjukdom och dysglykemi på en internationell nivå 2) öka förståelsen av nya diabetesläkemedels hjärt-kärlskyddande effekter genom att studera biomarkören pro-neurotensin samt att genomföra en mindre randomiserad klinisk prövning. Projektet kommer att genomföras tillsammans med nationella och internationella samarbetspartners.
Doktoranden kommer huvudsakligen arbeta inom ramen för de av våra delprojekt som handlar om typ 2 diabetes sekundär prevention och biomarkörer. I Delarbete I och V kommer doktoranden studera sekundär prevention vid diabetes och prediabetes. Detta kommer att studeras dels en internationell observationsstudie där patientmaterialet är insamlat dels in en europeisk studie som för närvarande pågår. Doktoranden kommer att vara delaktig i planering av studieprotokoll, statistisk bearbetning och tolkning av resultaten. I Delarbete II och IV ska doktoranden studera biomarkören pro-neurotensin, dels i insamlat patientmaterial i den kliniska prövningen SOCOGAMI, dels i material som kommer att samlas in i delstudie III. Delstudie III är en klinisk prövning där vi planerar att studera ett diabetesläkemedelseffekter på endotelfuntkion. I denna kommer doktoranden att vara delaktig i sammanställande av protokoll, studieplanering och genomförande inklusive patientomhändertagande samt analys av insamlat material.
Doktoranden kommer, under handledning, att utarbeta protokoll inklusive statistik planer, genomföra statistiska analyser, tolka resultaten och sammanställa dessa i vetenskapliga rapporter samt presentera resultaten vid lokala, nationella och internationella möten. I Delstudie V kommer doktoranden genomföra laboratoriska analyser av pro-neurotensin i den planerade kliniska prövningen. Doktoranden kommer att delta i utformning av etik och anslagsansökningar.
Deadline : 2024-12-04
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(12) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Neuroscience and AI
The main goal for the PhD student is to explore the potential and capacity of self-supervised learning methods for training multimodal basic models in brain imaging. In practice, this work focuses on identifying and evaluating opportunities for how large datasets of clinical data can be used to more effectively create self-supervised multimodal machine learning models that can improve the quality and latency of diagnostic methods used in clinical neuroscience and brain imaging. This topic is explored by introducing and evaluating several new approaches to building multimodal foundational models that may support and/or replace human involvement in data curation and management.
Deadline : 04.Dec.2024
(13) PhD Degree – Fully Funded
PhD position summary/title: Doktorandplats inom kariologi
Vi känner väl till att karies utgör globalt sett ett stort hälsoproblem och är orsaken till stora samhällskostnader. Sjukdomen är mångfacetterad vilket medför att omhändertagandet och behandlingarna ofta innebär en utmaning för både patienterna likväl som för tandvårdsteamet. Detta multidisciplinära doktorandprojekt syftar till att undersöka sambandet mellan genomförda behandlingar av djupa kariesangrepp och förekomsten av sjukdomar i pulpan och den periradikulära vävnaden. De aktuella behandlingsmetoderna varierar mellan fullständig avlägsning av infektionsvävnad, stegvis eliminering av infektionsvävnad, och selektiv eliminering av infektionsvävnad. Den övergripande målsättningen för projektet är att utforska och analysera riskfaktorer för utvecklingen av sjukdomar i pulpa och käkben vid olika behandlingsstrategier för djupa kariesläsioner.
Studierna inkluderar registerbaserade epidemiologiska metoder och användning av artificiell intelligens vid röntgenundersökningar för att kunna identifiera prediktionsfaktorer för lyckande behandlingsutfall vid djupa kariesangrepp. Forskningen kommer att utföras på Institutionen för odontologi, Karolinska Institutet. Doktoranden kommer att analysera lokala och nationella hälsoregisterdata, framställa digitala beräkningsmodeller samt engagera sig i vetenskapligt skrivande. Dessutom kommer studenten aktivt delta i institutionsseminarier, presentera forskningsresultat vid internationella/nationella konferenser, delta i doktorandkurser och bidra till avdelningens drift och dynamik.
Deadline : 2024-12-04
(14) PhD Degree – Fully Funded
PhD position summary/title: Doktorandplats inom virologi och immunologi
I detta projekt kommer doktoranden att undersöka detaljer kring värdcellsinträdet för flera virus med förhöjd pandemipotential. Kandidaten kommer att använda högkapacitetsanalyser och ett systematiskt tillvägagångssätt för att avslöja mekanistiska insikter som är avgörande för att vägleda utvecklingen av effektiva vacciner och antivirala behandlingar. Doktoranden förväntas vara drivande i analysen och tolkningen av resultaten samt anta ett kreativt förhållningssätt till immunologi och proteinbiokemi för att designa nya antiviraler och vaccinkandidater. Genom detta arbete kommer doktoranden att bidra till att öka kunskapen inom virologi och immunologi och därmed hjälpa till att förbereda för framtida pandemier.
Deadline : 2024-12-02
(15) PhD Degree – Fully Funded
PhD position summary/title: Doktorandplats neurovetenskap med inriktning mot experimentell neurotraumatologi
En kreativ, internationell och inspirerande miljö fylld av kompetens och nyfikenhet. Karolinska Institutet är ett av världens ledande medicinska universitet. Här bedriver vi framgångsrik medicinsk forskning och har det största utbudet av medicinska utbildningar i Sverige. På KI får du träffa forskare med olika forskningsinriktningar som jobbar tillsammans. Det är det gränsöverskridande samarbetet som bidrar till KI:s världsledande position inom forskning. Som doktorand erbjuds du ett individuellt forskningsprojekt, en välutbildad handledare, ett stort utbud av valbara kurser och möjligheten att arbeta i en framgångsrik forskargrupp. Karolinska Institutet har samarbeten med framstående universitet över hela världen, vilket ger möjlighet till internationella utbyten. Som anställd doktorand får du en avtalsenlig lön, du får träna fritt i våra moderna friskvårdsanläggningar och du får ersättning för läkarvård.
Deadline : 2024-12-02
(16) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in 7 Tesla neuroimaging research
The doctoral project will investigate the advantages of 7 Tesla magnetic resonance imaging (MRI) compared to 3 Tesla MRI in diagnosing and planning treatments for epilepsy, focusing on volumetric imaging, presurgical planning, and the functional and structural aspects of pharmacoresistant epilepsy. Through volumetric analysis, functional MRI (fMRI), diffusion-weighted imaging, and advanced techniques like laminar fMRI and elastography, the studies aim to improve detection of epilepsy-related brain pathologies, particularly within the hippocampus and seizure-onset zones. By enhancing the precision of imaging in epilepsy diagnostics, this project seeks to support more effective presurgical mapping, better localization of epileptic foci, and better treatment strategies.
The doctoral student will participate in patient recruitment, data collection, and advanced image analysis, utilizing specialized software for tasks such as segmentation, fMRI, and DTI processing. The student will also interpret findings, contribute to multidisciplinary discussions on surgical planning, and communicate results through scientific presentations and publications under the guidance of supervisors, ultimately aiming to advance understanding and clinical outcomes for epilepsy patients.
Deadline : 30.Nov.2024
(17) PhD Degree – Fully Funded
PhD position summary/title: Doktorandplats inom neuroimmunologi
The project focusses on understanding how adaptive immune responses to viruses associated with multiple sclerosis (MS) – such as Epstein-Barr virus (EBV) – are involved in disease development and/or progression. The student will carry out experimental investigations encompassing T cell and B cell responses to virus antigens and self-proteins, using a variety of immunological techniques from cell culture to immune receptor sequencing. Work with data analysis and statistical methods of collected data will be a large part of the doctoral studies, and the student will also collaborate with other members of our unit performing rodent experimental MS models.
Deadline : 30.Nov.2024
(18) PhD Degree – Fully Funded
PhD position summary/title: Doktorandplats inom infektionsimmunologi
Infektionssjukdomar är en betydande källa till global dödlighet och sjuklighet. Även om vacciner är mycket effektiva för att kontrollera spridningen av vissa sjukdomar, har det visat sig vara mycket svårt att utveckla effektiva vacciner mot vissa patogener, såsom HIV-1, Mycobacterium tuberculosis och Plasmodium falciparum (malaria). För tuberkulos utvecklar de flesta infekterade personer inte aktiv sjukdom, vilket tyder på att deras immunsvar är tillräckligt för att kontrollera infektionen. Detta doktorandprojekt syftar till att undersöka de mekanismer som är ansvariga för detta skydd.
Arbetet som ska utföras av doktoranden inkluderar kontakt med patienter, förberedelse och organisering av prover för vår biobank, ex vivo- och in vitro-cellodling, cellbiologiska och molekylära tekniker för att undersöka cellfunktion samt sekvensering och bioinformatisk analys på patientprover eller efter stimulering.
Deadline : 2024-11-29
(19) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Photon-Counting Computed Tomography research
The doctoral project will investigate the potential of Photon-Counting Computed Tomography (PCCT) in neuroimaging, particularly as an alternative to Magnetic Resonance Imaging (MRI) for volumetric analysis of the brain in populations where MRI accessibility may be limited. The project will assess the accuracy, variability, and clinical relevance of CT-based volumetry techniques compared to MRI standards, focusing on key brain structures, including grey matter, white matter, and intracranial volumes. Through a combination of atlas-based and deep-learning methods, such as CTseg and SynthSeg, the study aims to validate PCCT’s effectiveness in neuroanatomical segmentation, potentially offering a cost-effective solution for widespread clinical use. The project aims to develop a machine learning-based volumetric analysis technique tailored for PCCT, specifically designed for integration into clinical workflows to enhance accessibility and precision in neuroanatomical diagnostics.
The doctoral student will be responsible for data acquisition, segmentation analysis, and validation of the volumetric findings against MRI-based data, leveraging specialized software like FreeSurfer, SPM12, and advanced machine learning models for imaging analysis. They will manage a dicom library and data server, support network and enterprise connectors, interpret volumetric results, explore correlations with cognitive scores, and support a streamlined design for the clinical applicability of PCCT-based techniques. Furthermore, the student will contribute to interdisciplinary clinical discussions, present findings in scientific forums, and work toward the implementation of PCCT in clinical workflows under their supervisors’ guidance. This project aims to enhance diagnostic accessibility and accuracy, particularly for patients requiring neuroimaging investigation.
Deadline : 29.Nov.2024
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(20) PhD Degree – Fully Funded
PhD position summary/title: Doctoral student in physics-driven image analysis and modelling for personalized vascular diagnostics
The overall goal of the project is to investigate hemodynamic and biomechanical features of aortic dissection growth, improving on current diagnostic paradigms for clinical risk prediction using multimodal image analysis. Aortic dissection is a life-threatening vascular disease where the aortic wall partially tears allowing blood to form a new cavity within the wall. Whilst most patients survive into a chronic phase, long-term survival remain low and an urgent need for personalized diagnostic measures exist. To approach this, our group have shown how novel medical imaging allow for interrogation of functional dissection behaviour going beyond current practice in assessing individual risk. In particular, through incorporation of fundamental fluid mechanical concepts and cardiovascular modelling principles, we have been exploring the concept of physics-based image analysis to extract functional information underpinning dissection risk, opening for novel diagnostic paradigms.
As a Ph.D. student you will continue these advancements by exploring and implementing methods to extract hemodynamic and biomechanical information of aortic dissection from clinical image data. This will include formulating the theoretical concepts of the methodologies, building cardiovascular models to validate approaches, and evaluating setups in clinically acquired image sets and patient cohorts. Based in a highly translational research environment, the Ph.D. project will entail aspects ranging from fluid mechanical theory, cardiovascular modelling, computational image analysis, to clinical vascular care; all seeking to translate physics-informed imaging tools into aortic dissection care.
The project is formulated as a direct collaboration between Karolinska Institutet (Dr. Marlevi; Prof. Hultgren) and the University of Michigan (Prof. Nordsletten), providing a unique environment for translating advanced bioengineering into clinical practice. Close interaction across both institutes are expected within the announced Ph.D. project.
Deadline : 27.Nov.2024
About The Karolinska Institute, Sweden – Official Website
The Karolinska Institute sometimes known as the (Royal) Caroline Institute in English is a research-led medical university in Solna within the Stockholm urban area of Sweden. The Nobel Assembly at the Karolinska Institute awards the Nobel Prize in Physiology or Medicine. The assembly consists of fifty professors from various medical disciplines at the university. The current rector of Karolinska Institute is Ole Petter Ottersen, who took office in August 2017.
The Karolinska Institute was founded in 1810 on the island of Kungsholmen on the west side of Stockholm; the main campus was relocated decades later to Solna, just outside Stockholm. A second campus was established more recently in Flemingsberg, Huddinge, south of Stockholm.
The Karolinska Institute is Sweden’s third oldest medical school, after Uppsala University (founded in 1477) and Lund University (founded in 1666). It is one of Sweden’s largest centres for training and research, accounting for 30% of the medical training and more than 40% of all academic medical and life science research conducted in Sweden.
The Karolinska University Hospital, located in Solna and Huddinge, is associated with the university as a research and teaching hospital. Together they form an academic health science centre. While most of the medical programs are taught in Swedish, the bulk of the PhD projects are conducted in English. The institute’s name is a reference to the Caroleans.
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