23 Postdoctoral Fellowship at Saint Louis University, Missouri, USA

An NIH-supported postdoctoral position is immediately available for an exceptionally motivated and creative individual in the laboratory of Dr. Anutosh Chakraborty at Saint Louis University, Missouri. The Chakraborty lab aims to understand molecular mechanisms that regulate the development and progression of obesity, insulin resistance, and NAFLD/NASH. The goal of the lab is to develop new therapeutic approaches for the treatment of these diseases. Prior work from the lab established that the enzyme inositol hexakisphosphate kinase-1 is a pharmacologic target in metabolic diseases. 

Saint Louis University’s College of Arts and Science invites applications for a three-year Post-Doctoral Fellow. The successful applicant will work with a faculty-led team in the University-CORE at SLU for a new initiative, Confluence: Where the Sciences Meets the Humanities. This initiative is supported by a Cornerstone: Learning for Living grant, funded by the Teagle Foundation, under the auspices of the National Endowment for the Humanities. Our goal is to create a program of general education based in “transformative texts.” Such texts—similar to “great books”—are, in the words of the “Teagle Foundation,” primary source “works of literature, art, and philosophy” that raise questions that students are “otherwise unlikely to encounter in their undergraduate career, and at a moment in their lives when they are open to confronting humanistic questions as part of their education.” Such texts can come from across the disciplines and frequently highlight the interconnected nature of academic knowledge. This program, while available to all SLU undergraduates, will be specifically targeted at students in STEM fields.

The Ferris lab at Saint Louis University in St. Louis, MO, is seeking a full-time postdoctoral research associate in the fields of tumor immunology and autoimmunity. We study the dendritic cells required to mount adaptive T cell responses in the context of tumors and autoimmunity to better understand tumor evolution and identify novel therapeutic strategies that can improve patient outcomes. The successful candidate will be highly motivated and intellectually invested. They will have the opportunity pursue their own ideas that are relevant to the overall goals of the lab and drive their own research projects. Dr. Ferris is an Assistant Professor in the Department of Molecular Microbiology and Immunology. MMI houses a diverse variety of research groups studying virology and innate and adaptive immune responses in the context of viral infection, cancer, and autoimmunity. MMI is a highly collaborative community, meaning the successful candidate will have the opportunity to form relationships with many different laboratory groups and faculty members.

An immediate postdoctoral position is available in the lab of Gucan (Gabriel) Dai at the Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine. We are seeking candidates with a solid publication record in biophysics and biochemistry, specifically in the field of ion channels or membrane proteins. Prior experience in patch-clamp electrophysiology or fluorescence cell imaging using advanced fluorescence microscopy techniques is highly preferred. The Dai lab focuses on investigating the fundamental mechanisms underlying ion channels of excitable membranes, employing a multidisciplinary approach that combines structural biology, chemical biology, genetics, fluorescence microscopy, and electrophysiology. Notably, our lab is equipped with a state-of-the-art frequency-domain fluorescence lifetime imaging microscopy, which is the only one of its kind in the state of Missouri.

The Taylor Geospatial Institute (TGI), the nation’s leading academic center for geospatial science, is committed to making St Louis a global center of excellence in geospatial science research, education, and innovation. The St. Louis region is well-positioned to become the nation’s geospatial ‘Silicon Valley’ as laid out in the June 2020 “GeoFutures Strategic Roadmap,” a plan for strengthening St. Louis’s competitive advantage in geospatial research and technology. For more information on the Institute please visit www.taylorgeospatial.org. To achieve this goal, the Taylor Geospatial Institute is announcing a Postdoc program that is designed to support local faculty in their research projects in core geospatial science and applied domains (www.taylorgeospatial.org/research/). The Taylor Geospatial Institute envisions building a world-class, interdisciplinary geospatial science research collaborative to address scientific and societal grand challenges (e.g. food security, supply chain resilience, health equity, and national security). The purpose of the Taylor Geospatial Institute postdoctoral program is to bring distinguished researchers in geospatial science core or adjacent fields to the St. Louis region, develop the next generation of scientific leaders, and catalyze regional collaboration to accelerate the St. Louis region’s development as a global geospatial center of excellence. This program is another step to demonstrate our commitment to advancing the geospatial sciences.

NIH funded postdoctoral positions are available to study the structural enzymology of proteins responsible for blood coagulation (https://biochem.slu.edu/faculty/dicerawp/) with the goal of unraveling the molecular architecture and mechanism of the underlying interactions. The approach uses a combination of conventional (rapid kinetics, protein engineering, X-ray crystallography) and innovative (smFRET, cryo-EM) biophysical techniques. Current projects in the lab focus on the interaction of prothrombin with prothrombinase, leading to generation of thrombin and blood clotting, the activation of factor V required for assembly of prothrombinase and the interaction of the thrombin-thrombomodulin complex with protein C that halts the coagulation response. Additional studies focus on factor V short and its interactions with TFPIalpha, protein S and factor Xa and on proteins of the contact pathway like factors IX, XI and XII. Experience in rapid kinetics, smFRET, X-ray crystallography, NMR, or cryoEM is required.

The Alspach lab at Saint Louis University in St. Louis, MO, is seeking a full-time postdoctoral research associate in the fields of tumor immunology and sex disparities. We study the impacts of biologic sex on anti-tumor T cell responses to better understand tumor evolution and identify novel therapeutic strategies that can improve patient outcomes. The successful candidate will be highly motivated and intellectually invested. They will have the opportunity pursue their own ideas that are relevant to the overall goals of the lab and drive their own research projects. Dr. Alspach is an Assistant Professor in the Department of Molecular Microbiology and Immunology. MMI houses a diverse variety of research groups studying virology and innate and adaptive immune responses in the context of viral infection, cancer, and autoimmunity. MMI is a highly collaborative community, meaning the successful candidate will have the opportunity to form relationships with many different laboratory groups and faculty members.

The laboratory of Dr. Angel Baldan in the Department of Biochemistry and Molecular Biology at Saint Louis University has an immediate opening for a junior postdoctoral fellow with proven expertise in lipid/sterol metabolism, ncRNAs, RNA-seq, and/or molecular mechanisms of diet-induced diseases (CVD, NAFLD, obesity). The Baldan laboratory has ongoing research programs related to lipid droplet-associated proteins, sterol-regulated ncRNAs, and liver/adipose/intestinal/lipoprotein lipid homeostasis. An independent and highly motivated candidate with a recent Ph.D. degree and rigorous training in molecular/cell biology is required for the position. Competitive candidates have two or more first-author publications and are experienced and comfortable working with mice. Candidates with research experience in bioinformatics and next-generation sequencing are preferred but not required.

A postdoctoral position is available immediately in the laboratory of Dr. Amina Mohammadalipour at Saint Louis University, St. Louis, MO. Alipour lab combines biophysics, mechanobiology, structural biology, membrane proteins, and genetics to understand the fundamental mechanisms underlying cancer cells’ rheological properties. Past experiences with cell culture, flow cytometry, fluorescence microscopy, and live imaging are required. Experiences in micropipette aspiration, AFM, flow chambers/microfluidic devices, Western blotting, and PCR are preferred but not required.

The Postdoctoral Fellow will assist the Principal Investigator. The incumbent will conduct research and ensure that all experiments are appropriately conducted following the policies and procedures of Saint Louis University.

Tuberculosis (TB) remains a leading health problem worldwide. The lack of highly effective preventive vaccine, the emergence of drug-resistant strains, and an epidemic in HIV patients make TB a worsening threat. Host-directed therapy (HDT) is a promising approach for treating drug-resistant TB. This NIH-funded position is to investigate the host protective immune mechanisms and develop new HDT against Mycobacterium tuberculosis infection.  Postdoctoral position is available immediately for researchers (Ph.D., D.V.M. or M.D.) with strong background in molecular biology and immunology. Previous experience in TB research is desired.  

NIH-funded postdoctoral positions are available for highly motivated postdoctoral fellows to join the laboratory of Dr. Aubin Moutal, in the Department of Pharmacology and Physiology at St Louis university to study novel proteins involved in chronic pain in the context of autoimmunity. Our work focuses on first identifying determinants of the transition from acute to chronic pain by reverse translating clinical findings to then perform a complete mechanistic characterization of how these new factors influence chronic vs physiological pain. The PI has a strong record of high impact papers with multiple recent publications in Science Translational Medicine, Pain, and PNAS. Through the active external collaborations with the New York University (Dr. Rajesh Khanna), the University of Arizona (Dr. Frank Porreca) and with the Institut neuromyogene in France the candidate will also grow an interest in ion channel regulation, central mechanisms of pain and paraneoplastic syndromes, respectively. Major techniques include immunohistochemistry, protein-protein interactions and protein biochemistry are employed to support findings from our behavioral and electrophysiological experiments. Applicants should have a strong background in molecular biology, IF, IHC, Western analysis, and enzyme assays; experience with phosphorylation, ubiquitination, and/or a mouse colony are pluses. Successful applicants will be highly motivated individuals with good communication skills, will have a proven publication record, and the ability to work independently. The applicants must currently have a Ph.D. in Biochemistry, Neuroscience or a related field. The appointment will be for 2 years with renewal up to 5 years and a competitive salary following NIH guidelines. Email a single PDF containing a CV, 1-2 pages summary of past research accomplishments, and contact information for three references to: [email protected]. All questions are welcome!

The Saint Louis University School of Education and SLU PRiME Center is seeking applications for the position of Postdoctoral Research Associate. Successful candidates will conduct applied education policy research for the SLU PRiME Center in the School of Education, serving as data analysts and researchers, while also continuing to work on their own research agendas. Candidates will have the opportunity to lead project teams, provide input on the Center’s research agenda, and assist with the mentorship of graduate and undergraduate research associates. The Postdoctoral Research Associate (Postdoctoral Fellow) will work closely with a large research team (including researchers in the SLU PRiME education policy research center and SLU Education Policy faculty and graduate students) to conduct research on Missouri education. The ideal candidate will have experience conducting program evaluations and designing research projects related to education policy issues.

NIH-funded postdoctoral positions are available for highly motivated postdoctoral fellows to join the laboratory of Dr. Aubin Moutal, in the Department of Pharmacology and Physiology at St Louis university to study novel proteins involved in chronic pain in the context of autoimmunity. Our work focuses on first identifying determinants of the transition from acute to chronic pain by reverse translating clinical findings to then perform a complete mechanistic characterization of how these new factors influence chronic vs physiological pain. The PI has a strong record of high impact papers with multiple recent publications in Science Translational Medicine, Pain, and PNAS. Through the active external collaborations with the New York University (Dr. Rajesh Khanna), the University of Arizona (Dr. Frank Porreca) and with the Institut neuromyogene (Dr. Jérôme Honnorat) in France, the candidate will also grow an interest in ion channel regulation, central mechanisms of pain and paraneoplastic syndromes, respectively. Major techniques include immunohistochemistry, protein-protein interactions and protein biochemistry are employed to support findings from our behavioral and electrophysiological experiments. Applicants should have a strong background in animal surgeries and behaviors or electrophysiology or molecular biology, IF, IHC, Western analysis, and enzyme assays. Successful applicants will be highly motivated individuals with good communication skills, will have a proven publication record, and the ability to work independently. The applicants must currently have a Ph.D. in Biochemistry, Neuroscience or any related field. The appointment will be for 2 years with renewal up to 5 years and a competitive salary following NIH guidelines. Email a single PDF containing a CV, 1-2 pages summary of past research accomplishments, and contact information for three references to: [email protected]. All questions are welcome!

 

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Post Doctoral Fellow – Pediatrics

Deadline : Open Until Filled

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The Postdoctoral Fellow will be expected to pursue high quality scholarship and collaborate with faculty in economics, finance, and other disciplines across campus to conduct research in areas related to urban economics, regional economics, transportation economics, economic development, economics of education, or public policy. This will involve data preparation and cleaning, spatial econometric data analysis and related programming, co-authorship of scholarly research papers. Through the newly established Taylor Geospatial Institute, Saint Louis University is currently building an ambitious research agenda in Geospatial Science. The Sinquefield Center for Applied Economic Research (SCAER) is an integral partner in this university-wide strategic plan. Researchers associated with the Center are making extensive use of large spatial datasets for economic, business, and public policy research.

A postdoctoral position is available immediately in the lab of Gucan “Gabriel” Dai at the Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine. Candidates with a strong publication record in biophysics and biochemistry in ion channels or membrane proteins are encouraged to apply. Past experiences in patch-clamp electrophysiology or fluorescence cell imaging using advanced microscopy are preferred but not required. The Dai lab combines structural biology, chemical biology, genetics, fluorescence microscopy and electrophysiological methods to understand the fundamental mechanisms underlying ion channels of excitable membranes. The candidate is expected to publish high-impact papers as a lead author and apply for academic faculty positions or leadership positions in industry after receiving this training. The research directions in the lab are summarized in below. Applicants who are interested in this position should contact: [email protected] 

Our NIH-funded laboratory is seeking an enthusiastic postdoctoral fellow to study the immunological response and pathogenesis of viral infections. Laboratory studies are focused on the understanding of the antigen specific B cell response to infection and vaccination and how this B cell response is reflected in the polyclonal antibody response. Our laboratory uses in vitro and in vivo approaches to understand infection and disease.  Techniques include cloning and molecular biology, biochemistry, cell/tissue culture, flow cytometry, transcriptomics, and mouse models of infection. Experience in one or more of these techniques and areas is strongly preferred. You will be provided with the mentorship and resources to be successful.

Saint Louis University, a Catholic, Jesuit institution dedicated to student learning, research, health care, and service, is seeking applicants for a postdoctoral fellow in the Edward A. Doisy Department of Biochemistry and Molecular Biology, beginning in the spring of 2020.  A postdoctoral position is now available in the laboratory of Dr. Kyle McCommis. Successful candidates are expected to have a doctoral degree in a life sciences-related field, with research experience in molecular biology and/or animal physiology. The laboratory of Dr. Kyle McCommis focuses on the importance of mitochondrial metabolism in the pathogenesis and treatment of metabolic diseases such as heart failure and nonalcoholic fatty liver disease. Projects will combine in vivo animal physiology and pathology, isolated primary cell and immortalized cell cultures, as well as biochemical and molecular biology techniques. Applicants should be highly motivated, be able to think critically, and demonstrate productivity throughout previous research experiences.Compensation will be based on experience, according to the NIH pay scale. Interested candidates must submit a cover letter, application and current curriculum vitae to http://jobs.slu.edu. Saint Louis University is an Affirmative Action, Equal Opportunity Employer and encourages nominations of an application from women and minorities.