26 Postdoctoral Fellowship at Karolinska Institute, Sweden

We are looking for highly motivated candidates with a Ph.D. in epidemiology, data science, or statistics – or who can demonstrate via publications the acquisition of the necessary experience. Individuals with the following skills are encouraged to apply: excellent quantitative and applied research skills in data analysis, demonstrated proficiency in statistical language (e.g., R, Matlab), good bioinformatics knowledge of metabolomics, and strong oral and written communication skills. The candidates’s time will be devoted to data analysis, manuscript preparation, and career development. Prior experience working biological datasets, or high-dimensional data and knowledge in biology and respiratory diseases is a significant merit. Excellent communication skills and an ability to interact socially and scientifically with other members of the laboratory and with international collaborators are essential.

Increased white adipose tissue mass is linked to type 2 diabetes, which in turn can be treated with several different anti-hyperglycemic drugs. However, there are large interindividual variations in the efficacy and side-effects of these interventions. We hypothesize that distinct adipocyte subtypes determine insulin sensitivity and outcomes following interventions with anti-hyperglycemic drugs. This project will test our model by spatially resolving treatment responses in human WAT based on samples from a clinical trial called DIASPAX (NCT05501483). In the study, we obtain adipose tissue biopsies, which we will use to generate single-nucleus RNA sequencing and spatial transcriptomic data. By jointly analyzing these data together with functional assessment of the tissue and assessments of clinical phenotypes, we will for the first-time link white adipose tissue heterogeneity to treatment responses. We are now looking for an ambitious postdoctoral fellow that will perform single-nucleus RNA sequencing and spatial transcriptomic analyses. The work will be undertaken in collaboration with other experts within the group as well as with members of the lab of Patrik Ståhl at SciLifeLab. There will be possibilities to follow-up key findings with wet lab experiments using state-of-the-art methods.

The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are looking to recruit 6 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. which the fellows will attend.

The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the spring of 2025, though some flexibility with the start date might be possible.

The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are looking to recruit 6 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. which the fellows will attend.

The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the spring of 2025, though some flexibility with the start date might be possible.

People living with type 2 diabetes are twice as likely to develop heart disease or stroke than those without diabetes, yet the precise mechanisms for this increased atherosclerosis risk remain poorly understood. This translational postdoc project aims to shed light on the links between diabetes, obesity and the associated heightened risk for atherosclerosis by exploring the differential effect of local adipose tissue surrounding larger vessels (perivascular fat) and the systemic impact of the subcutaneous adipose tissue, which represents around 80% of the human fat mass. The project will explore both known disease pathways such as Arginase activity and identify novel mediating factors affecting vascular function by collecting paired clinical fat biopsies and performing molecular and functional analyses. The results can potentially have large implications for our understanding of the interconnection between diabetes and cardiovascular risk, and help identify valuable therapeutic targets for future protective treatments for this extra vulnerable patient group.

We are looking for a motivated postdoc to be part of our research group with a focus on mixture toxicology at the Unit of Biochemical Toxicology, Institute of Environmental Medicine (IMM). The position is placed in the research group of Kristian Dreij, under the supervision of principal investigator Marcos Felipe de Oliveira Galvão in a project that aims to assess acute health effects due to biomass smoke from wildfires.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a Swedish doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

The Integrative Physiology research group at the Department of Molecular Medicine and Surgery at Karolinska Institutet is seeking a highly motivated postdoctoral researcher to join the group of Professor Juleen R. Zierath. The research in the group is focused on translational studies on cellular and molecular mechanisms underlying insulin resistance and type 2 diabetes and the effects of physical activity on glucose and lipid metabolism in skeletal muscle.

This project is designed to test the role of signal transducers to improve glucose homeostasis by targeting skeletal muscle glucose transport. The candidate will explore the molecular signal transducers involved in the regulation of glucose transport to restore glucose uptake in skeletal muscle from people with type 2 diabetes. The team has identified several candidates that may play a direct role in glucose transport. The postdoctoral fellow will validate the role of novel signal transducers in the regulation of glucose transport and insulin sensitivity using knock-down and over-expression approaches in primary human skeletal muscle cells. Promising candidates will be further validated in in vivo models of type 2 diabetes through electroporation approaches.

The work will include comparative effectiveness research, with an emphasis on causal inference methods for complex longitudinal data from both observational studies and randomized trials. The research will be based on data from Swedish population and health data registers, health care quality registers and registry-based randomized clinical trials. Cutting-edge causal inference methods will be applied to motivating use cases in cardiovascular research and other areas. The Postdoctoral researcher will conduct day-to-day project activities, such as writing of protocols and detailed analysis plans, performing data management, conducting analyses, preparing reports on analytical results, presenting findings at project meetings and contribute to drafting of manuscripts. The Postdoctoral fellow will be working together with Drs. Miguel Hernán, Anita Berglund and Anthony Matthews and other members of the team. The positions are for 2 years, with a possibility of extension.

We are seeking one or two postdoctoral researchers with strong motivation to map new aspects of the interplay between chronic pain and the development of cardiovascular diseases. The position involves conducting research in Johan Ärnlöv’s research group at the division of Family Medicine and Primary Care, as well as collaborating with Swedish and international pain researchers. The project has two parts: one focused on traditional cardiovascular epidemiology, examining the relationship between different types of pain exposure and the development of cardiovascular diseases in large Swedish and international study materials, and another with a more molecular biological focus, using large-scale measurements of metabolites, proteins, genes, and microbiota to find new mechanisms behind the links between pain and cardiovascular disease.

Moreover, the successful candidate is expected to play a role in grant applications, doctoral students supervision, teaching to undergraduate and graduate students, and in the expansion of the current research line.

We are looking for a highly motivated candidate with a Ph.D. or equivalent degree in the fields of cell biology, molecular neuroscience, neuropharmacology or neuroendocrinology. Documented experience in working with cell cultures (primary cells, cell lines, iPS models), including their genetic manipulation and experience with the genetic analysis of protein function in mouse models will be required. Practical knowledge in measuring vesicle neuropeptide/hormone transport and release will be seen as necessary. Excellent communication skills in English (both written and oral), and an ability to interact socially and scientifically in a multinational environment will be required. Prior involvement in international consortia or collaborations will be deemed an advantage. A strong publication record will be considered as an important merit during the selection process.

To be eligible for employment as a postdoc a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are looking for a candidate that has the required background and the capability to work in a multidisciplinary team, to be independent and able to take initiatives as well as to find solutions proactively. The applicants must also possess good organizational skills, attention to detail, and communication abilities.

We seek a curious, highly motivated, and creative postdoc with a strong background in stem cell biology. The ideal candidate should have experience working with mouse models and programming languages to analyze sequencing data. Experience with organoid cultures, molecular biology, next-generation sequencing, and large-scale bioinformatics analysis is a strength. Excellent interpersonal and communication skills (in English written and verbal) is required. Emphasis will be also placed on personal suitability, fitting well into the current research group.

We are seeking an ambitious scientist with a background in molecular biology and/or biochemistry. Experience from the chromosome organization and stability field, genome-wide analyses of chromosome organization and/or bioinformatics is considered as an advantage.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

 

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral Researcher to the Department of Pathology

Deadline : 13.Aug.2024

View details & Apply

 

We are seeking an ambitious postdoctoral fellow with great team-working and communication skills, who has a background in either vascular biology (preferably small vessel diseases/CADASIL), and/or neurodegenerative diseases. The successful applicant should have extensive experience and practical skills from research animal work, immunohistochemistry and regular protein and RNA analysis methods such as western blot, qPCR, ELISA, MSD and cell-and molecular biology techniques. Furthermore, it is a merit if the applicant has knowledge in Bioinformatic tools such as in R coding language, and data processing using different package such as the Seurat package, ClusterProfiler, Monocle3. Good ability to speak and write English is a requirement. A strong scientific drive is expected, documented with a publication record.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

We are looking for a highly motivated, driven, and enthusiastic person sharing our interest in inter-disciplinary research and is ready to explore new avenues in science. The candidates should have a collaborative approach to science, a high degree of independence, but also being able to effectively work in an inter-disciplinary team. We value a postdoc that contributes to a good social environment.

• Candidates with a PhD degree from a wide spectrum of disciplines (e.g., neuroscience, psychology, computer science) are encouraged to apply.
• The applicant shall have expertise in data analytics (e.g., statistics, math, artificial intelligence, machine learning).
• Candidates with previous experience with neuroimaging analytics (e.g., EEG, MEG, MRI, PET) on humans or animals, and/or bioinformatics will be prioritized.
• Candidates with coding/programming expertise (e.g., MATLAB, Python, bash scripting, R) will be prioritized.
• Expertise with multivariate statistical methods and machine learning are significant merits.
• Fluency in English is a requirement.

We also attach great importance to personal suitability. 

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a Swedish doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

I rollen som postdoktor kommer du att arbeta i flera projekt med inriktning på arbetsmiljö och hälsa med en genusteoretisk utgångspunkt. Framför allt kommer du att arbeta i en studie med kvalitativ ansats som syftar till att undersöka, utifrån ett genusperspektiv, personliga assistenters och deras arbetsgivares upplevelser av underlättande och hindrande faktorer för återgång i arbete efter sjukskrivning på grund av psykisk ohälsa. Arbetet innefattar datainsamling genom kvalitativa intervjuer, och utförandet av analys (reflexiv tematisk analys). Du kommer även att medverka i författandet av vetenskapliga artiklar och förväntas delta i arbete med gemensamma bidragsansökningar. Tjänsten innebär även att delta i undervisning och bidra till forskargruppens utveckling i stort. Anställningen är en tvåårig visstidsanställning.

We are looking for highly skilled and motivated candidate who is interested in applying new technologies and tools for understanding the mechanisms underlying autoimmune diseases.

• The applicant should hold a PhD in medicine, immunology, biotechnology, or other relevant area.
• Experience in cellular and serological immune assays, flow cytometry and molecular biology.
• Previous research of translational nature within immunology and mice handling is strongly meritorious.
• Fluent oral and written communication in English, and ability to communicate in Swedish at basic level.
• Excellent communication and collaboration skills are of utmost importance, as the successful candidate will work closely with fellow researchers and partners from the clinic and patient organizations.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a Swedish doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are looking for a postdoc who will work in different projects about sickness absence in different life situations, ages, and occupations. The position involves participating in, planning, and conducting studies based on register data. Your duties will primarily involve analysing data, some data management, and writing manuscripts and grant applications.

We seek a highly motivated, creative, and scientifically curious team player with a keen eye for biological intricacies. The ideal candidate should hold, or soon obtain, a doctorate in molecular/developmental biology acquired within the last two years outside of Sweden. Prior engagement in developmental and vascular biology, along with experience in confocal microscopy, image analysis, in vivo experimentation, tissue culture, cell signaling, cloning, and bioinformatics, would be advantageous. Strong communication skills and proficiency in English, both spoken and written, are essential.

We are looking for a highly motivated, driven, enthusiastic person interested in our area of research, and ready to explore new avenues in science. The candidate should have a strong collaborative approach to research, be a team player as well as capable of performing independently and contribute to a good social environment in the laboratory. The candidate must have a PhD in medical sciences, biochemistry, molecular biology or equivalent.

We invite applications from outstanding Ph.D., MD, or MD/Ph.D., candidates with a strong background and profound knowledge in oncology-immunology, immunology, or immunotherapy. We are interested in individuals with a good track-record in the mentioned fields. The candidate should be creative, highly motivated, and aims to establish world-leading research with a clear focus on the field of immunotherapy against cancer impacting potential clinical values and patient outcomes.