28 Postdoctoral Fellowship at Lund University, Scania, Sweden

The tasks include participating in research projects focusing on molecular imaging of metabolic processes in healthy and pathological cells, as well as developing methodological aspects within the metabolic field. The work will encompass clinical and biomedical projects and may also include technology development aimed at integrating experimental techniques in the metabolic field with data analysis to provide a more comprehensive view of molecular processes related to health and disease.

The position is located at the Division of Mathematical Physics, which is a common division between both the Natural Science and Engineering (LTH) faculty, and it is part of the Department of Physics. Presently, the Division of Mathematical Physics hosts five full professors and six lecturers. Research is conducted primarily in the field of quantum mechanical many-particle physics. Specifically, the research areas at the Division include ultra-cold atomic quantum gases, theoretical nuclear structure physics, nanostructure physics, quantum information theory, atomic theory and materials modelling. The division has numerous collaborations both internationally and within Lund University. The team where this position is located was recently associated with the Wallenberg Centre for Quantum Technology (WACQT) and is part of the strategic research priority areas of NanoLund as well as Light and Materials at Lund University.

The work will specifically be carried out in the cold atoms theory group led by Professor Stephanie M. Reimann, which belongs to the Faculty of Engineering (LTH) and is located at the Department of Mathematical Physics. Synergistic effects through our existing collaboration networks, both nationally and internationally, create a strong connection between experimental and theoretical work on ultracold atomic quantum systems. This position is supported by funding from the Knut & Alice Wallenberg Foundation.

You will be based at the medical faculty in Lund. The group for molecular enzymology is located at the Biomedical Center (BMC) at Lund University and is led by senior lecturer Vasili Hauryliuk.

You will have good access to state-of-the-art facilities both within the medical, science and engineering faculties and access to state-of-the-art scientific facilities in Scandinavia and Europe.

A highly motivated postdoctoral scientist is sought to work on a project designed to extend our understanding of the molecular basis of aquaporins (AQPs). AQPs are evolutionary conserved transmembrane proteins that are responsible for water and glycerol regulation in the human body, but also in many other organisms. Besides solute transport, AQPs have been shown to be involved in cellular signaling, cell migration, and cell-cell adhesion. For instance, AQPs are the main glycerol channel in the endocrine pancreas, mediating rapid flux of glycerol in β-cells and ultimately insulin secretion. Interestingly, it was also recently reported that AQPs in fruit flies have a central role in metabolism. The overall goal of the project is to study the structure of aquaporins using single particle cryo-EM and combine that with functional studies at the cellular level to resolve its mechanism of action. In addition, AQPs are therapeutic targets, thus the project will also include the development of putative AQP blockers, that can be used for treating diseases and/or to selectively kill insects expressing aquaporins.  The project will have good access to state-of-the-art facilities within the medical, natural science and engineering faculties, as well as being located in close proximity to the nearby MAX IV synchrotron where also the Lund cryo-EM facility is situated.

This post-doctoral position is part of the EU cofund research project AMBER, Advanced Multiscale Biological imaging using European Research infrastructures, will address scientific and sectoral gaps in biological imaging ranging from molecular, through cellular, to tissue, organ and organism levels of organisation, and is coordinated by LINXS Institute of advanced Neutron and X-ray Science.

AMBER is funded by the EU Marie Skłodowska-Curie (MSCA) COFUND scheme.

Around 10 postdocs will be recruited in the Third call 2024, with each fellowship lasting 36 months.

AMBER has six core partners: Lund University/MAX IV, Sweden, the European Spallation Source (ESS), Sweden, the European Molecular Biology Laboratory (EMBL), Institut Laue-Langevin (ILL), France, the International Institute of Molecular Mechanisms and Machines, (IMOL), Poland, and the Leicester Institute of Structural and Chemical Biology, United Kingdom.

Your work may include clinical and biomedical projects. It may also include technique development work aimed at combining imaging techniques and data analysis to provide a more integrated picture of life processes in the context of health and disease. To be a postdoc fellow at the AMBER programme you will get unprecedented medical, biological, and methodological capabilities, with a profound potential impact for Europe’s next generation of research and researchers. When you have completed the AMBER programme you will be extraordinarily well equipped to further your career in academia, at infrastructures, in the health and MedTech sectors, and beyond.

A highly motivated postdoctoral scientist is sought to work on a project designed to extend our understanding of the molecular basis of transthyretin amyloidosis Read more here. Human transthyretin (TTR) is a protein that transports thyroxine and retinol-binding protein (RBP) in the serum and cerebrospinal fluid. Wild-type TTR is intrinsically amyloidogenic, but a large number of TTR mutants have been identified that are associated with early-onset amyloidosis and where there are remarkable tissue specificities.  This project seeks to gather atomic/molecular level information  on different TTR mutants using crystallography (X-ray and neutron), cryo-EM, and a wide range of other biophysical techniques. It will make use of the MAX-IV and ESS facilities in Sweden as well as the ESRF and ILL X-ray/neutron sources in Grenoble, France. Where possible it is planned  to carry out comparative studies of amyloid material derived from in vitro and ex vivo sources. The project will have good access to state-of-the-art facilities within the medical, natural science and engineering faculties, as well as being located in close proximity to the nearby MAX-IV synchrotron and ESS neutron beam facilities on the Science Village campus near the Lund city centre.

The membrane protein structural biology group at the Department of Experimental Medical Science is at the forefront of its field. With this position, we aim to deepen our work in understanding the mechanisms of various P-type ATPases. The research group is led by senior lecturer Pontus Gourdon, and we are now seeking a motivated postdoctoral researcher with experience in cryo-electron microscopy. 

MAX IV is looking for a postdoctoral candidate for the EU project RIANA.
RIANA is a project under Horizon Europe, aiming to advance research in the fields of nanoscience and nanotechnology. 69 European research infrastructures have joined forces to create a unique platform to cover the most advanced techniques relevant for synthesis, nanofabrication, processing, characterization, analytics, and simulations for advancement in nanoscience and nanotechnology. You will be responsible for supporting user projects in this field with SAXS/WAXS (both transmission and grazing incidence) as a part of a group of junior scientists within the project. The RIANA project is a great opportunity to build up a network within other research infrastructures and an opportunity to learn about other techniques.

The postdoctoral position will be within the AI-Tomo project funded by the Swedish Research funding agency, Vinnova. The project has been established to support and develop the exploitation of machine learning tools to accelerate the analysis of tomography data at the MAXIV synchrotron facility. Synchrotron facility MAXIV (maxiv.lu.se) is a world-leading facility for materials research located in Lund. There are currently three beamlines offering X-ray tomography. The project is a collaboration between the Department of Solid Mechanics at Lund University, MAXIV, RISE (Research Institutes of Sweden), Tetra Pak and Billerud.

You will carry out research and development activities relating to the development of 3D/4D image quantification methods and pipelines using machine learning tools. 

The employment will be at the Department of Solid Mechanics at Lund University, and the work will be carried out in collaboration with RISE, MAXIV, Tetra Pak, and Billerud.

The postdoc will leverage existing high-throughput data from large scale cohorts and large family cohorts complemented with bulk and single cell RNAseq data from relevant tissues to investigate T2D pathogenesis and its early life programming. Read more about the research here (https://portal.research.lu.se/en/persons/rashmi-prasad)

We are looking for one researcher in history of knowledge (100 % in 3 months), with a focus on the Europeanisation of the universities. You will be part of the Lund Centre for History of Knowledge and work within the project “The Europeanization of the Universities: Transforming Knowledge Institutions from within, c. 1985–2010” under the direction of Professor Johan Östling. You are expected to complement the other researchers in the project in terms of expertise and specific focus. 

The postdoctoral position is linked to a sub-project in a larger research project, funded by the Swedish Agency for Contingencies (MSB), with a focus on preventive measures against antagonistic use of dangerous substances in the public environment.
In the project, special focus will be placed on the use of radioactive substances and the radiation protection issues that arise for the public and personnel in connection with the suspected spread of radioactivity. In collaboration with the Total Defense Research Institute, the postdoctoral researcher must develop methods to be able to demonstrate with various physical detection possibilities whether personnel and the public in a public environment have been exposed to ionizing radiation, as well as by measuring these detectors to validate the model calculations to be produced by FOI. The detection methods are linked to what are internationally referred to as folk dosimeters and citizen science, and which have been applied in e.g. in Japan after the Fukushima accident in 2011.

The project will include close collaborations with colleagues in the Total Defense Research Institute in Umeå, as well as in Örebro University.

Cyanobacterial blooms pose a serious health and environmental hazard in surface waters around the world because they produce algal toxins, especially microcystins, which are toxic to humans, wildlife and livestock. This is particularly problematic for surface waters used as drinking water sources. Unfortunately, there is a lack of reliable tools to monitor and predict which factors can lead to high toxicity. The reason is that blooms are composed of strains that produce microcystins and those that do not. The aim of this research project is to determine which factors drive the toxicity of algal blooms and ultimately use this knowledge to develop an early warning system. The approach will involve both field and laboratory experiments. The project includes developing a method that can provide early warning to drinking water producers and other stakeholders of toxic algal blooms. The project is being run in collaboration with personnel at the drinking water producer Sydvatten AB.

The project you will work on aims at developing high-power ultrasonic devices driven by lead-free piezoelectric materials. Lead zirconate titanate (PZT) has been the dominating driving source of high-power ultrasonic devices due to its excellent piezoelectric properties and mature fabrication techniques. However, PZT contains a high content of lead (~60% in mass), which may cause severe environmental issues and is consequently on EU’s Restriction of Hazardous Substances (RoHS) Directive list of materials to be phased out. In this project, you will investigate the possibility to replace PZTs by lead-free piezoelectric materials in high-power ultrasonic devices without sacrificing their performance. Your research work will primarily focus on the construction of high-power ultrasonic devices and the experimental characterization of those devices. You will also develop a theoretical or a numerical model taken into account the nonlinearity under high-power conditions. You will communicate with the material scientists in both industry and academia. 

 

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Post-doctoral position in physics with focus on ultrafast laser diagnostics

Deadline :31.Jan.2025

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The person in charge of the position is Prof Vanya Darakchieva at the Division of Solid State Physics. Vanya Darakchieva has extensive experience in the development of new semiconductor materials for high frequency and power electronics. The research also focuses on developing spectroscopic techniques to study electronic and transport properties of materials from bulk to nanoscale.

A specific direction to be further developed is to investigate electron spin resonances with the THz ellipsometer, so-called high field EPR. It involves the development of equipment and strategies based on polarisation optical methods and aims at defect characterisation in semiconductors. The development is mainly basic research, but has strong links to future quantum technology concepts.

Private international law consists of legal norms which regulate relationships between international private legal subjects which are based on voluntary legal acts. The topic carbon capture and storage (CCS) is at the crossroads of law, governance, sustainability and technology and involves subjects of both public and private law.Transboundary alternatives for CO2 transport and offshore storage are necessary preconditions for the viability of CCS. Once the carbon is captured, the transportation (national and transboundary) can take place by road, rail, ships or pipes.

The post-doctoral position is situated within the project titled “Sustainable Carbon Capture Transportation and Storage: Liability and Governance in Light of International and EU Law.” It addresses the emerging practise of mitigating greenhouse gas emissions through innovative CCS technologies. With a special focus on the transportation of carbon streams by ships, the project relates to the potential liabilities arising during carbon transportation by ship and the implications for long-term liability.

At the Division of Combustion Physics a postdoc is now recruited for the European Union Project CAIPIRINH3A. The main goal of the research performed at our Division within this project is to provide a detailed kinetic mechanism and perform reliable modeling studies for NOx prediction and control in NH3 combustion applications. Experimental results used to validate the numerical model will be based on flame structure measurements of NH3 flames at atmospheric pressure employing Raman spectroscopy arranged with multiple laser beam passages for high detection sensitivity, as well as time-resolved optical emission spectroscopy from ammonia flames after a single pulse nanosecond discharge. The validated mechanism will be incorporated in dedicated global solvers (incorporating plasma effects) which will be used to calculate fundamental combustion characteristics of ammonia/air mixture with and without plasma. The kinetic model will be tested against results from these experiments, other results obtained by the project partners and literature data and will output different characteristics of NH3 combustion including burning velocities, ignition delay times, species profiles in flames, chemiluminescence in thermal and plasma-affected flames.

This project introduces silicon substrates with a switchable magnetic contrast layer (MCL) for polarised neutron reflectometry experiments (PNR) at solid/liquid interface to study soft matter surface layers. The structural and compositional information in a typical reflectometry experiment are obtained by collecting experimental data with different isotopic contrasts on the same sample. This approach is normally referred to as contrast matching, which can be achieved by using solvents with different isotopic contrast, e. g. different H2O/D2O ratio, and/or by selective deuteration of the molecules. However, some soft matter systems might be perturbed by this approach, or it might be difficult to implement, particularly in the case of biological samples. Here solid substrates with a MCL are an appealing alternative, as the magnetic contrast with the substrate can be used to partially recover the information on the sample structure. The project is part of a larger collaborative project, “Maximizing information content in neutron reflectivity data by optimised magnetic reference layers” between Linköping, Uppsala and Lund universities, Science and Technology Facilities Council, ISIS Neutron and Muon Sourcs, Rutherford Appleton Laboratory in UK and European Spallation Source – ESS, financed by the Swedish Research Council.

The overarching theme of this project is to get ready for LDMX data, and the work will be conducted in close connection with the international LDMX collaboration, in which Lund University is the only non-US participant for the time being. One exciting milestone for LDMX is a beam test planned at SLAC in 2025, for the first time collecting data at the actual beam line for LDMX. During the first year, roughly, this project will be focused on the gathering and in particular on the analysis of this test beam data, mainly from the prototype of the hadronic calorimeter.

Another priority in this project will be to study the capabilities of LDMX to handle pile-up (multiple electrons hitting the target at the same time) in more detail. This will mainly be based on simulations studies of potential backgrounds, detector performance, and physics sensitivities. One concrete example is the use of different codes for simulating critical backgrounds, to compare these predictions and to develop methods for how to measure these backgrounds in data. The project also aims to explore to which extent machine learning methods can help with these tasks, e.g. object reconstruction and signal vs background discrimination. This will become more of a focus  later in the project.

There is some flexibility in the research programme for this position, and details can be tailored to your specific interests and expertise. There will also be the opportunity to work with questions of climate sustainability in LDMX/HEP, if that is something you are interested in.

The work focuses on the development of genomic tools to study single protist cells. Some of the planned methods include anaerobic cultivation, environmental sampling, 18S metabarcoding, metagenomics, bioinformatics and phylogenetic analysis.

You will work with the continued development, validation and use of genome engineered pluripotent stem cell based models of Alzheimer’s disease. The work includes both development of new models as well as using established models to study the role of glial cells in Alzheimer’s disease.

The Acoustofluidics Group at the Department of Biomedical Engineering mainly focuses on the emerging field of combining ultrasonics and microfluidics for particle and fluid manipulation in micro- and nanoscale, and it is one of the world-leading groups in this field. The interdisciplinary research carried out in the group ranges from theoretical work in acoustics, fluid mechanics and multibody dynamics to the applications in biomedicine. The group consists of a diverse range of researchers, from senior professors to junior PhD students. The group strives for an inclusive environment, based on collaboration and trust, where development towards an independent researcher is encouraged and supported. More information can be found on the website: Nanobiotechnology and Lab-on-a-chip.

The central aim will be to comprehensively characterize structural breakdown of pea proteins during in-vitro digestion. The specific tasks span from laboratory practices (preparation of an in-vitro digestion scheme for extracted pea proteins, characterization using size-exclusion chromatography (SEC) and gel electrophoresis (SDS-PAGE); biochemical assays) to advanced structural analysis using small X-ray scattering (laboratory SAXS, time-resolved SAXS, SEC-SAXS).

In particular, an important part will be preparation and conductance of experimental campaigns at synchrotron facilities such as MAX IV (Lund), DESY/EMBL (Hamburg, Germany), and ESRF (Grenoble, France), the establishment of a suitable data analysis framework (python-based) targeted at the measured big data sets, and subsequent scientific analysis and interpretation.

The candidate will study the role of the softness of an individual colloid on the structuring and macroscopic properties of a suspension under flow. Suspensions of microgels (soft deformable colloids) will be studied by combining small-angle x-ray and neutron scattering to probe both the particle-to-particle arrangement and the shape of the individual colloid. We will optimise and realise two shear cells, one to probe small-angle scattering (SAS) in the flow-plane, the optimal plane to observe deformations of a material, and the second to probe high applied shear (>10⁴ s^-1). The cells might also enable simultaneous polarised microscopy, rheology and SAS experiments. Microgel suspensions are a textbook example of complex fluids showing fluid-to-crystal transitions, shear thinning, shear banding and the possibility to form glasses or jammed systems. These phenomena are common to most soft materials, both synthetic and bio-relevant, such as protein suspensions, saliva, and blood. SAS experiments in the flow plane and at unprecedently high shear rates will allow us to identify the key parameters in the softness of a colloidal particle that affect the flow properties of the suspension and the role of particle softness on the formation of bands that flow differently. The knowledge developed in this project will pave the way to the design of soft colloids for bio-medical applications, emulsion-stabilized formulations of cosmetics, detergents and shampoos.