36 Postdoctoral Fellowship at University of Cambridge, United Kingdom

This part of an ongoing joint project with the experimental group of Prof Paddy Royall (EPSCI, Paris) and with Prof Tanniemola Liverpool (University of Bristol). The numerical results will be compared with particle-resolved experiments on colloidal systems, using super-resolution confocal microscopy. Dr Jack has a joint appointment between the Department of Chemistry and the Department of Applied Mathematics and Theoretical Physics ¿ the successful candidate will have opportunities to work with other researchers in both departments.

Candidates should have (i) a PhD (submitted or nearly submitted at the time of application) in a field relevant to the interface of agricultural economics, public policy, economic geography, and public health OR (ii) have an established professional career that interfaces the fields of agricultural services, landscape management and public health, and are interested in obtaining a PhD alongside their employment at the CLR. For both groups of applicants, experience with quantitative social science research, mixed-methods research and public policy analysis is desirable. Applicants should provide evidence of potential for research and publication at the highest level, as well as a strong interest in engagement in empirically-grounded, quantitative, and multi-disciplinary policy research.

The project combines behaviour, electrophysiology, optogenetics, chemogenetics, and calcium imaging across the visual system and the hippocampal/parahippocampal network, using the mouse as an animal model. The postdoctoral researcher will join a supportive and multi-disciplinary research environment, collaborate with computational neuroscientists, and closely interact with experts in the fields of visual processing and spatial navigation.

A postdoctoral Research Associate position is available within the Genomic Disorders and Cognitive Development programme at the MRC Cognition and Brain Sciences Unit. The programme takes an interdisciplinary approach to characterising phenotypes and understanding mechanisms in neurodevelopmental disorders of known genetic origin.

 The rationale behind this project is that the ability of nematodes to cause disease depends on hundreds of “effectors”: molecules delivered into the plant during infection. Blocking effectors blocks parasitism, however, blocking individual effectors is insufficient. Rather, we should attack the features that unite most effectors in their biogenesis machinery. Effectors have to pass through a specialised secretory conduit to get into the plant. Surely, this “effector biogenesis conduit” is the Achilles heel of the nematode.

The Research Associate will work on different workshops delivery, reporting, sharing teaching and research related tasks, overseen by Dr Habib. The post will be located in the Centre of Resilience and Sustainable Development at the Land Economy Department. It is led by its Founding Director Dr Nazia M Habib, with an esteemed group of Fellows who are both academics and professionals. The Centre is known for its work on applying systems thinking approaches to political economics theories and developing action-methodologies that can improve the decision-making process.

Duties include developing and conducting individual and collaborative research objectives, proposals and projects. The role holder will be expected to plan and manage their own research and administration, with guidance if required, and to assist, if needed, in the preparation of proposals and applications to external bodies. You must be able to communicate material of a technical nature and be able to build internal and external contacts. You may be asked to assist in the supervision of student projects, the development of student research skills, provide instruction or plan/deliver seminars relating to the research area.

We are seeking a candidate with PhD-level experience in one or more of (i) culturing marine organisms, (ii) measuring the physiology of marine organisms at a fine scale, (iii) measuring and interpreting the transcriptome of marine organisms. The research will involve lab- and field-based experiments, and use measurement equipment across the University (notably the Cambridge Advanced Imaging Centre and the Wellcome-MRC Institute of Metabolic Science). All necessary training will be provided, and the candidate will be mentored and supported in developing their career and research interests. The logistical constraints of the research will require the successful candidate to be based in Cambridge.

The Post-doctoral Research Associate will employ the 10Be synchronization results to generate high-resolution records of ocean ventilation and deep-water flow from marine sediment cores from the Nordic Seas and northern North Atlantic over the last deglaciation. The successful candidate will have experience in many of the following areas including planktic and benthic foraminiferal speciation, stable isotope analyses, preparation of foraminifera for radiocarbon analysis, sortable silt grain-size analysis, age-depth modelling. The essential duties of the position are i) preparation of marine sediment samples for foraminiferal-based geochemical analyses, ii) speciation of foraminiferal samples, iii) conducting radiocarbon measurements with the mini carbon dating system (MICADAS). Other proxies and/or duties may be added during the project and the Post-doctoral Research Associate will be expected to actively participate in data processing and interpretation. The project will ultimately improve our understanding of the relative phasing between abrupt climate shifts and changes in NADW and AMOC strength during the last deglaciation.

The position is full-time. Candidates must have a PhD in a related field. Strong analytical, communication, and organizational skills are also required. The University of Cambridge is one of the world’s leading universities, and the Department of Pathology is renowned for its research in the field of molecular biology. The successful candidate will have the opportunity to work in a dynamic and supportive environment, and to collaborate with leading researchers in the field. This opportunity is funded by the BBSRC, a major funding body for research in the life sciences in the UK, providing support for research and training in universities, research institutes and other organizations.

We are looking for a postdoctoral research associate who would be the key person to work on mechanisms of self-organization and embryo plasticity. The role holder will be able to design, set up and run experiments in consultation with the Principal Investigator, ensuring that they are appropriately supervised and supported; record, analyse and write up the results of experiments, maintaining a permanent record of the methodologies and the experiments; as well as present research outcomes at departmental, national and international conferences. The successful candidate will contribute to the writing, submission and revision of papers, assist with animal colony management and contribute to the overall activities and administration of the project and team.

Candidates should have a PhD in cellular physiology, neuroscience or pharmacology. The successful candidate will be responsible for applying patch-clamp electrophysiology, super-resolution and lightsheet microscopy techniques to investigate and analyse electrical and calcium signalling during invasive growth and motility, working with 3D cultures and organotypic tissue cultures. The candidate should have extensive experience of patch-clamp recording and ion channel physiology and strong numerical and programming skills. They should be motivated to understand how cancer cells take advantage of neuronal signalling mechanisms and interactions with neurons during cancer progression.

To apply for this post, please submit a CV, and a motivation letter detailing why you want to be part of this project and how this post will be a good stepping-stone for your career. We also need the contact details for two people who can provide a professional reference. The closing date for the applications is 15 March 2023. The start date will be in April or May 2023.

The MRC Biostatistics Unit is currently offering an exciting biostatistics position in the University of Cambridge. This appointment will be made at Research Associate level and would be working on both the implementation of a novel adaptive design and the analysis of the Stratosphere trial (led by Dr. Mark Toshner): a Phase II trial in Pulmonary Hypertension. The post will be part of a team of statisticians working with Dr. Sofia S. Villar and Dr. Nina Deliu. Additionally, there will be lots of opportunities to interact and collaborate with researchers in our theme as well as other researchers in the MRC Biostatistics Unit, Papworth and Addenbrookes Hospital and international collaborators. The post offers the opportunities and challenges to develop and apply novel methodology in practice to a first of its kind study!

 

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title:    Research Associate (Fixed Term)

Deadline : 31 March 2023

View details & Apply

 

The MRC Epidemiology Unit is a department within the University of Cambridge’s School of Clinical Medicine and is situated within the Institute of Metabolic Science on the Cambridge Biomedical Campus. Its mission is to study the genetic, developmental and environmental factors that cause obesity, diabetes and related metabolic disorders and develop strategies for their prevention. The Unit consists of eight scientific programmes and this post will be based in the Prevention of Diabetes and Related Metabolic Disorders group, led by Professor Simon Griffin. The Unit benefits from a number of large-scale, cross programme epidemiological studies and randomised controlled trials, with detailed datasets allowing a wide range of research from genetics to public health. Highly experienced information teams and other specialist teams support the scientists in the delivery of their research aims.

The Markowetz lab is a mixed computational/experimental lab with a strong track record in machine learning working on a broad range of topics in cancer genomics and imaging. It offers a supportive and diverse environment (see: Markowetz, ‘You are not working for me, I am working with you’, PLoS Comp Bio 2015) and has been a jumping board for many successful careers in academia, industry, and spin-off companies. Alumni had the independence to build on their projects and kick-start their careers.

The post holder will be part of a larger travel behaviour modelling team and will collaborate closely with the GIS and health impact modelling team, in particular in implementing in JAVA these parts of the model. The model structure will build up on the integrated open source land use- travel behaviour network assignment model assembled by Professor Rolf Moeckel (TUM, Germany). The aim of the JIBE project is to incorporate both the built environment factors that influence multidimensional travel behaviours and resulting health exposures, behaviours, and outcomes within this model suite.

Essential requirements for this position are (i) a PhD in Chemistry, Chemical Engineering, Materials Science or similar, (ii) PhD-level expertise in chemical/materials synthesis and characterization. Additional desirable skills: (iii) experience with gas adsorption experiments, and (iv) experience with electrochemistry ¿ candidates must have at least one of the two desired skills to be considered. The cover letter should specifically discuss each of these four criteria in turn.

Applicants should have a strong foundation in statistical methods and computational science with a PhD in a computational discipline such as bioinformatics, computational biology/chemistry, computer science or quantitative biology. Previous experience in analysing genomic (especially high-throughput sequencing data) and or other type of biological datasets is highly desirable. Candidates with structural bioinformatics background are also strongly encouraged. For academic candidates a consistent record of strong scientific publications is essential. The position requires strong communication and teamwork skills and involves regular interactions with experimental and computational researchers across Professor Sir Shankar Balasubramanian’s two laboratories based at the CRUK Cambridge Institute (CI) and the University’s Yusuf Hamied Department of Chemistry. The successful candidate will be highly organized, with good time management skills.

The candidate will be joining a diverse and dynamic group consisting of astronomers, computer scientists and engineers working on SKA as well as the SKA precursors and prototypes including eMERLIN. The SKA project is adopting the Scaled Agile Framework (SAFe) for software development and the candidate will receive training to work as part of an agile software development team. Critical areas to be explored are use of scalable data execution frameworks, fast buffering, astronomy workflow development and integration and algorithmic performance.

You will interact closely with the CLR research team, which includes systems engineers, soil scientists, chemists, computer scientists, social scientists, conservationists, and hydrologists working on field-scale water-flow and water-table manipulation through peat and degraded peat soils, GHG emissions (CO2 and CH4) and water quality. You will also contribute to work by CLR’s biodiversity and landscape-scenario modelling teams on the practical and economic feasibility of different water-management regimes.

We are seeking a postdoctoral research associate experienced in a range of molecular and cell biology techniques to lead on projects investigating the molecular basis of thinness. You will be working in close collaboration with other team members, taking a leading role in the cellular characterisation of proteins in which human mutations are associated with thinness. You will have experience of working with CRISPR/gene editing technologies and have experience of working with cells/cell lines/tissues/organs involved in metabolic diseases.

The successful applicant will have experience in the modelling and thermodynamics of geological fluids and solids and either hold a PhD (or equivalent) in physical sciences, engineering, mathematics or similar (or have recently submitted a PhD dissertation in these areas). The applicant will work with researchers in Cambridge developing reference solutions for the CO2 phase behaviour and flow in coupled wellbore-reservoirs for simplified systems that allow exact solutions. An interest in, and familiarity with, flow in porous rocks and geological formations is advantageous. The successful candidate will have a track record of publication in peer-reviewed international journals and will have good communication skills in order to present results at international meetings.

A position for studying mixed conductivity in organic electronic materials and developing more refined models of the physics of organic electrochemical transistors is available. The successful applicant will work in collaboration with collaborators in the Department of Physics to set up and run experiments and drift-diffusion modelling aimed at understanding the interplay between ionic and electronic conductivity in mixed organic conductors. They will make and study organic electrochemical transistors to refine the current model of operation.

Candidates are encouraged to apply if they have a neuroscience background and are keen to study metabolic science and brain-body interactions at a world-renowned institute. Applicants are particularly encouraged to apply if they have experience with either two-photon imaging or electrophysiology, with preference given to those with some in vivo experience. It is not expected that the candidate will have an extensive experience in all the experimental techniques required for the project from the onset. However, it is expected that the candidate has the aptitude, passion, and perseverance to learn new things. The lab recognizes the importance of career development of its members and will provide the necessary training, including in experimental skills and professional development, where appropriate.

The postholder will be responsible for establishing crystallographic platform for fragment-based and structure-guided drug discovery campaign, to validate the binding mode of existing inhibitors and of new hit molecules from our own screens. They will also be performing fragment screens on the target and validate hit molecules using biophysical methods.

Duties include undertaking basic research from start to finish using straightforward mathematical modelling or scientific computation. This process will involve research, contributing to the production of reports and publications, and analysing, interpreting, and writing up your results. You will also need to be confident in presenting this information to steering groups and other bodies and forming relationships with internal and external contacts. You may also be asked to assist in the supervision of student projects or to provide class supervision/instruction.

Duties of the Research Associate(s) include developing and conducting individual and collaborative research objectives, proposals and projects as part of the overall work of the Maths4DL programme. The successful candidate(s) must be able to communicate materials of a technical nature and be able to build internal and external contacts. The successful candidate(s) may be asked to assist in the supervision of student projects, provide instruction and plan/deliver seminars relating to the research area of Maths4DL.

The funding supporting these positions is available with immediate effect for five years in the first instance and in addition to the Group Leader salary will include a 3 year postdoctoral position, a PhD studentship and a start-up budget. The appointment will be subject to the Faculty Board of Clinical Medicine approval. It is anticipated that the position will be in the Department of Oncology, although depending on the area of expertise of the successful candidate, another University Department could be the appointing Department.

The key responsibilities and duties are to provide technical leadership and coordination to the DRF initiative via research advancement in Automation & Robotics within its existing grants; authoring new grant proposals; authoring publications and disseminating the initiative’s outcomes; teaching and learning support; administration, financial management, planning and organisation; staff management, training, and supervising; and internal and external networking, while constantly upholding the university’s values.

It is not envisaged that the role will involve undertaking substantial new fieldwork, but the ability to lead targeted field survey and excavation is desirable. The role is expected to be largely office based, but may involve periods of active fieldwork within the wider Fenland Region. The successful applicant will coordinate with staff at the Cambridge Archaeological Unit and will be based within the McDonald Institute for Archaeological Research. The successful candidate will also be able to take up a position as Fellow of the McDonald Institute and will join a vibrant postdoctoral research community allowing them to participate in seminar and research groups, careers and professional development training, and to be supported by the Institute’s established programme of senior academic mentorship. The successful candidate may also contribute to departmental teaching and learning, and supervise postgraduate students as part of the wider research team. Flexible and hybrid working arrangements are possible subject to discussion with the project’s senior leadership team.