39 Postdoctoral Fellowship at University of Cambridge, United Kingdom

The Department of Genetics at the University of Cambridge invites expressions of interest from early career researchers who wish to be sponsored for external fellowships to establish an independent research group.

Successful candidates will be of the highest calibre, with an exceptional track record for their career stage and the potential to submit competitive fellowship applications. The department will assist with the development of your fellowship application and practice for interviews. If successful, we have a programme of support to establish your independence as an academic researcher, including setting up your lab and recruiting personnel, as well as mentoring and training to help you develop your career. You will also be supported by the Cambridge Biological Sciences Research Fellowships Framework (www.bio.cam.ac.uk/research/research-fellowships) and peer-to-peer mentoring through the early PI network (www.bio.cam.ac.uk/biological-sciences-early-pi-network). You will have group leader status equivalent to tenured staff, playing a full role in running the department and will be given opportunities to gain experience in undergraduate and postgraduate teaching.

The CRUK Cambridge Institute (CRUK CI) invites senior clinicians intending to apply for CRUK Advanced Clinician Scientist Fellowships (or equivalent) to consider basing their group at our institute as Independent Clinical Fellows. Our new programme is specifically designed to support independent fellows become established clinical academics and leaders in their field.

In addition to hosting your research group, our unique programme provides substantial additional support (£50k per year) for use in our state-of-the-art core facilities, administrative support and critical input during your application process and for the duration of the fellowship, as well as mentorship from a diverse world-class faculty of cancer researchers. Your independent group will be provided with generous bench and write-up space in an institution with outstanding research infrastructure and a lively scientific community.

We seek a Postdoctoral Research Assistant / Associate (PDRA) to join a multidisciplinary project “Building Shells: Towards a Mechanistic Understanding of Biomineralisation” funded by the Leverhulme Trust.

The successful candidate will work closely with the PI and a PhD student within a larger cross-disciplinary team to construct a quantitative computational model of carbonate biomineralisation processes.

Carbonate biomineralisation is a key process in global carbon cycling, but there are major gaps in our understanding of how biominerals form. We lack a quantitative understanding that can predict the formation rates or composition of a biominerals from known environmental conditions. This project aims to construct such a model.

Cambridge Judge Business School leverages the power of academia for real world impact to transform individuals, organisations and society. Since 1990, Cambridge Judge has forged a reputation as a centre of rigorous thinking and high-impact transformative education, situated within one of the world’s most prestigious research universities, and in the heart of the Cambridge Cluster, the most successful technology entrepreneurship cluster in Europe.

We are looking to recruit a Research Assistant/Associate to work at the Cambridge Endowment for Research in Finance (CERF) based in Central Cambridge at the University of Cambridge Judge Business School. CERF was founded in 2001 as an independent endowment in the University of Cambridge. The formal objective of CERF is to promote research within the University into all aspects of finance, financial institutions and financial markets, and their relationship with economic behavior and performance.

Cambridge Judge Business School leverages the power of academia for real world impact to transform individuals, organisations and society. Since 1990, Cambridge Judge has forged a reputation as a centre of rigorous thinking and high-impact transformative education, situated within one of the world’s most prestigious research universities, and in the heart of the Cambridge Cluster, the most successful technology entrepreneurship cluster in Europe.

We are looking to recruit a Research Assistant/Associate to work at the Cambridge Endowment for Research in Finance (CERF) based in Central Cambridge at the University of Cambridge Judge Business School. CERF was founded in 2001 as an independent endowment in the University of Cambridge. The formal objective of CERF is to promote research within the University into all aspects of finance, financial institutions and financial markets, and their relationship with economic behavior and performance.

A Postdoctoral Research Associate position is available for 2 years in human 3D organoid-based disease modelling in Amyotrophic Lateral Sclerosis (ALS) in the laboratory of Dr András Lakatos at the University of Cambridge. The exciting wet lab-based research project is at the intersection of basic biology and translational science, incorporated within the UK EXPERTS-ALS platform programme.

The successful candidate will explore the interactions between genomic changes and molecular pathways relevant to early pathologies and the progression of ALS using cutting-edge human CNS organoid models/tissue engineering and patient samples. The research may also involve drug testing in translational in vitro platforms and mechanistic target-engagement studies that inform the clinical trial programme.

We are seeking a Clinical Research Associate wishing to pursue research in the area of automated insulin delivery (closed loop systems) in adults with diabetes. The research is funded by the National Institute for Health Research and other funding agencies. Possession of GMC licence to practise is essential. The post would suit a doctor in training at UK / IMT level or above (or equivalent), wishing to gain experience in clinical and translational research. Postgraduate training in adult endocrinology / diabetes would be desirable for this post, but not essential.

Applications are invited for a post-doctoral research associate to join the group of Professor Chiara Giorio at the Department of Chemistry on a research project aimed at using oxidation products of isoprene and monoterpenes for paleoclimate reconstruction.

The project, funded by Leverhulme Trust, involves atmospheric chemistry box-modelling of the oxidation of isoprene and monoterpenes (e.g., alpha- and beta-pinene) including secondary organic aerosol production and multiphase reactivity. A particular target of the modelling work are the oxidation end-products in the particulate phase and the relationship between the relative abundance of those products in simulations run under different exposure to atmospheric oxidants (e.g., ozone and OH radical). Additional work will include an error propagation analysis to assess the uncertainty to the relationship between oxidation product patterns and oxidant concentrations.

The Department of Plant Sciences is seeking to appoint a post-doctoral Research Associate to join a project on reprogramming plants. The engineered plants will be used to provide unique insights into the biological programs that control root growth in response to nitrogen, and the role of root system architecture in nutrient use efficiency. The successful candidate will join the Patron Lab and will work in collaboration with researchers in the Brady Lab (University of California at Davis, USA) and the Zurbriggen lab (University of Dusseldorf, Germany). We will provide a supportive research environment with an emphasis on personal development, research excellence, integrity, and respect

The Department of Plant Sciences is seeking to appoint a post-doctoral Research Associate to contribute to the discovery and production of bioactive natural products with utility in agriculture. The successful candidate will join the Patron Lab funded by a new Global Centre for the Bioeconomy with collaborators in the USA, Canada, UK, Japan and South Korea. We will provide a supportive research environment with an emphasis on personal development, research excellence, integrity, and respect.

Applications are invited for a Postdoctoral Research Associate position in the laboratory of Prof. Ewan St. John Smith at the Department of Pharmacology, University of Cambridge for an immediate start to work on The Helmsley Trust funded project: New insights into Crohn’s disease from studying Naked Mole Rats.

Inflammatory bowel disease (IBD) affects ~5 million individuals globally. One form of IBD is Crohn’s disease (CD), a condition characterised by the development of inflammation and structural abnormalities throughout the digestive tract, which generally results in diarrhoea and abdominal pain. Increased understanding of disease pathogenesis could lead to improved therapeutic, and perhaps preventative, treatment. Naked mole-rats are extremophile animals that live for 35+ years and maintain good health throughout lifespan. Of relevance to CD, naked mole-rats also show diminished inflammatory pain, and their digestive tract displays reduced permeability, as well as showing disease resistance in a CD-like model.

Applications are invited for a Postdoctoral Research Associate position in the laboratory of Prof. Ewan St. John Smith at the Department of Pharmacology, University of Cambridge for an immediate start to work on The Helmsley Trust funded project: New insights into Crohn’s disease from studying Naked Mole Rats.

Inflammatory bowel disease (IBD) affects ~5 million individuals globally. One form of IBD is Crohn’s disease (CD), a condition characterised by the development of inflammation and structural abnormalities throughout the digestive tract, which generally results in diarrhoea and abdominal pain. Increased understanding of disease pathogenesis could lead to improved therapeutic, and perhaps preventative, treatment. Naked mole-rats are extremophile animals that live for 35+ years and maintain good health throughout lifespan. Of relevance to CD, naked mole-rats also show diminished inflammatory pain, and their digestive tract displays reduced permeability, as well as showing disease resistance in a CD-like model.

The Ali group invites applications for a Postdoctoral Research Associate. Our goal is to understand how the multicellular structure of breast tumours drives relapse and therapeutic response. We characterise the dynamic multicellular structure of human cancers using quantitative tissue imaging (imaging mass cytometry; spatial transcriptomics; digital pathology) and sophisticated image processing1-3.

We are assembling tissue imaging datasets of unprecedented depth and size in both observational studies and clinical trials. This will enable us to unmask spatial phenotypic traits that emerge during disease progression and treatment, and to identify those that drive prognosis and therapeutic response. The main aim of this project is to characterise regulators of an immunosuppressive TME and their impact on immunotherapy response in breast cancer. To address this question reliably, we have generated a novel highly curated dataset using samples from a major breast cancer immunotherapy trial. The project would particularly appeal to computational biologists experienced in TME analysis or a biologist with a strong immunology background and some experience of computational biology looking to significantly build on their skills in a specialised lab.

The post holder will be employed as part of The Productivity Institute (TPI), a UK-wide research organisation exploring what productivity means for business, for workers and for communities ¿ how it is measured and how it truly contributes to increased living standards and well-being. The £32m TPI is being funded by the Economic and Social Research Council (ESRC) as part of its largest single investment into social sciences research. Further information can be found here: https://www.productivity.ac.uk/

The project will explore the association between personal values, motivation, social factors, and economic productivity in the UK. More specifically, it will investigate the extent to which motivations related to work, and underlying personal and social values, have changed over time, and across generations. We will draw on a number of large panel data sets, with the aim to extract insights about the psychological and motivational factors underlying productivity in the UK, incl. how they have been changing over time.

 

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Research Associate (Fixed Term)

Deadline : 25 January 2025

View details & Apply

 

We are seeking a Research Assistant/Research Associate to join an exciting team at the University of Cambridge working with the Prob_AI Hub, a world-leading research programme in probabilistic AI. This £8.5M programme is funded by EPSRC and brings together research groups from the Universities of Lancaster, Bristol, Cambridge, Edinburgh, Manchester and Warwick. Interaction between the research groups at the six universities is strongly encouraged and resourced. The position will also initially contribute to the Machine Learning for Tomorrow research programme which is synergistic to the Hub and involves Microsoft Research Cambridge.

We invite applications for a Research Assistant/Associate position in the Department of Engineering, to work on Probabilistic Machine Learning. The post holder will be located in Central Cambridge, Cambridgeshire, UK.

We seek to appoint an independent researcher to lead a technical research program for effective Human-AI cooperation. This position will contribute to the research programme “Advancing Modern Data-Driven Robust AI”, which is funded by UKRI through a Turing AI World-Leading Fellowship lead by co-investigators Professor Zoubin Ghahramani (Department of Engineering) and Dr Ferenc Huszár (Department of Computer Science and Technology).

We are looking for a highly motivated post-doctoral researcher to help develop and use new models and analyses for landscape conservation aimed at problems of habitat loss, fragmentation, and connectivity, both locally and globally. The project is a growing collaborative effort to provide reliable science for landscape conservation efforts.

Your role in the project is to: 1) apply advanced models to map connectivity globally for terrestrial vertebrates; 2) develop new metrics for interpreting the role of connectivity, habitat loss, and fragmentation for biodiversity and extinction risk; 3) test these models empirically with existing data sets; and 4) engage in applications for conservation.

We are inviting applications from clinicians with an interest and experience in oncology to apply for the CRUK Cambridge Cancer Centre funded Breast Programme Clinical Fellow position. The successful applicant will be embedded within the Precision Breast Cancer Institute (PBCI) and support the development and delivery of innovative clinical trials in patients with breast cancer, focusing strongly on early breast cancer and related translational research projects.

Applications are invited for a Postdoctoral Research Associate to work with Prof. Steven F. Lee (Yusuf Hamied Department of Chemistry, University of Cambridge) in a collaborative project with Prof. Sonia Gandhi (The Francis Crick Institute). The position is generously funded by a philanthropic gift from Robert Martin and comes with a college association at Selwyn College, Cambridge. This project aims to develop a biochemical diagnostic tool for Parkinson’s Disease (PD).

The aim of the project is to create a diagnostic test for Parkinson’s Disease by detecting single protein aggregates, or “oligomers,” in biofluids such as cerebrospinal fluid (CSF), saliva, and blood. These oligomers are small pathological assemblies of alpha-synuclein implicated in the progression of PD. The research will utilise advanced single-molecule imaging techniques, including FRET-based imaging and custom microscopy, to identify and quantify these biomarkers with unprecedented sensitivity and high throughput using microfluidics fabrication.

Applications are invited for a researcher position in the laboratory of Dr Catherine Lindon at the Department of Pharmacology, University of Cambridge. The successful candidate will join a team investigating the mode of action of novel tools for Targeted Protein Degradation (TPD). Small molecule PROTACs harnessing the cellular ubiquitination machinery to destroy targets of clinical importance are at the forefront of a revolution in therapeutic strategies, yet many parameters of the relevant ubiquitination pathways are not well understood.

This study is a great opportunity to gain experience in a novel and rapidly expanding field and to contribute to important and timely research questions about how PROTACs find and ubiquitinate their targets, and what cellular factors modify the success of TPD strategies. This knowledge will feed into therapeutic strategies of the future.

The post holder will work within a programme focused on mitochondrial transport proteins, which are crucial for the functioning of mammalian cells. This project is funded by Apollo Therapeutics and focusses on the development of specific inhibitors of a mitochondrial carrier protein. Thermostability shift and transport assays have already been developed to screen for better and more specific binders. The project involves a collaboration with Apollo Therapeutics and associated Contract Research Organizations as well as with different experts on mitochondrial biology within the MRC-MBU. The post-holder will participate in every stage of the process, including protein purification, screening of novel binders by thermostability shift and transport assays, structural analysis by cryo-EM, interaction with other team members and collaborators, and preparation of manuscripts/IP.

CISL works to develop pioneering ideas, research and resources for better decision-making and system design, including through The King’s Global Sustainability Fellowship Programme. Under this programme, we are seeking to appoint a Fellow on a 12 month fixed term contract (extension subject to available funding). This post will be offered as either a Research Associate or Senior Research Associate dependant on level of qualifications and experience and is funded through a philanthropic donation from Heathrow Airport Ltd.

This role will be closely affiliated with a flagship initiative run by CISL in partnership with Cambridge’s Whittle Laboratory, the Aviation Impact Accelerator (AIA). The AIA’s mission is to accelerate the journey to sustainable aviation by developing evidence-based tools and insight that allow people to map, understand, and embark on the pathways towards sustainable flight.

The Department of East Asian Studies, within the Faculty of Asian and Middle Eastern Studies at the University of Cambridge, seeks to appoint to a 3-year, fixed-term Postdoctoral Research Training Associate in Japanese Studies. The post will start in September 2025 and last until August 2028. This position is designed for early careers researchers and provides mentoring and training in teaching and research to enhance the role holders future career prospects.

We are open to any specialty within the range of fields from premodern to modern Japanese Studies with an expectation of fluency in Japanese, which may include classical Japanese and/or kanbun, is expected. We also welcome applications from candidates who embody our “Japan and the World” campaign and with an interest in comparative studies in relation to the rest of East Asia.

A position exists for a Research Assistant/Associate in the Department of Engineering to support and maintain the University’s national and international reputation for excellence in research and research leadership. The post holder will be located in Central Cambridge, Cambridgeshire, UK.

The research role is to perform research in data assimilation in fluid dynamics, specifically to assimilate steady and periodic Flow-MRI data into physics-based models modelling momentum transfer through (i) a uniform Newtonian viscosity and (ii) a turbulent RANS equation. Periodicity will be ensured with the harmonic balance equations. The research leadership role is to help the PI coordinate the activities of the Hub for the National Fellowships in Fluid Dynamics (NFFDy Hub) and the UK Fluids Network (UKFN).

A post-doctoral Research Associate or Research Assistant position in Cognitive Computational Neuroscience is available to work with Prof Zoe Kourtzi at the Adaptive Brain Lab, Univ of Cambridge, UK (http://www.abg.psychol.cam.ac.uk).

The position will focus on cognitive computational neuroimaging studies of learning and brain plasticity. Our studies combine ultra-high field brain imaging (7T fMRI, MR Spectroscopy), electrophysiology (EEG), interventional (TMS, tDCS) and neurocomputational (machine learning, reinforcement learning) approaches to understand the network dynamics that support learning and brain plasticity.

We seek to appoint a highly-motivated postdoctoral researcher to conduct original research on advanced machine-learning for analysis of photometric and spectroscopic extragalactic survey datasets. The research will prepare the path for the Vera C. Rubin Observatory’s Legacy Survey of Space and Time (LSST). The successful applicant will be part of the European Research Council Advanced Grant CosmicExplorer project, led by Professor Hiranya Peiris at the Institute of Astronomy in Cambridge (www.ast.cam.ac.uk). The position will involve original research in cosmology and/or galaxy evolution using survey data.

A position exists for a Research Associate in the Department of Engineering to work on Automated Performance and Productivity Measurement in Construction. The post holder will be located in West Cambridge, Cambridgeshire, UK. The appointee will design and develop new data integration algorithms and machine learning techniques to integrate construction data for performance and productivity measurement. Leveraging real construction data, the successful candidate will design and develop an on-line dashboard and user interface to present construction data for effective decision-making.

The Institute of Astronomy (IoA), Cambridge University expects to appoint one or more postdoctoral researchers to work with Professor Kaisey Mandel on projects in supernova cosmology, transient astronomy, astrostatistics and/or machine learning. Prof Mandel’s interdisciplinary research group is funded by the European Research Council and spans the Institute of Astronomy, Kavli Institute for Cosmology, and the Statistical Laboratory of the Department of Pure Mathematics and Mathematical Statistics. Appointments to the StatsLab (DPMMS) are possible. Negotiable starting dates from ASAP through to October 2025.

Applications are invited for a Senior Research Associate (Core Service Technologist with a specialist in Neuroscience) to join the Institute of Metabolic Science – Metabolic Research Laboratories with the Clinical School of Biochemistry at the University of Cambridge (https://www.mrl.ims.cam.ac.uk/).

The successful applicant will join the Disease Model Core (DMC) Facility as part of the Wellcome Discovery Platform. The role is a unique opportunity to contribute to the development of cutting-edge research strategies that integrate advanced in vivo neuroscience tools with behavioural, metabolic, and neuroendocrine assessments. You will work closely with the Blouet group and other investigators to innovate and implement protocols addressing metabolic and nutrient sensing circuits under physiological conditions. As part of a core service, you will be encouraged to develop business strategy.

The Pathogen Dynamics Unit, located within the Department of Genetics at the University of Cambridge is looking for one full-time postdoctoral Research Associate to work on projects relating to the emergence, spread and control of dengue virus.

The Pathogen Dynamics Unit at the University of Cambridge consists of 15-20 researchers at different stages of their career using mathematical and computational research to help our understanding of how pathogens spread in populations, assess control efforts and support policy making. We work closely with an established network of collaborators across laboratories, field-based epidemiologists, hospitals and public health agencies.

This is an exciting opportunity to work within the research project titled “Amalgamating Evidence About Causes: Medicine, the Medical Sciences, and Beyond”, led by Professor Jacob Stegenga, in partnership with Professor Stephan Hartmann (LMU Munich), and funded by AHRC & DFG. This full time Postdoctoral Research Associate position with expertise in philosophy of science or medicine is fixed term until 31 January 2027.

In many areas of science, a variety of evidence from different methods, experts, and disciplines can be relied on when inferring causal claims. The amalgamation of evidence to produce causal knowledge is a widespread challenge for scientists and those aiming to rely on causal claims in decision-making. This is acutely important in the biomedical sciences and in medical practice. The goal of the project Amalgamating Evidence About Causes is to systematically study the amalgamation of causal evidence in medicine, by articulating formal constraints, prescriptive principles, and methodological heuristics that could guide practitioners in medicine and could be used as evaluative norms in this practical, policy-oriented context. More information about the project can be found in the Further Particulars.

We seek a Post-doctoral Research Associate to work with Dr Annelies Quaegebeur, Dr Joanne Jones and Prof Roger Barker studying the molecular mechanisms of Parkinson’s disease and “Parkinson-plus” disorders.

The successful candidate will investigate the molecular signatures of disease-associated glia in human brain tissue.

This research aims to identify new molecular targets for treatments and biomarkers for Parkinson’s disease and “Parkinson-plus” disorders. This project draws on our ongoing work into the molecular substrates of neuroinflammation in Parkinson’s disease and “Parkinson-plus” disorders using state-of-the-art spatial omic technologies and is embedded within the international Aligning Science Across Parkinson’s (ASAP) network.

In this project a very wide range of ancient sediment DNA samples from a mixture of agricultural and extreme environments will be sequenced. The resulting aeDNA data will be analysed to help understand genetic and ecological responses to climate change, so as to inform development of more robust agro-ecosystems for the future. The work will involve computational genomics methods development and analysis of large scale but extremely low coverage ancient metagenome data. Specifically, goals include:

• applying and potentially improving methods for efficient processing and taxon assignment of shotgun aeDNA data. One possible opportunity here will be to help construct a new updatable phylogenetically organized sequence index for biodiversity as the number of sequenced genomes increases exponentially.
• for specific taxa of interest, including crops and associated pathogens, building and fitting models of demographic change and selection based on sparse population variation data across time and space, combining aeDNA data with present data genetic diversity.
• identify specific genotypes that have the potential to contribute to ecological robustness, supporting collaboration towards practical translation with AEGIS plugin partners.

In this project a very wide range of ancient sediment DNA samples from a mixture of agricultural and extreme environments will be sequenced. The resulting aeDNA data will be analysed to help understand genetic and ecological responses to climate change, so as to inform development of more robust agro-ecosystems for the future. The work will primarily cover computational biology development and analysis on large scale but extremely low coverage ancient metagenome data, with also occasional field work for sample collection. Specifically, it involves:

• collecting and pre-processing lake sediment and archeological deposit samples.
• using generated aeDNA data (both shotgun metagenomes and capture sequencing data) to reconstruct the early domestication process of crops in East Asia (rice and millet), identifying the traits and genetic variants under selection in the process, and retrieving lost genetic diversity from ancient material.
• developing and applying new computational methods to study the questions listed in 2.

We wish to appoint a Research Associate to design, execute and report the results of real-world data analytic studies in mental healthcare as part of a National Institute for Health and Care Research (NIHR) programme to improve clinical outcomes in people with mental disorders. The aim of the research programme is to develop Real World Evidence (RWE) that will be implemented in clinical practice to reduce treatment delays and improve access to NHS mental healthcare.

The appointee will work with a multidisciplinary team of data engineers, clinicians and data analysts to lead epidemiological research on largescale electronic datasets and generate evidence to improve mental healthcare outcomes.