40 Postdoctoral Fellowship at University of Copenhagen, Denmark

The Department of Food and Resource Economics, Faculty of Science, University of Copenhagen invites applications for a position as associate professor within the field of Political Ecology and Environmental Justice. Climate change and the global struggle over natural resources change the life conditions of millions. The environmental sustainability challenges cannot be understood in isolation from broader dynamics of economic and social development, struggles over access and rights to resources, or conflicts originating from historical grievances. There is a need to understand the material and discursive aspects of environmental change and land-use and resource conflicts. This includes how and why access to and control over resources change and what are the socio-economic and environmental outcomes. We invite applicants who work on these and similar questions whether it be in urban or rural settings, on industrial or smallholder agriculture, or on forest- or land degradation.   

The larger project investigates what it means to feel, think, and act as part of a we. Its guiding hypothesis is that a systematic account of the we must be embedded in a more comprehensive investigation of selfhood and social cognition. The project will systematically develop this hypothesis by combining cross-disciplinary theorizing with historical scholarship. In particular, it will draw on seminal contributions from classical phenomenology. In addition to philosophers, the project also involves social scientists (from social anthropology, sociology, social psychology, and clinical psychology).

We are looking for a highly motivated and dynamic postdoc for a 2-year position (with possible extension) in family and sexual health. The start date is negotiable, but we anticipate Fall 2023.

We seek a highly qualified researcher in the area of Molecular Muscle Metabolism to join the August Krogh section for Molecular Physiology at the Department of Nutrition, Exercise and Sports, University of Copenhagen. The position as Associate Professor is permanent. This is a position for you – if you wish to bring forward new mechanistic understandings to muscle metabolism with relevance for human physiology, – if you wish to work in a state-of-art research environment in which you can perform research from molecules to man and, – if you wish to interact with a range of prominent research colleagues, fellows and students with similar devotion.

We invite highly qualified, thorough and motivated applicants to apply for the position. The postdoc will engage in a collaboration that aims to study the intra- and intergenerational health and labour market implications and costs of divorce among families in Denmark. The postdoc will develop novel statistical methods and apply these to register and RCT data to investigate heterogeneity in effects of divorces and investigate whether subgroups are especially adversely affected by divorce. Specifically, the project aims to develop methods for inference on key features of the heterogeneous effects, to estimate characteristics and differences of the most and least impacted groups, and to data-adaptively identify key drivers of treatment effect heterogeneity. The successful candidate will be responsible for methods development, designing proof of concept simulation studies and carrying out the data analyses. The Postdoc is encouraged and expected to drive the ideas and solutions within these topics.

The position is in the section for Plant Biochemistry which is a world-leading and highly attractive international research environment for scientists, students and industrial partners. The mission of Plant Biochemistry is to produce cutting-edge research, deliver excellent research-based education and training, and encourage entrepreneurship and industrial collaboration. A key research area of the section is the basic science of plant-specialized metabolism. The research area is linked to the Green Transition guiding the development of environmentally benign biobased production systems involving plant-specialized metabolites.

The postdoc will be part of a project entitled Selection in Cognition funded by the Carlsberg Foundation and headed by Professor Søren Kyllingsbæk and Associate Professor Thor Grünbaum. Applicants are asked to situate and develop their research plan within the framework of the Selection in Cognition project. For more information about the project, please contact Professor Søren Kyllingsbæk, [email protected] or Associate Professor Thor Grünbaum, [email protected]. The larger project develops and tests a new theory of basic cognitive selection mechanisms by combining methods and perspectives from experimental psychology, cognitive neuroscience, mathematical modelling, and philosophy. The core idea is that selection in cognition may be understood as a biased competition between representations in a stochastic race (Grünbaum, Oren, & Kyllingsbæk, 2021). In a series of experiments, we have consistently shown that tasks-sets are competing biased by their importance and that this selection process is severely capacity limited. We will extend our new experimental procedures and mathematical models to the study of selection in planning and problem-solving. If our conjecture is true, higher-order cognitive processes like task selection, planning, and problem-solving depend on the same type of selection.

The postdoc will be part of a project entitled Selection in Cognition funded by the Carlsberg Foundation and headed by Prof Søren Kyllingsbæk and Assoc Prof Thor Grünbaum. Applicants are asked to situate and develop their research plan within the framework of the Selection in Cognition project. For more information about the philosophical aspects of the project, please contact Assoc Prof Thor Grünbaum ([email protected]). The philosophical project concerns the hypothesis that vague and ambiguous theorizing in cognitive neuroscience is a cause of the low replicability of experimental studies. More than half of the studies in psychology do not replicate. Researchers commonly blame poor methodological and statistical practices. Recently, a growing number of researchers have argued that the crisis is due to poor theories. The aim of the project is to use the analytical tools of philosophy of science to assess the claim that absence of proper theorizing is the root cause of low replicability and to understand the type of theory needed to alleviate the crisis.

The position covers the field of parasitology with a special emphasis on disease ecology, health and climate, and how hosts, vectors, parasites and other pathogens interact. The position aims to integrate modern methods in spatial modelling and experimental approaches within parasitology, to understand and predict how animal- and human parasitic diseases and vectors respond to climate- and other environmental changes. Through building of knowledge and capacity in this research field, the associate professor will contribute to new approaches for improved prediction modelling, monitoring and control of climatically sensitive diseases and vectors.

We invite highly qualified, thorough and motivated applicants to apply for the positions. The postdoc will be involved in the project listed below as well as participating in the daily duties of the Department. The project will focus on a project in biostatistics, specifically in two subprojects (Causal estimation and optimal treatment targeting with and without identification of the causal effect of interest). The project aims to develop methods and software that allow for the bounding and or targeting of optimal personalized treatment and the estimation of effects under such treatment decisions.  The Postdoc will work on three overarching topics and is encouraged and expected to drive the ideas and solutions within these topics, but also potentially other topics selected and driven by the postdoc:

Extrachromosomal DNA circles are known from tumors where they carry proto-oncogenes and can induce tumorigenesis (DOI: 10.1016/j.tig.2022.02.007). Our recent data reveal that circular DNA is also found in blood plasma as circular circulating tumor DNA (circular ctDNA), suggesting that this new type of ctDNA can be an efficient marker for cancer. We now aim to find patterns of the circular DNA in blood plasma and tumors from our thousands of samples that can serve as markers for cancer, relapse and prognosis of cancer. We will put emphasis on applying and developing cutting-edge bioinformatics methods for identification of patterns in circular DNA and novel structural circular DNA variants. The development of the methods for will include clustering and machine learning methods with output allowing for biological interpretations of the roles of circular DNA in cancer.

The position is funded by a Villum Young Investigator research grant and a Revive&Restore/Morris Animal Foundation grant to Assistant Professor Josefin Stiller. The postdoc will work on two projects. The first project involves a large-scale genomic dataset of hundreds of whole genomes of Syngnathiformes that our lab is generation, on which the postdoc will perform phylogenomic analyses to understand the evolutionary relationships and the sources of phylogenetic incongruence. These phylogenetic insights will be important for ongoing comparative genomics analyses on this dataset. Secondly, the postdoc will lead a conservation genomic project that aims to investigate connectivity, adaptive potential, and genetic diversity of leafy and common seadragons using whole genome resequencing for ca. 200 individuals. The goal is to develop a conservation genomic assessment of the population genetic health of these two species to inform conservation stakeholders in Australia.

Introduction
The position is part of an externally funded project Purchase Power – SPP through private law enforcement (PURPLE) PurpLE aims to analyse EU and national public procurement laws from various national contract law perspectives. That is since the goals of public procurement are embedded in the public contracts, which are often regulated by contract law. Consequently, the latter implements public procurement aims and therefore affects if and how e.g. sustainable procurement goals are achieved. The project is hosted by CEPRI – Centre for Private Governance, which is a collaborative research centre. The overall aim of the centre is to conduct research on the legal implications of private governance, i.e. private actors taking over (traditionally) public tasks and functions. CEPRI provides a stimulating, diverse and inclusive work environment with approx. 25 researchers with various legal expertise and background, both international and Danish.

We are looking for a highly motivated and dynamic researcher for a 21-month position, who holds a PhD and has a background in neuroscience or neurophysiology and single cell/spatial transcriptomics or bioinformatics to commence on the 1st September 2023 or as close to this date as possible. The position entails molecular profiling of the entorhinal cortex in the murine and porcine brain using smart-seq, bioinformatic analyses of smart-seq datasets and comparing this technology to data obtained from Merfish and multi-electrode arrays. The position also involves a short stay at Harvard University, US with a collaborating group to perform Merfish.

 

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral position on the regulatory and ethical aspects of AI (with focus on privacy and data protection (GDPR))

Deadline : 30-06-2023

View details & Apply

 

Applicants are expected to have an excellent knowledge and strong research background in modern developments in gravity, field theory, holography and string theory. It is an advantage if the applicant has interest/experience in topics related to Carrollian physics, black holes and non-Lorentzian geometries. The postdoc’s duties will include research within the area described above as well as some contributions to teaching. The post may also include performance of other duties.

We are looking for a highly motivated and dynamic postdoc for a 3-year position, that will join an international team focusing on signalling. The postdoc is expected to start 1 November 2023 or after agreement. The postdoc will be heading a project to develop novel methods to functionally interrogate phosphorylation sites in cells using pooled lentiviral base editing screens.

The successful candidate will join a research group that utilizes genome-wide technologies, including genomic and epigenomic profiling, NGS and single-cell genomics as well as approaches in 3D cell culturing and xenograft transplantations. We use genomics-driven strategies to characterize and classify patient subgroups to identify oncogenic drivers and addiction networks with the aim of improving diagnostics and treatment. We unite research directly on patient samples and clinical data with basic molecular in vitro and in vivo models.

Extracellular vesicles are secreted by most cells types and carry bioactive molecular content (e.g., proteins, lipids, and nucleic acids) to peripheral tissues that can be transferred through membrane fusion and be functional in this new location. The EV proteome drastically changes immediately after acute exercise. The candidate will work towards identifying the role of EVs in regulating peripheral tissue metabolism in response to exercise.

Your task will be to design and establish methods to determine the best formulation approach for model poorly soluble drugs. These will include solubility and supersaturation propensity of drugs in both polymer solutions and lipids. Based on this, formulations will be developed and characterized by in vitro models, e.g. in vitro digestion and dissolution/permeation models. Finally, the success of the formulation strategy will be evaluated by pharmaco-kinetic studies in rats.

The postdoc will be working within an on-going collaborative research centre, titled Centre for Geo-enhancing Biological Productivity with Glacial Rock Flour, funded by the Novo Nordic Foundation. The centre aims to assess the potential to use Greenlandic glacial rock flour (GRF) to enhance both agricultural and marine productivity while simultaneously sequestering CO2 through enhanced weathering. The centre is led by Minik Rosing at the Globe Institute at University of Copenhagen, but includes partners from Australia, Ghana, Greenland and other institutes in Denmark, including PLEN, where the current position is placed.

The postdoc’s duties will include research on spatial and temporal soil biogeochemical data. Tasks will include applying novel approaches and high-resolution imaging techniques (e.g. optodes, zymography, 2D-DGT) to quantify and map gradients of soil biogeochemical parameters across the rhizosphere. These techniques will elucidate how the abundance and concentration of key chemical species varies across the soil pore to root matrix and how this may influence microbial activity and functions in bulk vs. rhizosphere and rhizoplane soil.

The Research Assistant will collaborate with Associate Professor Mathias Wullum Nielsen and Postdoc Claudia Acciai on a project focusing on national- and institution-related status dynamics in science, financed by the Carlsberg Foundation.

The job concerns the area of public health dentistry, where we approach oral health from a social and societal point of view. We expect a general knowledge related to oral health care and odontology with emphasis on interdisciplinary collaborations. As an associate professor, your research is expected to have impact on both patients and on society. You will undertake research projects with relevance for society and stakeholders including patients, practitioners, and decision makers. Furthermore, you are expected to develop and conduct teaching primarily within community dentistry as well as health informatics, and statistics using evidence-based medicine as the framework. Furthermore, course management will be required in one or more subjects within the pre-graduate curriculum of odontology.

We seek a data scientist to derive insights from host-microbiome multi-omics data in multiple consortium projects studying human and animal health, including GALAXY/MicrobLiver studying liver fibrosis (https://www.sdu.dk/en/forskning/galaxy), MICROB-PREDICT studying late-stage liver cirrhosis (https://microb-predict.eu/) and PIG-PARADIGM to combat antimicrobial resistance (AMR) in pig production (http://pig-paradigm.net). We strive to integrate and interpret these data derived from microbiome (e.g., metagenomics, metatranscriptomics, viral metagenomics, metabolomics, metaproteomics) and host (e.g., genetics, proteomics, circulating metabolomics) in collaboration with international data science partners (e.g., EMBL-Heidelberg; University of California, Davis) and other project partners. The current state-of-the-art for multi-omics integration and interpretation leaves much to be desired. Fortunately, our ongoing work leveraging a deep learning approach (autoencoders) integrates multi-omics data and generates biologically relevant insights using a biologically informed machine learning framework. Our ambition is to strengthen this research direction using expertise in data science and machine learning.

We seek a bioinformatician to develop computational workflows to analyse largescale microbiome multi-omics data in multiple consortium projects studying human and animal health, including GALAXY/MicrobLiver studying liver fibrosis (https://www.sdu.dk/en/forskning/galaxy), MICROB-PREDICT studying late-stage liver cirrhosis (https://microb-predict.eu/) and PIG-PARADIGM to combat antimicrobial resistance (AMR) in pig production (http://pig-paradigm.net). We strive to implement efficient and scalable workflows to analyze and integrate these data derived from metagenomics, metatranscriptomics, viral metagenomics, metabolomics, and metaproteomics in collaboration with international data science partners (e.g., EMBL-Heidelberg; University of California, Davis) and other project partners. We have recently published the MIntO package (https://github.com/arumugamlab/MIntO) that integrates bacterial metagenomic and metatranscriptomic data. Our ambition is to develop new workflows that expand MIntO’s features (e.g., novel analysis types) as well as datatypes (e.g., metabolomic data).

The growing obesity epidemic has escalated the progression of a series of non-communicable diseases, including type 2 diabetes and non-alcoholic steatohepatitis (NASH). While efficient pharmacotherapies have been developed for management of type 2 diabetes, there are no medications approved to treat NASH or for its predecessor non-alcoholic fatty liver disease (NAFLD). This project is based on an interdisciplinary collaborative approach between the Clemmensen Group and the Sakamoto Group and includes medicinal chemistry, in vitro/cellular pharmacology, metabolic signaling and preclinical pharmacology. We have developed first-generation liver-targeting pharmacological candidate molecules for safely targeting hepatic metabolic processes to improve liver health in context of fatty liver diseases (NAFLD and NASH). We have preliminary proof of principle in vitro and in vivo data and we are now eagerly looking to accelerate further preclinical testing in appropriate genetic and disease models relevant to liver and other metabolic diseases, including loss-of-function models to confirm target engagement in vivo. As such the project bridges from basic understanding of molecular mechanisms to translation and innovation. Your key tasks will be to design and perform in-depth in vivo pharmacology and metabolic/biochemical analysis of various strains/disease conditions of animals treated with the drug of our interest.

We are seeking a highly motivated researcher who will analyze and integrate a range of omics data (transcriptomics, epigenomics, metabolomics, proteomics) with comprehensive metabolic phenotyping from a range of clinical and preclinical models (e.g. cell, rodent, and human) to identify important targets in the regulation of circadian rhythms and metabolic health. Your responsibilities will include carrying out all major computational analyses of the project:  Analysing and interpreting high-throughput sequencing (RNA-seq, bisulfite sequencing, ChIP-seq) and mass spectrometry (metabolomics, proteomics) data obtained from metabolic tissues as well as previously published datasets. You will be working with a team of biologists/clinicians and bioinformaticians; therefore, you are expected to support the team with the experimental design and statistical interpretations of the experimental results

The main objectives of this post-doctoral project are to elucidate the interplay between energy sensing pathways (predominantly AMPK) and the circadian clock to regulate systemic metabolism. To understand the impact of AMPK on circadian biology, skeletal muscle-specific AMPKγ3 knockout and AMPKγ3 transgenic mice, and respective wild-type mice, will be studied. Mice will be studied across a 12h:12h light:dark cycle to characterize the role of AMPK in regulating circadian metabolism. The role of AMPK in regulating mitochondrial rhythmicity will be investigated by crossing mito-QC mice with AMPKγ3 knockout and transgenic mice, and studying mitochondrial respiration, mitophagy, and mitochondrial content across the circadian cycle. Finally, we will determine the role of skeletal muscle AMPK in the circadian response to energetic stressors via timed exercise and fasting in AMPKγ3 knockout and transgenic mice.

A major challenge in academia and in the pharmaceutical industry is to transform early-stage projects into valuable assets through effective target validation studies. As a postdoctoral researcher, you will be the expert in validating the physiological role and pharmacological potential of GPR39 in prevention and treatment of metabolic disorders. To achieve this, you will utilize agonist leads developed in-house in ex vivo and in vivo target validation studies. The prototype agonist leads have already been scaled up in amounts suitable for long term chronic in vivo studies in rodents, enabling a series of unique target validations studies of increasing complexity. To ensure that your research has maximum impact, you will establish collaborations with other research groups at the Center, enabling you to take full advantage of the state-of-the-art technologies available, especially at the Rodent Metabolic Phenotyping Platform. Your primary responsibilities will involve characterizing the mechanism of action of the agonist leads and build a strong efficacy package, with the ultimate goal of validating the physiological role of GPR39 in regulating, type-2 diabetes, NAFLD and ALD.

This research project probes Medical Museion’s focus on the links between CBMR’s research and society-at-large. It uses two sites of enquiry: first in its experimental events, workshops, and installations that draw on what museums are good at (using their collections and other visual/material culture, their charged spaces for hosting events, as well as their curatorial expertise and experience of bringing together people and things), and second a series of ‘temporary displays’ currently being developed for a couple of Medical Museion’s modest rooms, which will have a strong focus on exploring dilemmas and encouraging broader public conversation.

The successful candidate should have a Ph.D. in computational biology, computational genomics, biostatistics, computer science, or a related quantitative field and be interested in developing and applying novel computational and statistical methods for analysing single-cell RNA sequence combination with publicly available and individual-level data to gain biological insights into cell-type specific processes that converge into diabetes and cardiovascular disease. The work will contribute to a collaborative international effort to accelerate discovery from genetic maps to biological mechanisms to physiology and clinical translation.

The Postdoc fellowship is aimed at early-career researchers with a basic science background or clinicians who aspire to a career in academic medicine. We are particularly interested in candidates who are familiar with integrative research approaches within the broad area of basic cardiometabolic research with an application toward human pathophysiology.

You will become part of the Section of Food Analytics and Biotechnology at Department of Food Science in a successful and growing research group, in which we offer you an attractive position, where you can develop your own research focus. We expect you to have a background in food science or analytical chemistry with strong interest in plant seed proteins for food and sustainable postharvest food production. You should be highly skilled in analytical approaches for plant seed protein extraction, and application of chemical or biochemical approaches for assessing the quality of protein in raw material as well as in processed products (e.g. in vitro protein digestibility and amino acid composition). Research experience in separation of plant seed proteins, analysis of anti-nutrients and quality of proteins from plant sources are needed requirements. Research experience with analytical tools for further characterization of plant seed proteins will be regarded as an additional advantage.

We are looking for a highly motivated and dynamic postdoc for a 2-year position to commence on 1 September 2023. You will work in Wennerberg group at the Biotech Research & Innovation Centre (BRIC) using advanced glioblastoma cell culture models to search for new precision medicine treatment strategies.

The postdoctoral position is part of a 5-year Starting Grant from the European Research Council (ERC) led by Kathrin Rousk. The main goal of the postdoctoral project is to model ecosystem nitrogen (N) input via moss-associated N2 fixation in boreal forests and tropical cloud forests, and to model the resource optimization of moss-associated N2 fixation. The ultimate goal is to constrain and parameterize a dynamic vegetation model (i.e. LPJ-GUESS).