41 Postdoctoral Fellowship at University of Cambridge, United Kingdom

Applications are invited for a Postdoctoral Research Associate position to help direct and conduct research in a team of scientists under the leadership of Prof Duncan Astle, alongside a wide team of collaborators across the University of Cambridge. The research work will support a Medical Research Council funded research programme aimed at understanding how the development of the human brain, and characterising the drivers of variability in that development. This role holder will use a range of methods, and a strong quantitative background is highly desirable for the role.

Research conducted in the lab sits at the intersection between developmental systems neuroscience, cognition, neuroinformatics and computational modelling. Anyone with experience in those areas is encouraged to apply. A hallmark of our work is the application of novel methodological approaches to large scale datasets, so experience with this would be a real advantage.

We invite applications for a Research Assistant/Associate position in the group of Prof. Bartomeu Monserrat at the University of Cambridge. We are looking for a motivated, independent, and talented scientist to join our group.

This is an open call in the general area of condensed matter and materials modelling. The successful candidate will work in one or several of the current areas of interest in the group, which include:

• Topological materials
• Exciton-phonon coupling
• Superconductivity
• Strongly correlated materials
• Machine learning

This is an exciting opportunity for an enthusiastic Astronomical Data Scientist to work within the Cambridge Astronomical Survey Unit (CASU) at the Institute of Astronomy (IoA) as part of CASU’s spectroscopic analysis system development team.

WEAVE, MOONS and 4MOST are major massively-multiplexed optical/NIR spectrographs currently under advanced stages of development, to be deployed on the 4.2-m William Herschel, ESO VLT and VISTA telescopes respectively. They will enable large, cutting-edge spectroscopic surveys to be undertaken across both hemispheres, observing millions of stars and galaxies during their initial multi-year survey periods. The CASU team has developed the spectroscopic pipelines for WEAVE and 4MOST and has responsibility for the final development, commissioning and operations of the data pipelines. CASU is developing the data flow system and housing the survey operations centre for MOONS.

Applications are invited for a postdoctoral chemist to work with Professor Sir Shankar Balasubramanian on the chemical biology of nucleic acids, funded by Cancer Research UK. The successful applicant will work on an interdisciplinary project to elucidate the function and biological mechanisms of four-stranded DNA G-quadruplexes and to investigate their potential as therapeutic targets and biomarkers of cancer. See DOI: 10.1016/j.trechm.2019.07.002, DOI: 110.1073/pnas.2320240121 and https://www.balasubramanian.co.uk for further information.

Applicants must have a background in chemical or molecular biology, with strong interest in DNA-related mechanisms. Experience in biochemistry, nucleic acid-protein interactions and transcriptional control would be highly desirable. We seek a highly-motivated individual with good communication skills and a capacity for innovation and creativity, who is able to work well as part of a multi-disciplinary team.

We are looking for a highly motivated, proactive and enthusiastic postdoc to work on a Wellcome Trust funded project within the Galliano laboratory the University of Cambridge. Our research focuses on investigating how brain cells change in response to altered sensory inputs, and how such changes in brain cells underpin adaptation, learning and memory at the behavioural level. We use mice as model systems, and we probe the brain networks that encode their sense of smell. We are an inclusive, diverse and welcoming group, invested in open-science and outreach, and committed to mentoring and supporting the career development of all members.

We are seeking to appoint a postdoctoral researcher to better understand the role of cellular senescence as part of the lung tumour microenvironment and the interplay with the immune system. The postdoc will be based in the laboratory of Dr Daniel Munoz-Espin, Group Leader in the Department of Oncology (Early Cancer Institute) at University of Cambridge and co-Director of the Thoracic Cancer Programme. This post funded by a Cancer Research UK (CRUK) Programme Foundation Award is available from September 2024.

Dr Munoz-Espin’s research programme aims to understand the mechanisms and processes that contribute to lung cancer initiation and progression, and how to use this knowledge for the development of more efficient therapeutic strategies in precision medicine. We are looking for highly motivated postdocs to explore the impact of a senescent microenvironment and the modulation of the immune system in lung carcinogenesis. Additionally, we will investigate dynamic changes of this process during natural ageing. Candidates must have a PhD in the biological/biomedical sciences, and significant experience working in immunology, cancer biology, and/or cell senescence with animal models and/or clinical samples. Experience in immune system profiles (flow cytometry/CyTOF analyses) is essential. Skills in spatial multiplexed imaging, multiomics analyses, generation of organoids and/or computational skills will be evaluated positively. International training and/or interconnections with the research industry are desirable. Original publications in peer reviewed journal/s will be positively considered.

The Bulstrode Lab studies the biology of neural stem cells in development, cancer and neurodegeneration. We are also developing new technology for targeted delivery of treatments to patients. Recent grant awards from Parkinson’s UK and Brain Research UK will each fund a Postdoctoral Research Associate to join the group and work respectively on:

(1) ‘Developing an Adaptable Dopamine Cell Therapy for Parkinson’s Using the HIF Pathway’

(2) ‘Gene and mRNA therapy approaches to Tumour Associated Macrophages in Glioblastoma’.

The successful candidates will have a strong basic science research track record at doctoral level. Experience in some or all of mammalian cell culture, routine molecular biology workflows, imaging, cloning, and next generation sequencing analysis is highly desirable.

A position exists, for a Research Assistant/Associate in the Department of Engineering, to work on BuildZero.

The post holder will be located in Central Cambridge, Cambridgeshire, UK.

The key responsibilities and duties are:

• Developing a complete characterisation of the UK building stock
• Developing dynamic stock and flow tools
• Liaising and networking with BuildZero research team and industrial partners
• Planning and organising research and reporting

Applications are invited for a Research Associate/Fellow in Computational Psychiatry to join the Mental Health Neuroscience lab led by Dr Camilla Nord at the MRC Cognition and Brain Sciences Unit, University of Cambridge.

The post holder will form part of our interdisciplinary lab of cognitive neuroscientists at the MRC CBU developing neuroscientific methods to better understand and treat neuropsychiatric disorders. The current major focus of the lab is the intersection of computational psychiatry and brain-body interactions.

The post holder will lead on development of new computational psychiatry projects in the lab, working closely with the PI to design new studies, coordinate with clinical and research collaborators (when relevant) to collect data, analyse data from existing and future projects, and write papers. The post holder’s work will explore the relationship between mental and physical health using formal computational modelling of cognitive tasks, with a particular emphasis on causal probes including psychopharmacology.

The Department of Architecture is seeking a Post-Doctoral Research Associate to join our Centre for Natural Material Innovation (CNMI). The role-holder will work on CNMI’s Horizon Europe funded research project, ‘UPWEARS: Sustainable solutions for upgraded smart wearables and equipment in sport’.

This is a full-time, fixed-term role, based in Cambridge, with funding for 39 months. The role-holder will work in close collaboration with colleagues at INRAE (French National Research Institute for Agriculture, Food and Environment, Coordinator of UPWEARS), and have the opportunity for short-term research visits to INRAE (Nantes).

The textile industry is a major contributor to environmental pollution due to issues like dyes and microplastics, water and energy consumption, and end-of-life waste generation. With 15 international partners, UPWEARS aims to develop a new generation of recyclable biobased e-textiles for smart, multi-functional wearables in sport. The role-holder will contribute to a primary goal of UPWEARS: to use concepts inspired by nature to achieve upgraded performance of technical textiles such as shock absorbance, breathability, and bioluminescence.

The post-doctoral research assistant / associate will join the Kromdijk lab at the Department of Plant Sciences to work on chilling tolerance in maize. Maize is a global food, feedstock and bioenergy crop with a world-wide production volume of 1.09 billion metric tons. Maize was domesticated by ancient farmers in Mexico approximately 9000 years ago and is one of the most susceptible crops to chilling-induced photoinhibition amongst those grown in temperate regions. As a result, maize yields at higher latitudes are limited by a relatively short growing season and maize is sensitive to yield losses due to early and late season cold snaps and poor early season establishment of sufficient leaf area to efficiently capture light and compete with weeds.

The post-doctoral research assistant / associate will join the Kromdijk lab at the Department of Plant Sciences and be embedded in a larger research team seeking to deploy new thermal detection technology to address a range of global change issues.

The postdoc’s project aims to perform lab-based experiments on the effect of elevated temperature on selected species from a peatland ecosystem (Scottish Highlands, Cairngorms) using a range of optical sensing techniques (thermal, chlorophyll fluorescence and reflectance), which are suitable for upscaling. Ultimately, these controlled experiments aim to enhance our ability to predict peatland responses to global warming.

The overall team is interdisciplinary, comprising researchers in the Plant Sciences, Architecture and Astronomy Departments as well as the industrial partner Super Sharp Space Systems Ltd, who are leading the overall project.

The Bartlett lab studies the developmental and evolutionary processes underpinning plant diversity. We work to identify the genes that regulate plant development, describe the evolutionary histories of these genes, and connect molecular evolution to the evolution of plant form. Traits we focus on include the evolution of sex determination (Gallagher et al, 2023; Klein et al, 2022, and Subramaniam and Bartlett, 2024), and the evolution of floral organ elaborations called awns ( Schrager-Lavelle et al, 2017; Patterson et al, 2023, 2024). Floral sexuality and awns can be important in crop productivity. Thus, our work dissecting the mechanisms underpinning morphological diversification can have translational applications.

You will explore the molecular development and evolution of sex determination, or the development and evolution of awns. The precise direction of the project will depend on your expertise and interests. Whichever direction the project takes, you will explore morphological and molecular evolution using a range of techniques, including molecular biology, comparative anatomy and morphology, evolutionary genomics, phylogenetic comparative methods, quantitative phenotyping, and microscopy. You will have expertise in one or more of the experimental systems or techniques we use, with a willingness to gain expertise or collaborate in other areas. Foundations in molecular biology and plant developmental biology are required. We particularly welcome candidates with expertise in grass transformation. Proficiency in molecular cloning, genomics and bioinformatics, comparative anatomy and morphology, phylogenetic comparative methods, molecular evolution, or image analysis would also be valuable.

A position exists for a Research Associate in Nanomechanics of Organic Semiconductors. The aim of the role is to understand the mechanical properties of organic semiconductors, characterised jointly using microelectronic devices and an atomic force microscope (AFM). Organic semiconductor devices are known for their deployment in large area flexible electronics. Their mechanical properties on the scale of a few molecules are only starting to be probed. Our team demonstrated high-resolution, nanometre-scale, mechanical measurements on organic semiconductors [I. Dobryden, V. V. Korolkov … D. Venkateshvaran, Nature Communications 13, 3076 (2022)] and have since pushed the limits to measurements on the scale of few molecules. In the work proposed for an incoming Research Associate, we intend to bring these measurement skills together with devices to demonstrate nanomechanical property tunability in organic semiconductors using electric and thermal fields. These experiments will evolve a deeper understanding of how mechanical properties, electronic properties, and thermal properties, in organic semiconductors are interlinked on the nanoscale.

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Research Assistant or Research Associate (In vivo biology)

Deadline : 25 August 2024

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The Maori lab (https://www.bioc.cam.ac.uk/research/maori), based in the Department of Biochemistry at Cambridge University, is inviting applications for a Research Assistant/Research Associate. The position holder will join our research programme, which centres around RNA transmission between organisms.

RNA flow between organisms has been documented within and among different kingdoms of life. To date, known functions of such transmissible RNA have been limited to host-parasite interactions where the RNA negatively affects the recipient organism. Nevertheless, the question of why any organism would uptake regulatory RNA from the environment has remained largely unanswered.

Honeybees are eusocial insects, living in a colony that is often described as a superorganism. RNA mobility between cells of an organism has been shown in animals and plants. We recently discovered that RNA spreads further in honeybees and is horizontally transferred between individuals and across generations (Maori et al., Mol Cell, 2019; Maori et al., Cell Reports, 20219). Ongoing work in the lab has revealed that RNA originating from a gut-restricted bacterium is taken up and spread systemically within the bee host and has the capacity to target honeybee pathogens. Yet, the extent of RNA transmission between honeybees and their surrounding micro-organisms is poorly understood.

The ALBORADA Drug Discovery Institute (ADDI), part of the University of Cambridge Institute for Medical Research (CIMR) (http://cambridge-ddi.alzheimersresearchuk.org/), is seeking a Research Associate with a strong background in biochemistry and/or biophysics to join its established team. The ADDI is part of a network of world-class Drug Discovery Institutes, funded by Alzheimer’s Research UK, forming the Alzheimer’s Research UK Drug Discovery Alliance. The work of the ADDI at Cambridge is aimed at validating new drug targets and identifying potential new drugs for the treatment of Alzheimer’s disease as well as other types of neurodegeneration.

The ideal candidate will have demonstrable experience in assay development and the mechanistic validation of biological targets. Using biochemical and/or biophysical techniques, you will be responsible for designing and conducting studies to validate the link between putative targets and relevant disease mechanisms, as well as to characterise and assess compounds emerging from our drug discovery pipeline. You will collaborate closely with colleagues in the cell molecular biology and the in vivo teams, and work alongside medicinal and computational chemists to progress projects from target validation through to in vivo proof-of-concept models.

Applications are invited for a 17 months’ post-doctoral position starting 1st Oct 2024. The work will be carried out in the Victor Philip Dahdaleh Heart & Lung Research Institute (VPD-HLRI). This new institute and building provide an exceptional and stimulating environment that promotes collaborative and interdisciplinary research, with state-of-the-art facilities, and is housed on the Cambridge Biomedical Campus adjacent to the Papworth Hospital and AstraZeneca Discovery Centre.

The project is to perform in vivo phenotypic characterization accompanied by cell biological mechanistic studies to delineate how dysregulated endothelial bone morphogenetic protein (BMP) signalling causes Hereditary Haemorrhagic Telangiectasia (HHT). HHT is primarily caused by mutations in ACVRL1 or ENG genes, encoding the receptor and co-receptor of endothelial BMP ligands. The goal of the project is to develop novel therapeutics for treating HHT.

The group has a broad research program and explores problems at the frontier of organic and hybrid semiconductors, 2D and quantum materials. A key tool for these studies has been the development of ultrafast transient optical microscopy (TAM), which now allows us to track the transport of photoexcitations in three-dimensions with sub-10fs temporal resolution and sub-5nm spatial precision. This has opened a new frontier for the study of the spatiotemporal dynamics of photoexcitations on time and length scales dominated by quantum effects rather semi-classical behaviour [1-6].

We are looking for a highly motivated and enthusiastic candidate with a strong background in ultrafast spectroscopy/microscopy. You will have a PhD in Physics, Chemistry or a related area, and should have demonstrated excellency in multi-disciplinary research projects. An interest in designing and constructing novel ultrafast experiments and a strong background in non-linear optics, the photophysics of semiconductor and solid-state systems will be required. Experience with ultra-short pulse generation, time-resolved microscopy, pulse shaping techniques, high-speed data acquisition and optical holography/tomography would be a plus. You will be expected to participate actively in collaborations with other post-doctoral researchers and PhD students.

Applications are invited for a Medical Research Council-funded Research Associate post in the field of platelet activation and arterial thrombosis. The successful applicant will join Dr Matthew Harper’s research group in the Department of Pharmacology, University of Cambridge.

Dr Harper’s research group focuses on platelet activation during thrombosis. A key aim of the current project is to understand how non-occlusive arterial thrombi affect circulating platelets and downstream thrombotic events. Candidates should have a PhD in a relevant biological subject, or be preparing to submit their PhD soon, and will ideally have a strong background in cardiovascular research. Experience with platelets or microfluidics would be advantageous. An ideal candidate would also have experience of in vitro models of thrombosis, platelet flow cytometry, microscopy or whole blood assays, but we are happy to consider applications from enthusiastic researchers who would bring new skills and perspectives to the lab.

The key responsibilities and duties are:

1. Research and scholarship: develop research objectives and proposals for own or joint research; conduct individual and collaborative research projects; write up research work for presentation and publication; assist in the preparation of proposals and applications to external bodies, e.g. for funding and contractual purposes.
2. Teaching and learning support: may assist in the supervision of student projects; provide limited supervision/instruction to classes.
3. Liaison and networking: liaise with colleagues and students; build internal and external contacts and participate in networks for the exchange of information and to form relationships for future collaboration.
4. Planning and organising: plan the use of research resources, laboratories and workshops as appropriate.

A position exists for a Research Associate in the Department of Engineering’s Whittle Laboratory on the West Cambridge site (Cambridge, UK), to work on the Aviation Impact Accelerator project.

Climate neutral aviation is possible. However, there is no silver bullet and to achieve it a whole system approach is required considering technology, scaleup, infrastructure, investment, and policy. The Aviation Impact Accelerator is an international group of academics and practitioners drawing on a broad range of expertise assembled by the University of Cambridge, to develop an interactive, evidence-based tool to engage decision makers and the wider public in a discussion on the pathways to net zero flight.

Key responsibilities and duties include: investigating technologies for climate neutral aviation; contributing to academic and popular outputs including articles and papers; developing system models of aviation; working closely with AIA team and external partners; building internal and external contacts and participating in networks for the exchange of information and future collaboration; planning and managing your own research activity in collaboration with others; contributing to the planning of joint research led by the principal investigator.

A postdoctoral position is available in the Henderson group to investigate centromere structure, function and evolution using the model plant Arabidopsis thaliana, funded by the ERC and UKRI. The post is available for three years in the first instance, with the possibility of further extension.

The successful candidate will lead an ambitious experimental genetic program to dissect centromere structure and function, using genetic and epigenetic modification in Arabidopsis. The project will involve combining classical genetics with Oxford Nanopore long-read DNA sequencing, and CRISPR-mediated genome and epigenome engineering. The objective is to understand fundamental aspects of centromere identity, with cross-cutting relevance across eukaryotes. Knowledge of centromere identity will also find translation in building plant synthetic chromosomes.

A postdoctoral position is available in the Henderson group to investigate centromere structure, function and evolution using the model plant Arabidopsis thaliana, funded by the ERC and UKRI. The post is available for three years in the first instance, with the possibility of extension.

The successful candidate will lead an ambitious bioinformatics program to dissect centromere structure and function, using both genetic and epigenetic data in Arabidopsis. The project will involve analysing data derived from classical genetic experiments, as well as Oxford Nanopore long-read DNA sequencing, and the results of CRISPR-mediated genome and epigenome engineering. The objective is to understand fundamental aspects of centromere identity, with cross-cutting relevance across eukaryotes. Knowledge of centromere identity will also find translation in building plant synthetic chromosomes.

We are pleased to offer a 10-month post-doctoral research associate position to work on the final stages of an ambitious three-site cross-cultural study of children’s school readiness safely.Given the complex nature of the data from this study, you must have a strong track record in applying sophisticated statistical analyses (e.g., structural equation modelling, testing for measurement invariance), and in drawing culturally appropriate interpretations of the results.
More than half of the raw data involves videos or transcripts from Chinese speaking families and so you must also be fluent in Mandarin and/or Cantonese (as well as having excellent spoken and written English).

Applications are invited for two full-time Research Associate positions. The positions are fixed term for 2 years, with a start date of 01 October 2024, or as soon as possible thereafter. The latest possible start date is 01 January 2025. The successful applicants will work on an ERC-funded project led by Dr Catherine A. Bradley at the Faculty of Music.

The project offers the opportunity to conduct research into ritual contexts for and musical and poetic responses to the exclamation Benedicamus Domino (‘Let us Bless the Lord’) in the period c.1000 — 1500. Candidates should propose a research project within this broader framework that relates to their own research interests and expertise to pursue over the course of the position.

A position is open for a Postdoctoral Research Associate/Assistant as part of an ERC awarded project funded by UKIR at the University of Cambridge in the group Catalysis and Process Integration group led Dr Laura Torrente (www.capi.ceb.cam.ac.uk).

The successful candidate will have a strong background in the synthesis and characterisation of heterogeneous catalysts and/or expertise in chemical reaction engineering, including a PhD in a relevant area. Experience in inorganic chemistry, nitrogen activation and chemical looping would be advantageous.

The aim of the project is the development of catalysts for the synthesis of green ammonia with a focus on the mechanisms of nitrogen activation and the use of readily available materials. The research will involve the investigation of novel ammonia synthesis routes, including chemical looping systems.

A position is open for a Postdoctoral Research Assistant/Associate as part of an ERC awarded project funded by UKIR at the University of Cambridge in the group Catalysis and Process Integration group led Dr Laura Torrente (www.capi.ceb.cam.ac.uk).

The successful candidate will have a strong background in sorption processes (i.e. absorption or adsorption), kinetic studies and characterization of materials, including a PhD in a relevant area. Knowledge of process design as well as the design, commissioning and use of flow systems will be advantageous.

The overall aim of the project is the development of novel green ammonia processes powered by renewable energy and able to cope with its intermittency nature. The position will focus on the study of absorption for the separation of ammonia at relatively low partial pressures. The research will focus on the mechanism and kinetics of ammonia on metal halides as well as their decomposition.

We are seeking an enthusiastic and motivated postdoctoral research associate with training and experience evaluating and delivering health behaviour change interventions and an interest in the psychology of obesity and weight management. You will take a lead role in a 5-year multi-disciplinary research programme led by Dr Amy Ahern and funded by an NIHR Programme Grant for Applied Research. This research programme will evaluate an acceptance-based guided self-help intervention to support weight loss maintenance. It builds on a successful feasibility study of the Supporting Weight Management (SWiM) intervention (DOI: 10.2196/31801) and will further refine, adapt and evaluate this intervention to provide evidence needed for implementation within the NHS.

Energy materials such as lithium ion batteries and fuel cells are prone to degradation by a range of failure mechanisms including swell-induced fatigue and micro-cracking. The apparent toughness may be a function of chemical composition, and the driving force for failure may have an electrical component in addition to mechanical component. Topology has a major effect both on performance and on the failure mechanisms.

There is a research opening for a Research Associate at the post-doctoral level (or a researcher who is soon to receive their PhD), with a working experience of solid mechanics and possibly with previous research on electrochemical technology. The job is to develop a coupled mechanical and electrochemical model for device performance and degradation.

The key responsibilities and duties are to conduct numerical research into the mechanics of batteries. The role holder is also expected take part in collaborative work, and contribute to seminars, and to take part in the research group’s activities, publish in the open literature and liaise with the sponsors.

The Applied Social Science Group within the Primary Care Unit are seeking to appoint an enthusiastic and motivated postdoctoral research associate to a project that explores the assessment of attachment and caregiving. The project will involve meta-analytic studies informed by attachment theory and research, seeking to learn more about assessing the needs of children and families.

The study is part of an international programme of research and engagement, supported by a consortium of over 200 researchers and practitioners from 31 countries. There will be ample opportunity for the post holder to collaborate and build their networks with international research leaders. We are looking for someone capable of working responsively and collaboratively, and with a desire to influence practice with children and families through research.

The successful candidate will join a friendly and supportive team, led by Professor Robbie Duschinsky. This team includes clinicians from various professions (e.g. clinical psychology, general practice, social work) and researchers from across disciplines (e.g. primary care research, epidemiology, sociology, psychology).

We are seeking a research associate or senior research associate who enjoys analysing data and solving statistical problems to join us for two years in the first instance. We have a range of programmes of research that you could contribute to, depending on your interests and skills, including a) longitudinal data analyses of pre-existing data (e.g., dSEM or causal approaches), b) computational modelling of behavioural data (e.g., reinforcement learning) and/or c) analyses of objective social media data (e.g., TikTok videos) through use of LLMs and other methodologies

This role will provide you with the freedom to develop new and creative ideas, methodologies, and/or approaches to challenging and societally important questions. You will be supported in finding a research area that interests you, and encouraged to develop a research programme of your own.

The Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments (https://www.stemcells.cam.ac.uk/).

The laboratory of Dr Mekayla Storer (https://www.stemcells.cam.ac.uk/people/pi/dr-mekayla-storer) uses multidisciplinary approaches to understand why the distal portion of the digit tip is the only part of the limb that can regenerate in mammals. The key step in this process is the formation of a blastema, a transiently proliferating mass of cells that the regenerates the different cell types of the digit to replicate the original structure. Therefore the broad goal of our research is to understand which cells and molecular pathways are necessary for this process. A portion of our present research builds on our previous work (Storer et al., Dev. Cell 2020) that used high-throughput single-cell mRNA sequencing and Cre-recombinase based lineage tracing to define the transcriptional identity of the mesenchymal cells comprising the blastema and the major transitions during mammalian digit tip regeneration. We are looking for a dedicated post-doctoral researcher to determine which of these factors present during digit tip amputation are necessary for successful regeneration and the mechanisms that underly this process. The post holder will use high-resolution imaging analysis, single cell transcriptomics/multi-omics approaches, in vitro culture with CRISPR-mediated gene regulation and in vivo transplantation assays.

You will work together with a team of students and research collaborators on the development of formally verified compiler infrastructure. In particular, our objective is to build technology that brings formally verified compilation into the day-to-day use of the LLVM/MLIR compiler ecosystem. In this context, we use and contribute to the Lean4 proof assistant where we build foundational technology, e.g., a powerful BitVector library, technology for coindictive proofs, an embedding of MLIR’s SSA data structures into lean, or a model of instruction-set level semantics. While we have a clear objective, the path towards this objective is very flexible. We may investigate automation via synthesis-guided superoptimization, improvements to interactive-theorem-prover-based verification, or follow some of your ideas. All our work is developed in close collaboration with the open-source community. Hence, we appreciate interest or even experience in large-scale open-source software development.

The successful applicant at the Research Associate level will possess a PhD in computer science or equivalent experience in compiler design and/or interactive theorem proving, and a track record of relevant scientific publications, whereas at the Research Assistant level must hold Masters results in Computer Science or equivalent experience. Excellent spoken and written English is essential for this role. We particularly encourage applicants who are enthusiastic about our project, even if their background and expertise are only tangentially related to this position.

A BBSRC-funded Postdoctoral Associate position is available in the Davies lab to study damage signalling in Arabidopsis triggered by root cyst nematodes. The successful candidate will explore the role of extracellular purines and calcium channels in this pathway, in collaboration with Prof. Sebastian Eves van den Akke (Crops Science Centre, Cambridge) and Prof. Taufiq Rahman (Department of Pharmacology, Cambridge). A combination of protein-protein interactions, calcium imaging, electrophysiology (including heterologous expression systems) and quantitative phenotyping can be deployed. The successful candidate will also be involved in preparing publications, presenting at conferences and supervising students.

Applicants must have or be close to obtaining a PhD in Plant Biology, Molecular Biology, Cell Signalling or a relevant field. Where a PhD has yet to be awarded the appointment will initially be at Research Assistant level (Grade 5) and amended to Research Associate (Grade 7) upon the award of your PhD.

Applications are invited for two 12-month Post-Doctoral Research Associate positions in the Department of Materials Science and Metallurgy at the University of Cambridge.

These roles will use advanced characterisation techniques to make critical assessments of the residual stresses present in aerospace alloys. One post will focus on solid state titanium welds, and the other will explore additively manufactured superalloy structures.

The posts will be based at the Rolls-Royce UTC and will be supervised between Prof. NG Jones, Prof. HJ Stone and Dr DM Collins.

Both posts will aim to provide a more complete understanding of the stress states that exist following solid-state welding (in Ti-6Al-4V) or additive manufacturing (in Ni-base superalloys) and how the material relaxes during subsequent thermal treatments.

The work will involve thorough microstructural characterisation and in situ experiments at national radiation facilities. The outcomes will not only be critical to our industrial partners but will be used by other collaborators to help develop more accurate process models. As such, these projects will involve regular meetings with industrial and academic specialists and, therefore, will require the production and delivery of high-quality oral presentations.

Applications are invited for a Research Associate to join the Prorok Laboratory in the Department of Computer Science and Technology, at the University of Cambridge, UK.

The Prorok Laboratory has a variety of robotic platforms (aerial and ground), and boasts expertise in controlling and deploying them in practice, as well as in designing coordination strategies. Our recent work on ML-based co-optimization demonstrates some of our key research directions relevant for this position.

The role holder will work together with a team of students and research collaborators on the development of learning-based discovery of robot task/environment designs that are conducive to successful completion of the problem at hand. Particular focus will be on multi-robot and multi-agent problems (e.g., navigation, cooperative transport, team-based agent games). There will also be opportunities to contribute to international collaborative projects with other universities as well as industry.

The Sawarkar lab at the MRC Toxicology Unit is looking to appoint a Research Associate (Postdoctoral Fellow) to contribute to its programme on Epigenetics, tRNA transcription and Neurodegeneration. The project will use state-of-the-art genomic technologies to identify epigenetic determinants that lead to protein misfolding in neurons.

Using single-cell technologies for in vivo mouse models as well as embryonic stem cell differentiation models of neurodegeneration, the project will identify mechanisms leading to age-associated protein misfolding in neurons. The focus of the work will be on the role of tRNAs in neurodegeneration and protein misfolding.