44 Postdoctoral Fellowship at University of Cambridge, United Kingdom

Applications are invited for a Research Assistant/Research Associate position in the group of Dr Alexander Jones at the Sainsbury Laboratory, Cambridge University.

The cellular dynamics of the plant hormones underpin all aspects of plant development and environmental responses. The Jones group at SLCU has recently engineered a series of high affinity FRET biosensors to track such dynamics for gibberellin, abscisic acid, auxin and salicylic acid in high resolution.

This post will involve targeted deployment of these FRET biosensors to illuminate previously undetectable cellular and subcellular hormone patterns in vivo. The project’s eventual aim will be aimed at gaining a mechanistic understanding of how and why hormone accumulations or depletions are modulated in space and time. The Jones group combines imaging of FRET biosensors with high-resolution genetic and biochemical perturbations to allow us to link signal integration upstream and program activation downstream of phytohormone cellular dynamics. We also collaborate with mathematicians to build multi-scale understanding of these complex and important signaling pathways.

The Cancer Research UK Cambridge Institute (CRUK CI) is a department of the University of Cambridge and has the specific goal to harness the scientific strengths of Cambridge to solve problems encountered with the treatment, diagnosis and prevention of cancer.

The Histopathology/ISH Core Facility offers a variety of routine and specialised histological techniques, including immunohistochemistry (IHC), in situ hybridisation (ISH), laser capture microdissection, automatic slide digitisation and image analysis to CRUK CI scientists.

We are now looking to recruit a highly motivated Research Assistant to join our team of ten and contribute to the achievements of our Core Facility. This is a general histopathology role which will include routine histopathological processing of paraffin and frozen samples, sectioning of these blocks through to routine H&E and special staining. In addition, the role holder will be expected to carry out routine IHC and scanning on a weekly rotational basis.

We are seeking an enthusiastic and highly motivated part-time research assistant to join our group, led by Professor Michael Nicholson, to work on the transformation and modification of kidneys for transplantation. Supervised by Dr Sarah Hosgood and funded by Kidney Research UK, the post will be based in the University of Cambridge Department of Surgery at Addenbrooke’s Hospital on the Cambridge Biomedical Campus (http://cambridge-biomedical.com).

In kidney transplantation, blood group compatibility is a major barrier to donor – recipient matching. Patients with more restrictive blood types like type O or B often wait twice as long for a kidney compared to patients with blood group A. Longer waiting times are associated with poorer outcome and a higher chance of patient death. To overcome this barrier, a major research theme of our group is the use of novel machine perfusion technology for the enzymatic conversion of blood group A and B kidneys to O-type.

We are seeking a highly motivated Research Assistant/Associate to join our team in the Department of Public Health and Primary Care on a new Cancer Research UK funded research programme focused on how to optimise implementation of breast cancer risk assessment into the NHS for women under age 50. The successful candidate will be encouraged to contribute to all components of the programme but will be expected to i) contribute to qualitative work with healthcare professionals and policy makers to identify key points in current pathways that would be impacted by the introduction of different approaches to the implementation of a proactive risk-assessment process; ii) support qualitative work with members of the public to co-design potential strategies for implementing proactive breast cancer risk assessment within current clinical care; iii) lead on the set up and data collection for an online survey with members of the public; and iv) lead on the design, data collection and analysis of a pilot study and subsequent cluster-randomised trial of proactive risk assessment within primary care.

The postholder will work within a programme focused on understanding mitochondrial dynamics and membrane contact sites as key regulators of cell fate decisions. Mitochondria form a dynamic and interconnected network that is constantly remodelled by cycles of membrane fission and fusion. These dynamic transitions are essential not only for proper mitochondrial function but also for responding to cellular needs and adapt to the metabolic state of the cell. To execute cellular functions, mitochondria establish membrane contact sites with other organelles, including the endoplasmic reticulum, peroxisomes, trans-Golgi network vesicles and lysosomes. These membrane contact sites are hotspots for metabolites flux and tightly regulate mitochondrial shape and architecture. While defects in mitochondrial morphology or contact sites have been associated with human diseases, the molecular mechanisms linking mitochondrial membrane remodelling to cell fate decisions are not fully understood.

The goal of the project is to i) apply cutting-edge microscopy methods coupled with biochemical analysis to study the molecular mechanisms regulating mitochondrial morphology, ii) investigate how mitochondria-organelle contact sites drive mitochondrial membrane remodelling and mtDNA dynamics, and iii) elucidate the relevance of these events to mitochondria and mtDNA quality control, as well as to inflammation and to human disease.

The 2020 Beirut explosion highlighted the need for a unified approach to blast load prediction and structural damage assessment. Our current inability to accurately predict blast loading in such environments limits advancements in structural damage predictions in real settings. Our aim is to raise the scientific benchmark of these linked but currently disconnected disciplines, and in doing to generate tools and frameworks to strengthen links along the entire event chain: detonation, to blast propagation, to loading development, to structural damage.

Under the EPSRC-funded “MicroBlast” project, colleagues at Sheffield University will perform scaled experiments to replicate the 2020 Beirut explosion, generating detailed, data-rich loading maps to supplement connected studies into structural damage assessment.

This postdoctoral position will support Prof. Matt Lambon Ralph’s programme on the neurocomputational basis of semantic cognition and its disorders. Collaborating with colleagues in Madison-Wisconsin, Kobe and Cambridge, the post-holder will assist with the implementation of novel forms of representational decoding, apply these to ECoG and newly-acquired fMRI data, and relate them directly to implemented neurocomputational models of semantic representation.

Applications are invited for a 2-year Postdoctoral Research Associate (PDRA) position in Chemical Process Engineering under the supervision of Prof Erwin Reisner (Yusuf Hamied Department of Chemistry at the University of Cambridge).

The project will enable the tech-transfer of chemo-enzymatic photoreforming, where solar energy is used to upcycle plastic waste into hydrogen (H2) gas. Specifically, an integrated process will be designed and assembled, where PET plastic waste is first broken down by enzymes and then photo-catalytically converted into H2 gas.

The PDRA will oversee the assembly of a continuous flow process to demonstrate the commercial feasibility of this solar chemical technology at a kg plastic, m2 photoreactor scale under real sunlight irradiation over several days. The outcome of this project should be published in top tier academic journals and also generate novel IP to support the commercial aspirations of this project. The PDRA will design, assemble and connect an enzymatic waste pre-treatment chamber and solar reactors and work together with an enzyme engineer and a sustainable technology expert in a highly collaborative setting. The PDRA will thus complement existing expertise in the Reisner laboratory and bring a strong skill set and expertise in chemical and process engineering.

The Department of Computer Science and Technology is an academic department that encompasses computer science along with many aspects of engineering, technology and mathematics. We have a word wide reputation for academic research with consistent top research ratings. The Department has an open and collaborative culture, supporting revolutionary fundamental computer science research, strong cross-cutting collaborations internally and externally, and ideas which transform computing outside the University. Please follow the link at: https://www.cst.cam.ac.uk to find out more about our Department

We are looking for a Research Assistant/Associate to work on the project Automated Verification of Textual Claims (AVeriTeC), an ERC project led by Prof. Andreas Vlachos at the University of Cambridge starting in September 2024 or as soon as possible thereafter. The successful candidate will be based in the Natural Language and Information Processing group (http://www.cl.cam.ac.uk/research/nl/) at the Department of Computer Science and Technology. The project will focus on developing approaches enabling the verification of highly complex claims, which require multiple pieces of evidence. Particular focus will be paid to accompanying the verdicts with suitable justifications.

Dr Dickens and the Marciniak Group are seeking a postdoctoral fellow to drive innovation in a programme of research investigating triggers of alveolar epithelial dysfunction in familial forms of interstitial lung disease. You will work with novel alveolar organoids, creating patient-specific models which you will interrogate using innovative culture techniques, genetic manipulation and multi-omics analysis including proteomics and transcriptomics with a view to identifying novel therapeutic targets.

With the very generous support of the Krishnan Ang Foundation in association with Trinity College, the Urological Malignancies Virtual Institute (UMVI) within the CRUK Cambridge Centre at the University of Cambridge is pleased to seek applications for a new research group. We are especially interested in scientists focused on the biology and treatment of localised kidney, prostate or bladder cancer. Based in one of the associated laboratories of the UMVI, the junior group leader will be affiliated with Trinity College as a Trinity Research Associate and be a member of the Trinity Postdoctoral Society. The exceptional funding available provides full salary support for the group leader for five years plus funding for a postdoctoral Research Associate, a Research Assistant, a PhD student and consumables.

For this exceptional opportunity, we are seeking an ambitious researcher whose science will complement and synergise with our existing research programmes whilst bringing new approaches to strengthen our focus on (a) early detection of urological cancers and (b) multimodal treatment of high-risk urological cancers. You will be ready to lead your own research group or have already started a group and will be making an impact in your field through published work, innovative projects and a distinctive vision for your research. Applications received from Clinicians in the field of Urological Cancer at ST6 or above will be considered.

Working in the Space Photovoltaics research group within the Department of Materials Science and Metallurgy, under the supervision of Prof. Louise Hirst, you will develop methods for fabricating high-performance III-V photovoltaic devices for space power applications. This will include the fabrication of devices with epitaxially grown III-V films using planar device process techniques.

You will characterise the performance of these devices using precision optical and electrical measurements including dark IV, light IV, EQE and ellipsometry. You will perform optical and device simulation and correlate with measurements to interpret results, diagnose problems and iteratively improve performance.

The Milner Therapeutics Institute (MTI) is a purpose-built research institute at the University of Cambridge. The overarching vision of the MTI is to convert pioneering science into therapies. The newly established Functional Genomics Screening Laboratory (FGSL) at the MTI applies arrayed CRISPR screening to shed light into the mechanisms underlying tissue homeostasis and disease biology. Formed as a joint venture between Medical Research Council, AstraZeneca and the University of Cambridge, this new laboratory aligns with the MTI’s approach of breaking the mould in terms of how academia and industry interact.

We are recruiting up to five scientists with an interest in functional genomics to join the FGSL screening team. For this role (PR41800) we will be considering candidates who have more than 2 years postdoctoral experience. Those with less experience or are about to submit their PhD should apply for role (PR41799).

The Milner Therapeutics Institute (MTI) is a purpose-built research institute at the University of Cambridge. The overarching vision of the MTI is to convert pioneering science into therapies. The newly established Functional Genomics Screening Laboratory (FGSL) at the MTI applies arrayed CRISPR screening to shed light into the mechanisms underlying tissue homeostasis and disease biology. Formed as a joint venture between Medical Research Council, AstraZeneca and the University of Cambridge, this new laboratory aligns with the MTI’s approach of breaking the mould in terms of how academia and industry interact.

We are recruiting up to five scientists with an interest in functional genomics to join the FGSL screening team. For this role (PR41799) we will be considering candidates without a PhD, but with the equivalent experience and candidates in the process of submitting their PhD thesis or awaiting degree conferral. In the latter case, appointment would be at the level of Research Assistant, Grade 5, in the first instance. On reciept of PhD award, the appointee would move to Grade 7, Research Associate. Those with more than 2 years postdoctoral experience should apply for role (PR41800).

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Research Associate (Fixed Term)

Deadline : 30 June 2024

View details & Apply

Applications are invited for up to two post-doctoral research associate positions in the groups of Prof. Dame Clare P. Grey to use a combined theoretical and experimental approaches to understand ion dynamics and degradation in Li-ion battery electrodes.

The project will explore the factors that influence ion dynamics in electrode materials for Li-ion batteries. Li+ ion dynamics in the bulk of the materials, as well as through interfaces will be investigated. Degradation processes that occur during battery operation will be studied to gain insight into their mechanisms and potential mitigation strategies.

The successful candidates will use X-ray diffraction techniques to characterise battery materials and so experience in this field is essential. They will also make use of a variety of modelling/simulation methodos to rationalise experimental results; therefore, experience with density functional theory and/or molecular dyamics simulations is essential. Experience with nuclear magnetic resonance methods (MAS-NMR, PFG) and electrochemical methods, and methods to characterise lithium diffusion and transport are desirable. The projects will involve collaboration with other researchers, both international and within a UK-wide consortium, so the demonstrated ability to work as member of a team is essential.

Applications are invited for a Research Associate to work with Professor Ziad Mallat, Professor of Cardiovascular Medicine at the Victor Phillip Dahdaleh Heart & Lung Research Institute. The post-holder will work in collaboration with the group of Professor Sarah Teichmann and the group of Dr. Helle Jorgensen within a programme focussed on single-cell mapping of human coronary and carotid atherosclerosis.

The successful applicant will possess a PhD in a relevant subject such as biological science, have at least two years of post-doctoral experience, and have extensive “hands-on” experience of single-cell genomic techniques and strong expertise in bioinformatic analysis of single-cell data. Experience in the isolation and culture of primary immune cells, preparing and analysing samples using flow cytometry and other standard laboratory techniques is essential. Experience in in vivo pre-clinical studies would be favoured. Candidates must have a track record of research achievement, including peer-reviewed publications.

This postdoctoral position will support Prof. Matt Lambon Ralph’s programme on the neuropsychology of frontotemporal dementia and contrastive neurological groups (e.g., resection for temporal lobe epilepsy). The work will span neuropsychological and neuroimaging investigations of patients and combine these with functional and structural neuroimaging from the patients and healthy controls.

A Research Assistant or Research Associate (post-doc) position in AI and Neuroinformatics is available to work with Prof Zoe Kourtzi (Adaptive Brain Lab, University of Cambridge; https://www.abg.psychol.cam.ac.uk) and Prof Eleni Vasilaki (University of Sheffield).

The position will focus on developing AI-guided tools for understanding brain processes and improving early detection of brain and mental health disorders. This position is well-suited for candidates eager to develop and translate theoretical AI models into practical solutions that can be deployed in clinical settings.

The successful candidate will engage in developing AI models to synthesise and analyse diverse data sets, including brain imaging, genetic, cognitive, and epidemiological data. The research activity is at the core of a Wellcome Trust funded Innovator Award that brings together multidisciplinary experts in neuroscience, machine learning, clinical practice, clinical informatics with healthcare innovation (and pharmaceutical industry partners (AstraZeneca).

One or more positions exist for a Research Assistant/Associate, in the Department of Engineering, to work on a collaborative project between the labs of Máté Lengyel at the Computational and Biological Learning Lab, Department of Engineering, University of Cambridge (https://cbl.eng.cam.ac.uk) and Nathalie Rochefort at the Centre for Discovery Brain Sciences, University of Edinburgh (https://rochefortlab.co.uk/).

The post holder will be located in Central Cambridge, Cambridgeshire, UK.

The project studies the neural representation of perceptual uncertainty in mouse primary visual cortex and and ties together several threads of research recently developed in our labs, based on the following key publications (note that several are collaborative between our groups):

• Koblinger Á, Fiser J and Lengyel M. Representations of uncertainty: where art thou? Current Opinion in Behavioral Sciences, 38:150¿162, 2021.
• Orbán G, Berkes P, Fiser J and Lengyel M. Neural variability and sampling-based probabilistic representations in the visual cortex. Neuron 92:530-543, 2016.
• Padamsey Z, Katsanevaki D, Dupuy N, Rochefort NL. Neocortex saves energy by reducing coding precision during food scarcity. Neuron 110:280-296.e10, 2022.

Applications are invited for a Postdoctoral Research Associate (PDRA) in Italian History and Memory Studies, to work in the Italian Section, Faculty of Modern and Medieval Languages and Linguistics at the University of Cambridge, on the research project ‘Escape, Community, Resistance, Memory. Italian populations and Allied prisoners of war’.

The post is fixed term for 30 months, full-time, to start 1 October 2024 or 1 January 2025. Requests for flexible working will be considered.

‘Escape, Community, Resistance, Memory’ is a research project funded by a grant from the Monte San Martino (MSM) Trust. The MSM Trust is registered charity (no. 1113897; https://msmtrust.org.uk/) set up to celebrate and commemorate Italian civilians and communities who helped Allied prisoners of war during World War Two. In 2024, the Trust entered into an agreement to transfer the holdings of its historical archive to the Cambridge University Library.

We are looking for a medically qualified trainee in oncology to join an established, multidisciplinary team investigating cancer cachexia.

The post has an essential requirement for an experienced clinician with significant oncology clinical training, who also has experience in participant recruitment and a strong knowledge of “Good Clinical Practice” as it relates to clinical research. These requirements are essential as the studies are already open and running to a recruitment deadline.

Similarly, previous experience in relevant clinical research and detailed phenotypic characterization of participants is essential as the role involves undertaking human based studies, including test meals and measurement of energy expenditure.

This is an exciting opportunity for an ambitious researcher to join an internationally renowned research Unit and a team carrying out high profile work at the cutting edge of development and application of Bayesian methods to infectious disease epidemiology.

The post-holder will be part of Professor De Angelis’ team within the Population Health Theme at the MRC Biostatistics Unit (MRC-BSU). The project, funded by a Wellcome Discovery award in collaboration with the Universities of Oxford and Manchester and the UK Health Security Agency, aims to develop new methods to understand community transmission of respiratory infections using data from the Office of National Statistics (ONS) COVID-19 Infection Survey (CIS).

The ONS CIS is a unique household survey with longitudinal follow up of over 500,000 participants who were regularly swabbed for SARS-CoV-2 infection at over 10 million visits, with positive swabs sent for whole-genome deep sequencing. A subset of participants were additionally tested for RSV and influenza. Over 100,000 high-quality SARS-CoV-2 sequences are available, linked to data on behaviour, symptoms and vaccination status collected at each visit. The ONS CIS was regularly used to estimate prevalence of SARS-CoV-2 in the population to inform policy during the pandemic (e.g. https://bit.ly/4bL6mvu). However, these data remain under-utilised.

The project is in collaboration with the Department of Computer Science and Technology at the University of Cambridge and the UK Health Protection Agency (UKHSA), and aims to investigate use of machine learning for prediction of infectious diseases outbreaks. Using data from routine surveillance of respiratory infections in the first instance, the postholder will explore different approaches to blending existing ordinary differential equation-based mechanistic infectious disease models with modern deep learning approaches to develop predictive models of relevant epidemic data. Challenges include the relative scarcity of relevant training data, characteristic of epidemics, and the need to appropriately quantify uncertainty in the predictions.

The successful candidate will have a PhD in a strongly quantitative discipline, but applications from candidates close to submitting their PhD are also welcome. Familiarity with deep learning methodologies is essential, as is research experience in biomedical modelling and machine learning, statistical programming, an ability to produce high-quality academic writing, good communication skills, and an enthusiasm for collaborating with non-statistical scientists. Experience in infectious disease transmission modelling is highly advantageous. The successful candidate will be supported in their career development with formal courses and on-the-job training.

Are you ready to make a meaningful impact in the world of medical imaging? We have an exciting opportunity for 2 new roles at the University of Cambridge.

We are seeking top-tier talents to advance diagnostic imaging research by leveraging expertise in computer vision and image processing. You will be part of a supportive and inclusive work environment that values innovation and excellence. Additionally, you will collaborate with an international consortium of leading experts who value trust, communication, teamwork and compassionate.

Joining the University of Cambridge offers not only the chance to work on innovative science but also the opportunity to significantly impact patient care and healthcare outcomes. If you are driven by the desire to make a real difference and thrive in an environment of academic excellence, we invite you to bring your expertise to our esteemed institution.

We are looking for a full-time Research Associate to work closely with Dr Sanne van Neerven in Ben Simon’s lab at the Gurdon Institute, University of Cambridge. The Simons lab is co-located in the Gurdon Institute, a centre of developmental biology and cancer research in Cambridge, and the Department of Applied Mathematics and Theoretical Physics. The Institute provides a stimulating environment that promotes collaborative and interdisciplinary research. Its postdoc association encourages scientific and social interactions and provides career development and teaching opportunities.

The successful candidate will have a strong background in epithelial biology with a keen interest and aptitude for work on the mouse intestinal, skin or oesophageal epithelium, with experience in the manipulation, characterisation, and confocal imaging of epithelial tissues. Further experience in the collection and analysis of the single-cell RNA-seq data, the manipulation of mouse and/or human organoid culture systems, and/or clonal lineage tracing will be highly beneficial. You should have a PhD in a relevant subject or expect to obtain one shortly, a sound understanding of molecular biology and a strong publication track-record in cell biology. You will be expected to be able to work independently and interact well in a dynamic multidisciplinary environment.

Applications are invited for a Post-doctoral Research Associate/Assistant position in the group of Dr Sebastian Schornack (www.schornacklab.net, twitter: @dromius) at the Sainsbury Laboratory (SLCU), Cambridge University, to study plant cell and developmental processes underpinning microbial colonisation.

Our lab studies how evolutionarily conserved plant cell & development processes shape interactions with beneficial and detrimental intracellular filamentous microbes and how microbes modulate such processes.

For this advertised project position, we are looking for a plant cell biologist with a strong interest in the model system Marchantia and comparative studies with flowering plants.

The aim of the project is to understand plant processes for barrier formation, cell- and tissue function etc which enable or restrict detrimental and beneficial filamentous microbes. The plant immune system or microbiological work with the microbe are not the focus of this study.

Applications are invited for a Research Associate post on the project EQUATE, a new project that investigates how Artificial Intelligence (AI) could be made globally more equitable in the area of Natural Language Processing (NLP). This UKRI Frontier project was selected for funding by the European Research Council (ERC) and is led by Prof. Anna Korhonen. The goal is to investigate the challenges in the development of globally equitable language technologies and to design transformative approaches to overcome them.

Responsibilities of the successful candidate include research into the ethics of developing language AI. This requires carrying out research and developing ethical guidelines for data gathering, annotation and all aspects of language AI development in diverse application areas and socioeconomic and cultural contexts. The post holder will take part in performance evaluation, and dissemination of research findings.

We are seeking an ambitious and talented postdoctoral research associate to join our team at the CRUK Cambridge Institute (part of the University of Cambridge) to use comparative genomics to study the role of codon usage bias in gene regulation. This is an exciting opportunity to contribute to our goal of understanding gene regulation and genome organisation on an evolutionary timescale.

You will be part of a small team, led by Dr Susanne Bornelöv, which studies gene regulation using various approaches including machine learning, evolutionary genomics, and sequencing bioinformatics. Our team is funded by an 8-year Wellcome Career Development Award (https://wellcome.org/grant-funding/people-and-projects/grants-awarded/data-driven-methods-unravel-hidden-layers-genome).

Your project will use comparative genomics and transcriptomics to investigate the role of codon usage in gene regulation. You will lead the generation and analysis of sequencing data and carry out downstream bioinformatic analyses across a phylogeny of fruit flies. The ultimate goal is to understand how mRNA sequence contribute to mRNA stability and protein output, and how this shapes the genome over evolutionary time.

The post, funded by an industrial contract with Shionogi, is based in the CLiC (Cambridge Laboratory for research on impulsive and compulsive disorders) directed by Professor David Belin at the Department of Psychology of the University of Cambridge.

The successful candidate will join a highly active research group in which they will take part in a programme of research that aims to establish the therapeutic potential (and underlying mechanism of action) of two new small molecules for the treatment of drug (heroin, cocaine, alcohol) use disorder.

The successful applicant will work alongside a post-doctoral researcher and a PhD student with whom they will carry out longitudinal studies using innovative behavioural procedures combined with pharmacology, molecular biology and circuit neuroscience techniques.

The Rayner Laboratory at the Cambridge Institute for Medical Research is recruiting a Research Associate to develop and apply a microfluidic device to study the invasion of human red blood cells by Plasmodium parasites. You will fabricate and test different device designs using soft lithography, load them with Plasmodium infected red blood cells, and use video microscopy to follow uninfected and infected red blood cells as they traverse through the microfluidic channels. You will then use tracking software to monitor the speed and behaviour of different cell types as they move through the channels, and will feed into the design and development of this custom software. This is a complex project involving skills in both biophysics and parasite biology, with very short delivery timelines.

The successful candidate therefore must have extensive hands-on experience in all the core techniques – designing, making and testing microfluidic devices using soft lithography, culturing Plasmodium parasites specifically in the UK regulatory environment, ie under derogated CL3 conditions, and analysing video microscopy data visually and computationally. Your primary focus will be on carrying out outstanding academic research leading to impactful papers, providing substantial scope for innovation, creativity and scientific judgement.

The Rayner Laboratory at the Cambridge Institute for Medical Research is recruiting a Research Associate to work on a project that combines Plasmodium knowlesi parasite culture and experimental genetics to perform systematic screens to understand malaria gene function. Focusing on antimalarial drug resistance and mechanisms of action, you will perform large-scale random mutagenesis screens using piggyBac transposons and select for specific phenotypes using drug pressure or novel phenotyping platforms. As the project is already underway and has a short delivery timeline, we are looking for someone with extensive experience in the relevant techniques.

To hit the ground running, the successful candidate will need multiple years of experience specifically in culturing and transfecting Plasmodium knowlesi parasites using both random and targeted genetic approaches, in performing phenotyping and screening assays with Plasmodium knowlesi parasites, and in analysing and interpreting sequencing-related outputs from large-scale genetic screens. You will also have working knowledge of UK biosafety regulations and restrictions in order to allow you to work immediately in the CL3 malaria parasite culture laboratory. Your primary focus will be on carrying out outstanding academic research leading to impactful papers, providing substantial scope for innovation, creativity and scientific judgement.

Applications are invited for a postdoctoral Research Associate in Energy Innovation, Economics and Policy to support a research project funded by the Alfred P. Sloan Foundation (USA). The three-year project is entitled ‘Designing Public Institutions for Commercializing New Clean Energy Technologies’ and is focused on identifying and classifying institutional characteristics or models, of public programs effective at clean energy technology commercialization in the United States.

This project is joint between the Center for Environment, Energy and Natural Resource Governance (C-EENRG) at the Department of Land Economy at the University of Cambridge, and the Energy & Environment Policy Lab at the University of Berkeley’s Department of Environmental Science, Policy and Management. The Cambridge PI is Professor Laura Diaz Anadon, Professor of Climate Change Policy at the University of Cambridge, Fellow at C-EENRG and Research Associate at the Belfer Center of Harvard University and the UC Berkeley PI is Professor Jonas Meckling, Director of the Policy Lab and Climate Fellow at Harvard Business School.

We are seeking to appoint a postdoctoral researcher to better understand the role of cellular senescence as part of the lung tumour microenvironment and the interplay with ageing. The postdoc will be based in the laboratory of Dr Daniel Munoz-Espin, Group Leader in the Department of Oncology (Early Cancer Institute) at University of Cambridge and co-Director of the Thoracic Cancer Programme. This post funded by a Cancer Research UK (CRUK) Programme Foundation Award is available from April 2024.

Dr Munoz-Espin’s research programme aims to understand the mechanisms and processes that contribute to lung cancer initiation and progression, and how to use this knowledge for the development of more efficient therapeutic strategies in precision medicine. We are looking for highly motivated postdocs to explore the impact of a senescent microenvironment and the modulation of the immune system in lung carcinogenesis. Additionally, we will investigate dynamic changes of this process during natural ageing. Candidates must have a PhD in the biological/biomedical sciences, and significant experience working in cancer biology, immunology and/or cell senescence with animal models and clinical samples. Skills in managing mouse models and procedures is essential for this post. Experience in spatial multiplexed imaging, multiomics analyses, generation of organoids and/or computational skills will be evaluated positively. International training and/or interconnections with the research industry are desirable. Original publications in peer reviewed journal/s will be positively considered.

We are looking to recruit a post-doctoral researcher to work with the Centre for Endowment Asset Management (CEAM) of Cambridge Judge Business School. CEAM is a research and education centre based within Cambridge Judge. CEAM is dedicated to furthering research and understanding of investment management for long-horizon investors, with a particular focus on sustainable and responsible investing; corporate governance/voting; long-run risk and return in traditional and alternative asset classes; factor investing and asset allocation; and financial market history.

This role is designed for a post-doctoral researcher with a PhD in Finance and a focus on empirical methods, particularly in the areas of sustainable finance, responsible investing and/or biodiversity finance. The role will sit within the CEAM. The role holder will become a member of the CJBS Finance Subject Group and will work closely with the research faculty leading CEAM (Professor David Chambers, Professor Elroy Dimson, Professor Oguzhan Karakas, and Professor Pedro Saffi), developing, conducting and supporting research and data analysis of on-going and/or new research projects.

A position exists, for a Research Assistant/Associate in the Department of Engineering, to work on a research grant that looks to advance our understanding of embodied carbon and design in the built environment. This role will see the successful candidate working with Professor Orr to advance research in the field of construction and structural engineering. The post will focus on efforts to reduce whole life embodied carbon of built assets. The work undertaken will build on Professor Orr’s previous grants, in particular “MEICON” (www.meicon.net).

We invite applications for a Post-Doctoral Research Associate (PDRA) to join our team at the University of Cambridge. The post holder will join the recently established Cambridge Complex and Multihazard research group (CoMHaz) and be employed across the departments of Earth Sciences and Geography. There will be excellent opportunities for collaboration both within the university and with international partners.

Research Project: Landslides are one of the most damaging natural hazards, causing several thousand deaths each year, destroying critical infrastructure and inhibiting development. The multiplicity of triggers and vast areas susceptible to landsliding makes their forecasting a complex yet critical task. Satellite-based slope monitoring and landslide identification is one of the few plausible approaches to regional or national-scale landslide early warning.

A creative postdoctoral researcher with experimental or computational expertise is sought to work in Mark Howarth’s group on a project funded by MRC at Cambridge University Department of Pharmacology. The Howarth group have broad interests, including synthetic biology, biotechnology and entrepreneurship (www.howarthgroup.org). The project relates to engineering a protein superglue to enhance cell therapy of cancer. SpyTag is a genetically-encoded peptide created by the Howarth lab, which forms an irreversible covalent bond to its protein partner SpyCatcher. SpyTag provides a unique resource for molecular assembly and has been applied by >1,000 groups around the world for basic research and biotech, as well as reaching clinical trials. This project will devise a new generation of Tag/Catchers that are camouflaged to the immune system, so are much more potent for therapeutics. Collaborating with Imperial College London, we will apply this new protein superglue to overcome major barriers to cost-effective and potent CAR-T cell therapy against lymphoma. This technology will also be a powerful advance for antibody, gene therapy and vaccine approaches under development by the group.

Our group consists of PostDocs and PhD students investigating performance, reliability and security in future many-core systems. The position is within the Computer Architecture Research Group at the University of Cambridge Computer Laboratory in a joint project with Arm; there will be frequent interaction with Arm and the ability to work in Arm’s offices in Cambridge for durations of the project. Collaboration with researchers at other universities and industry around the world is encouraged and there are strong links within the group with other local companies.

We seek candidates with a strong background in Computer Science with a particular interest in computer architectures and compilers. It is essential to have experience in program analysis for identifying parallelism opportunities, in developing microarchitectures for exploiting parallelism in high-performance processors and in creating schemes within simulators such as gem5 or another tool. Familiarity with working in teams with robust engineering practices (version control, continuous integration, automated testing) would be useful. The ideal candidate would have an awareness of the challenges and potential solutions to parallelism extraction.

A position exists for a “Post Doctoral Research Associate” in the Department of Pure Mathematics and Mathematical Statistics funded by a grant held by Prof. Ailsa Keating.

Applicants should have a PhD in a relevant field, a strong research track record, and may have previous postdoc experience. Candidates should have expertise in at least one of the following: symplectic geometry, mirror symmetry, singularity theory, geometric group theory; or have training in the parts of algebraic geometry/representation theory related to Bridgeland stability conditions, cluster algebras and quivers.

Duties include developing and conducting individual and collaborative research objectives, proposals, and projects. The role holder will be expected to plan and manage their own research and administration, with guidance if required, and to assist in the preparation of proposals and applications to external bodies. You must be able to communicate material of a technical nature and be able to build internal and external contacts. You may be asked to assist in the supervision of student projects, the development of student research skills, provide instruction, or plan/deliver seminars relating to the research area.

A position exists, for a Research Assistant/Associate in the Department of Engineering, to work on research in the fields of machine learning, hydrology, and water resources management at various spatial scales, from river basin to global.

The post holder will be located in Central Cambridge, Cambridgeshire, UK.

The key responsibilities and duties are:

• Explore alternative ML models for hydrological prediction, focusing on large river basins in Africa, Asia and South America
• Assemble and harmonize large sets of hydro-climatic data
• Contribute to research proposals and writing bids for research grants
• Write peer reviewed academic publications of the highest standards of significance and impact
• Supervise less experienced researchers and PhD students
• Develop skills and networks to become a successful independent researcher, including through grant writing, independent papers, consulting, trainings.