12 Postdoctoral Fellowship at Saint Louis University, Missouri, USA

Saint Louis University, dedicated to student learning, research, health care, and service, is seeking applicants for a Postdoctoral Fellow in Dr. Guangyong Peng’s lab in the Departments of Internal Medicine and Molecular Microbiology and Immunology. This is a grant supported position focused on the study of “Metabolic Control of T Cell Senescence in Pathogenesis and Immunotherapy of Alzheimer’s Disease.” The Peng laboratory has been performing the translational studies to dissect molecular mechanisms responsible for the senescence and dysfunction of T cells in different diseases, including cancer and age-related neurological disorder (Alzheimer’s Disease), and then to develop effective strategies for molecular and metabolic control of T cell fate and function for disease prevention and immunotherapy.

Saint Louis University, dedicated to student learning, research, health care, and service, is seeking applicants for a Postdoctoral Fellow in Dr. Guangyong Peng’s lab in the Departments of Internal Medicine and Molecular Microbiology and Immunology. This is a grant supported position focused on the study of “Metabolic Control of T Cell Senescence in Pathogenesis and Immunotherapy of Alzheimer’s Disease.” The Peng laboratory has been performing the translational studies to dissect molecular mechanisms responsible for the senescence and dysfunction of T cells in different diseases, including cancer and age-related neurological disorder (Alzheimer’s Disease), and then to develop effective strategies for molecular and metabolic control of T cell fate and function for disease prevention and immunotherapy.

The Cifarelli Lab at SLU School of Medicine is seeking a motivated postdoc to work on a NIH funded project examining the role of lipids in vascular and lymphatic endothelial cell biology and its connection to gastrointestinal health and inflammation. Candidates must have a PhD or MD with an interest in cellular/molecular cardiovascular or gut research. Eligible candidates should email a CV including publications and the names of 3 professional references, and a brief statement of research with career plan to [email protected]

The Postdoctoral Fellow will assist the Principal Investigator. The incumbent will conduct research and ensure that all experiments are appropriately conducted following the policies and procedures of Saint Louis University. A postdoctoral or Research Fellow position is available immediately to conduct cryo-EM studies of coagulation factors and their complexes (visit https://biochem.slu.edu/faculty/dicerawp/). Documented experience with X-ray crystallography and cryoEM is required. Please send a CV by email to [email protected]. 

This position is funded by an NSF project titled “Collaborative Research: CPS: TTP Option: Medium: Sharing Farm Intelligence via Edge Computing”. The project will develop a cyber-physical system, a novel data processing platform, that integrates remote sensing, computer vision/photogrammetry, AI, plant phenotyping, computer networking and privacy. The initial appointment is for one year and can be renewed for the second year contingent upon funding availability and satisfactory performance evaluation. The postdoc candidate is expected to catalyze collaborations among the PIs and jointly supervised Drs. Vasit Sagan, Flavio Esposito, Nadia Shakoor, Reza Tourani, and Kate Holdener.

A postdoctoral position is immediately available for exceptionally motivated and creative individuals in the laboratory of Dr. Anutosh Chakraborty at Saint Louis University, Missouri. Using a system biology approach, the Chakraborty lab aims to understand molecular mechanisms that regulate development and progression of obesity, insulin resistance and NAFLD/NASH. Prior work from the lab established that the enzyme inositol hexakisphosphate kinase-1 is a target in metabolic diseases. The current focus is to define functions of a novel ubiquitin ligase in these diseases using knockout mouse models and pharmacologic tools. The postdoc will be primarily responsible to determine role of this ligase in lipid accumulation, endoplasmic reticulum stress, metabolism, and survival of hepatocytes in vitro and in vivo. He/she will also be engaged in identifying/validating ubiquitination targets of this ligase in these processes. Candidates with a solid background in ubiquitination, molecular/cellular biology and biochemistry and a strong publication record in the areas of ubiquitination, obesity, and/or NAFLD/NASH are encouraged to apply.

Saint Louis University is a Catholic Jesuit Institution dedicated to student learning, research, health care and service. This Postdoctoral Fellow position is in the chemistry research group led by Dr. Istvan Z. Kiss in the Department of Chemistry (https://www.slu.edu/artsand- sciences/chemistry). This work involves modeling 2D and 3D corrosion spreading and formulation of mitigation strategies using morphological feedback.

A postdoctoral position is available immediately in the lab of Gucan “Gabriel” Dai at the Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine. Candidates with a strong publication record in biophysics and biochemistry in ion channels or membrane proteins are encouraged to apply. Past experiences in patch-clamp electrophysiology or fluorescence cell imaging using advanced microscopy are preferred but not required. The Dai lab combines structural biology, chemical biology, genetics, fluorescence microscopy and electrophysiological methods to understand the fundamental mechanisms underlying ion channels of excitable membranes. The candidate is expected to publish high-impact papers as a lead author and apply for academic faculty positions or leadership positions in industry after receiving this training. The research directions in the lab are summarized in below. Applicants who are interested in this position should contact: [email protected] 

Our NIH-funded laboratory is seeking an enthusiastic postdoctoral fellow to study the immunological response and pathogenesis of viral infections. Laboratory studies are focused on the understanding of the antigen specific B cell response to infection and vaccination and how this B cell response is reflected in the polyclonal antibody response. Our laboratory uses in vitro and in vivo approaches to understand infection and disease.  Techniques include cloning and molecular biology, biochemistry, cell/tissue culture, flow cytometry, transcriptomics, and mouse models of infection. Experience in one or more of these techniques and areas is strongly preferred. You will be provided with the mentorship and resources to be successful.

Saint Louis University, dedicated to student learning, research, health care, and service, is seeking applicants for a Postdoctoral Fellow in Dr. Jianguo Liu’s lab in the Departments of Internal Medicine and Molecular Microbiology and Immunology. Tuberculosis (TB) remains a leading health problem worldwide. The lack of highly effective preventive vaccine, the emergence of drug-resistant strains, and an epidemic in HIV patients make TB a worsening threat. Host-directed therapy (HDT) is a promising approach for treating drug-resistant TB. This NIH-funded position is to investigate the host protective immune mechanisms and develop new HDT against Mycobacterium tuberculosis infection.