22 Postdoctoral Fellowship at University of British Columbia, Canada

The two postdoctoral fellows (PDF1 and PDF2) will work in close interaction and be part of a larger UBC team. As guiding features, we expect the candidates to be very motivated, open to learning and adapt to interdisciplinary interactions and challenges; their roles and expertise should be complementary, to enable the development of a successful project. We expect the project to grow in time beyond the framework of the presently funded context and to enhance collaboration with different organizations.

PDF1 is required to have a good background in sensors, sensor networks, circuits, embedded systems, and wireless communications. He will coordinate the development of sensor modules to be placed on the ground and dropped by surveillance drones, discuss and plan together with the team the sensor network grid, how the input from the modelling effort will influence the practical strategy, how the data is collected, in an effective and efficient manner. The work is expected to be a balance between the system design, manufacturing and experimental tests performed in collaboration with team members and firefighter teams.

PDF2 will handle data fusion aspects – how to integrate sensor data and extra available information (satellites maps, landscape and ground characteristics, etc.) in a way suitable for the modelling and simulation, analyze the sensitivity of the model to various inputs and how to handle model predictions in the context of various levels of required responses by the firefighter teams.

The two postdoctoral fellows (PDF1 and PDF2) will closely interact and integrate within the UBC team. They should be both very motivated, open to learn and adapt to interdisciplinary interactions and challenges, and their complementary expertise will enable the development of a successful project, with wide future perspectives.

PDF1 is required to have a strong background in microfabrication , MEMS technology, microtransducers design, simulation and fabrication and testing. His role is to develop a custom polyCMUT array for spinal cord imaging.

PDF2 needs a good expertise in sensor interfaces, circuit design, general analog and digital electronic systems and signal processing. His role is to integrate the ultrasound transducer array with custom electronics and to ensure the interface with a backend ultrasound imaging system. Their activity will be supported by other researchers and graduate students in the team.

Dr. Lucia Nappi and Dr. Martin Gleave lead the GUNS study, a genomic-driven neoadjuvant clinical trial that is currently enrolling patients with localized prostate cancer to receive targeted agents and androgen deprivation therapy on the basis of genomic sequencing of the prostate biopsy. The pre and post-treatment tissue and blood samples will be used for genomics, transcriptomics and epigenomics to identify the molecular drivers of treatment response or resistance to standard and experimental drugs.

The Vancouver Prostate Centre seeks a talented postdoctoral fellow in Computational Biology who will work with Drs. Gleave and Nappi. The successful candidate will work on the analysis of datasets generated from prostate cancer genome sequencing, RNA-sequencing, DNA methylation profiling and ChIPseq data, in order to help advance efforts for precision cancer medicine in prostate cancer.

The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patient tissues and patient-derived xenografts (PDX). The lab is highly multidisciplinary and highly productive (Laks et al, Cell 2019, Salehi et al Nature 2021, Funnell et al Nature 2022) and is well funded for single cell analysis of genomes and transcriptomes in cancer. The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patients and patient-derived xenografts. The project involves collaborating on an exciting project mapping clonal dynamics in human cancers under drug treatment with new single cell methods. The post holder will also have the opportunity to interact as part of the international Welcome LEAP Delta Tissue project and an exciting new program in the biology of epithelium from high risk carriers of BRCA1/BRCA2 mutations. These projects are bringing new measurement methods and computational techniques to the 3D reconstruction of tumours, and mapping drug sensitivity and drug combinations using sgRNA/CRISPR methods in vivo. The program works closely with UBC departments of statistics and computer science and the New York Genome Center NY, on the development of new models for single cell data and cancer evolution. Some experience with bioinformatics approaches to biological data and familiarity with handling of genomics data will be an advantage.

Successful applicants will be expected to conduct primary research in one or more areas of ocean data acquisition, analysis and modelling, working under the co-supervision of at least two faculty researchers. Research topics of interest include, but are not limited to: ocean mixing, biogeochemical cycles, geophysical processes along oceanic plate boundaries, coastal dynamics, use of autonomous ocean sensors, and the development of numerical models and statistical methods for ocean data analysis and forecasting. For this call, we seek candidates for two distinct projects, as outlined at the end of this document under PROJECT DESCRIPTIONS.

A postdoctoral/research fellow position is available, working on an exciting international project to define additional mechanisms and target engagement of G4 ligands in cancer genomes, utilizing single cell sequencing and chemical biology methods. The Aparicio lab is developing small molecule ligands of G-quadruplex structures in DNA as a therapeutic, based on recent success from the lab demonstrating for the first time clinical proof of principle (Hilton et al, Nat. Comms 2022) for a G4 binder. The Aparicio lab is multidisciplinary environment, highly productive (Laks et al, Cell 2019, Salehi et al Nature 2021, Funnell et al Nature 2022, aparicio.molonc.ca for projects and papers) and is well funded for single cell analysis of genomes and transcriptomes in cancer. The labs has created and practices methods for sequencing single genomes, defining epigenetic states in single cells and mapping gene fitness in vivo (Eirew et al, Nat. Comms 2022). The post holder will also have the opportunity to interact as part of the international Welcome LEAP Delta Tissue project and an exciting new program in the biology of epithelium from high risk carriers of BRCA1/BRCA2 mutations. The program works closely with UBC departments of statistics and computer science and the New York Genome Center NY, on the development of new models for single cell data and cancer evolution. Some experience with bioinformatics approaches to biological data and familiarity with handling of genomics data will be an advantage, beyond core experience of molecular biology and drug target biology in cancer.

The successful candidate will work under the supervision of Dr. Gregory Paradis and collaborate with Dr. Hisham Zerriffi, Dr. Taraneh Sowlati, and Dr. Qingshi Tu to model the forest-based biomass supply solution space in British Columbia. The research project will lay the foundation for a long-term research partnership on sustainable bioenergy production, with linkages to larger-scope issues around sustainable development of the forest and bioproducts sectors.

One postdoctoral position is available to join an energetic and collegial group dedicated to enhancing the health of children with diabetes. The successful applicant will work at the BC Children’s Hospital Research Institute on this exciting collaborative project directed by Dr.Angela Devlin and Dr.Dina Panagiotopoulos. The project will involve molecular phenotyping of children with diabetes and understanding the pathophysiology and progression of cardiovascular complications in children with type 1 diabetes. The Devlin and Panagiotopoulos labs are located within the Childhood Diabetes Laboratories at BC Children’s Hospital Research Institute and are part of the provincial BC Diabetes Research Network (diabetesbc.ca).

A postdoctoral position in the area of cellulose and carbohydrate polymer chemistry is available immediately in the Sustainable Functional Biomaterials lab at the University of British Columbia, Vancouver, Canada. The objective of this position is to chemically modify cellulose and nanocellulose with enhanced hydrophobicity. A suite of  technologies including surface modification and functionalization, nanomaterials synthesis and characterization, and surface and coating engineering, are expected to be developed as the main job responsibilities

At Mérida Labs, we are looking for a motivated and solution-oriented postdoctoral fellow. Our group focuses on integrated energy systems research that encompasses breakthrough technologies, policy, energy conversion, new business models, techno-economic and life cycle analyses, machine learning, optimization, AI, intelligent networks, among others.

The role will focus on a project in partnership with InDro Robotics, Rogers, Canada Post and Honeywell. The first objective is to develop a last mile parcel delivery modelling that optimizes the control, routing, and operation for zero-emission ground and aerial vehicles. As the team leader, you will have the opportunity to develop this line of research, where you will also support and mentor student teams, and identify ways to expand the relationship with our partners and the research goals.

The University of British Columbia’s Department of Physics and Astronomy and TRIUMF are seeking applications from recent particle physics graduates interested in a Postdoctoral position with the Rare Decay Group at TRIUMF. TRIUMF is Canada’s particle accelerator centre, and one of the world’s leading laboratories for particle and nuclear physics and accelerator-based science. TRIUMF is  an international centre for discovery and innovation, advancing fundamental, applied, and interdisciplinary research for science, medicine, and business.

The Fellow will be expected to design and implement studies under the supervision of the Principal Investigator, while also contributing to existing studies. Focus will be on quantitative research projects, including: (1) an administrative-linked cohort study evaluating slow-release oral morphine as opioid agonist therapy; and (2) a cohort study evaluating injectable opioid agonist therapies in Vancouver. This post will suit recent PhD graduates with strong research skills who are seeking to advance an academic career in public health and health services research. The Fellow will be responsible for preparing grant and fellowship applications, and analysing and writing up existing data, working under the direction of the Principal Investigator. The Fellow will play a role as needed in coordinating program activities, maintaining research records, and contributing to the management and analysis of data.

The Canadian group in the DarkLight collaboration has an immediate opening for a postdoctoral researcher to join us in a search for new bosons in the mass range from 10 to 20 MeV using the TRIUMF/ARIEL e-linac. The successful applicant will join a small international collaboration and be based at TRIUMF in Vancouver, BC. The brief and intense schedule for the DarkLight experiment means that this position provides a unique opportunity for a young postdoctoral researcher to participate in a particle physics experiment from the design stages right through data taking to a final result during their time at TRIUMF.

The mission of the Cassie & Friends International Postdoctoral Fellowship in Pediatric Rheumatology is to provide training to PhD researchers in the field of pediatric rheumatology and to support future investigative careers in the improved understanding of rheumatic diseases. The rheumatic disease family is a collection of multiple diseases that include the more commonly known juvenile idiopathic arthritis (JIA), rarer conditions like vasculitis and systemic lupus erythematosus (SLE), and a relatively new group of autoinflammatory diseases. Despite genetic and phenotypic differences, all rheumatic diseases are characterized by relapsing and remitting episodes of pain and inflammation. They provide a clear example of morbidity and disability that results from immune dysregulation and uncontrolled inflammation. One of the major challenges in the management of childhood rheumatic diseases is to balance the risks associated with therapy against the risks associated with either undertreating aggressive disease or over-treating less aggressive disease. This is particularly problematic in children as there are few, if any, treatments that are specific and safe for a growing child. The successful candidate will lead investigative efforts towards the improved understanding of immunological mechanisms of childhood rheumatic diseases that will aid diagnosis and therapeutic decision making. The fellow will be offered an appointment through the University of British Columbia (UBC, Vancouver, BC) Department of Pediatrics. The initial term will be for 1 year commencing no later than Jan 2023, with a possibility for extension for a second year. Research will be conducted at the British Columbia Children’s Hospital Research Institute (BCCHRI, also in Vancouver, BC) under the supervision of Dr. Kelly Brown. This is a highly dedicated and collaborative research environment in which the candidate will interact regularly with clinicians and scientists in the Division of Pediatric Rheumatology at British Columbia Children’s Hospital.

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: POSTDOCTORAL FELLOWSHIPS IN MONITORING PATIENTS IN EMERGENCIES AND DISASTERS

Deadline : 31 May 2023 –

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Professors Robin Turner and James Piret invite applications for a full-time post-doctoral fellowship position available in the field of bioanalytical Raman microspectroscopy and Raman chemical imaging.  We seek a highly qualified individual with a doctoral degree in chemistry or physics or engineering with an interest in developing process analytical technologies for cell therapy bioprocess applications.  Essential qualifications include experience measuring and analyzing Raman spectra of live or fixed cultured cells using a commercial Raman microspectroscopy instrument and common multivariate chemometric methods (e.g., principal component analysis).  Experience with MATLAB and LabVIEW software applications would be an asset.

We are looking for a postdoctoral fellow who will strive to make a meaningful impact on maternal and child health by contributing to leading-edge research aimed at improving pain management.

Pain management is often under-emphasized, yet inadequate pain relief can interfere with a mother’s ability to care for her child, and can disrupt sleep, impact behaviour and cause vomiting in children. In light of the current opioid crisis, there is increased urgency to balance both safety and effectiveness of opioid-based analgesics, while simultaneously limiting the use of opioids. Given the resulting hesitancy associated with prescribing opioids, we are likely undertreating pain in women and children.

At Mérida Labs, we are looking for a motivated and solution-oriented postdoctoral fellow. The project is in partnership with Indro Robotics, Rogers, and Canada Post. InDro Robotics is a Canadian company focused on providing innovation in aerial robotics to enable complex operations, data collection, surveillance, and delivery services. 

A postdoc fellowship position is available in Dr. Xuesen Dong’s lab at Vancouver Prostate Centre (VPC), University of British Columbia. The VPC has a large number of multi-disciplinary research programs in basic, clinical, and translational cancer research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority.