29 Postdoctoral Fellowship at King’s College London, United Kingdom

The Fellow will be part of the Department of Twin Research and Genetic Epidemiology. The Department is based at St. Thomas’ Hospital in the School of Life Course Sciences, Faculty of Life Sciences and Medicine at King’s College London. The Fellow will have an honorary contract of employment with Guy’s and St Thomas’ NHS Foundation Trust. The Fellow will undertake recruitment of older patients undergoing elective colorectal cancer surgery (with or without subsequent systemic anti-cancer treatment) to a clinical study with follow-up assessments postoperatively. The study is part of a global initiative in experimental and translational medicine to accelerate interventions to prevent and treat loss of resilience amongst older people. The Fellow will receive training and supervision in the conduct of musculoskeletal ultrasound, electroencephalography assessment (not including interpretation), and comprehensive assessment of older people across multiple settings. The full study protocol and ethical approval will be finalised prior to commencement of the Fellow to this post.

This is an exciting opportunity for a post-doctoral researcher passionate about Patient and Public Involvement and Engagement (PPIE) in research to make a difference in the National institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre (BRC) for Mental Health. Our NIHR Maudsley BRC believes in putting the service user voice at the heart of research, and generating knowledge that will make a difference to the lives of people affected by mental distress. Within the PPIE theme, we put this into practice by supporting service user involvement activities and conducting research that matters to service users. Our previous research has included measures like one to report medication side effects and we hope to develop more of these Patient Reported Outcome Measures (PROMs).

We are seeking to appoint a Post-Doctoral Research Associate in Behavioural Interventions to join the School of Population Health Sciences. This position is to enhance our research capabilities, particularly with a focus on digital therapeutics and health services research.

As a Post-Doctoral Research Associate, you will support our on-going research in the field of digital therapeutics and health services. Your primary focus will be on conducting and supporting the delivery of high-impact research. Responsibilities include:

• Lead and conduct research in behavioural interventions, digital therapeutics, and health services, aiming for publication in top-tier journals
• Develop and apply innovative behavioural intervention strategies within digital health platforms, assessing their impact on health outcomes
• Foster collaborative relationships and engage in networking activities to bolster partnerships within the digital health ecosystem
• Play a key role in the implementation of behavioural interventions, significantly contributing to the advancement of digital health research at our institution

The purpose of the role is to coordinate a research project (ACDI) aiming to evaluate the implementation of Advance Choice Documents (ACDs) for people previously detained under the Mental Health Act (MHA) throughout the South London and Maudsley NHS Foundation Trust (SLaM). The project is co-led by Professor Claire Henderson and Dr Shubulade Smith.

Completing an ACD involves stating, in advance, aspects of your care, including preferences, wishes for and refusals of certain types of treatment when one is well enough to do so. These preferences can be used to guide the care when a person is unwell and does not have the capacity to make decisions about their treatment.  The UK government has committed to legislating for advance statements (www.gov.uk/government/consultations/reforming-the-mental-health-act/reforming-the-mental-health-act). This commitment is based on ethical and legal arguments along with research evidence that creating such documents (variously termed joint crisis plans, advance statements and psychiatric advance directives) can reduce use of involuntary admissions and improve therapeutic relationships.

The Department of Political Economy is seeking to appoint a Postdoctoral Research Associate to work full time on the research project ADVODID with Anne Rasmussen.  The Advocacy in Digital Democracy (ADVODID) project is funded by an European Research Council Consolidator Grant. It seeks to implement the first large-scale project designed to provide evidence on the effects of advocacy on citizens and policymakers in both online and offline settings. It analyzes the use, impact and democratic consequences of digital advocacy strategies by assessing interactions of advocacy groups, citizens and political representatives in eight countries (potentially Australia, Chile, Denmark, India, the Netherlands, Spain, the UK, and the US). The project sets out to address – theoretically and empirically – the potentials and challenges for modern democracies that arise from digital advocacy tools. 

The successful candidate will have a strong interest in cancer biomarker research and will be part of a multi-disciplinary team of cancer researchers, cell biologists, and imaging scientists. The post holder will be designing and performing a variety of in vitro, in vivo, and ex vivo experiments in close collaboration with other team members. Importantly, it is a requirement of this project to collaborate with existing teams of scientists with diverse backgrounds inside and outside the department, in particular with colleagues providing specialist tumour models, antibody developers, and animal technicians. The post holder will have access to cutting-edge technologies including antibody validation platforms, patient-derived tumour models, and quantitative whole-body tumour and ImmunoPET imaging alongside access to a variety of state-of-the-art King’s facilities such as those for flow cytometry, advanced microscopy, and preclinical tumour models. The role involves work at different CR-UK City-of-London Centre Campuses as required by experimental requirements. 

The Department of Political Economy is seeking to appoint two Postdoctoral Research Associates to work full time on the research project DERISK with Steven Klein. The Systemic Risk and the Transformation of Democracy (DERISK) project is funded by a UKRI Frontier Research Grant (successfully evaluated for the ERC Starting Grant and funded by UKRI as part of the UKRI Horizon Europe guarantee). From financial crises to climate change and pandemics, over the past several decades societies have increasingly faced systemic risks. Drawing together political philosophy, the philosophy of risk, and empirical research on systemic risk in political science, sociology, economics, risk studies, and complexity theory, the project asks: what happens to democracy when systemic risks become a central problem of politics? And how should democratic institutions govern these new forms of risk? 

The Levitated Nanophysics Group in the Department of Physics is looking to recruit a post-doctoral research assistant to join their diverse and dynamic team. The successful candidate will join a group at the heart of the global levitated nanoparticle research community, and a key player in the UK’s Quantum Technologies landscape. See www.levi-nano.com for more details. 

The Department of Physics at King’s College London is diverse, international, and friendly with a positive atmosphere of collaboration and support between research groups. We offer a welcoming environment and welcome applications from applicants of all backgrounds.  

The successful candidate will work closely with Dr. James Millen on the theory and simulation of thermodynamic processes at the microscale, supporting a parallel experimental effort in the application of levitated microparticles for analogue simulation. The candidate will have the opportunity to shape the research agenda of the project, explore their own ideas, and work with a wide pool of collaborators from the physical, mathematical and biological sciences. 

A vacancy for a Postdoctoral Research Assistant to work on a new R&D activity  developing and testing quantum sensor readout of Xe-based dark matter detectors has arisen at the Experimental Particle and Astroparticle Physics (EPAP) Group, Department of Physics, King’s College London.   

We will welcome the successful candidate into the diverse Experimental Particle and Astroparticle Physics (EPAP) Group, to undertake research investigations in collaboration with the members of the EPAP group, and with close links to the Biological Physics and Soft Matter group at King’s as well as with project partners at the University of Glasgow. We especially encourage applications from females, minority ethnic candidates and other groups who are under-represented in physics. 

We have postdoctoral Research Associate positions available in the Spagnoli lab. in the Centre for Gene Therapy and Regenerative Medicine at King’s College London. Our team uses interdisciplinary approaches for studying pancreas development and islet cell engineering from stem cells. The candidates will be part of a T1D Grand Challenge-funded research programme aiming at harnessing the islet microenvironment in all its complexity for stem cell therapy of diabetes.

This is an exciting interdisciplinary research programme that will require expertise in stem cell culture, human tissue, bioengineering, computational analytical methods and islet transplantation. Applicants should have a recent Ph.D. degree or have submitted his/her Ph.D. thesis. We wish to appoint highly motivated individuals: one PDRA with background in development and stem cell biology and one PDRA with background in stem cell biology and animal model transplantation.

The Odendall Laboratory studies both sides of interactions between the host and enteric bacterial pathogens. We seek to understand the interplay between the bacteria Salmonella and Shigella and type I and III interferons (IFNs).

Type I and III IFNs are induced, along with other cytokines, upon detection of microbes. They have a direct effect on the tissue, inducing hundreds of interferon-stimulated genes (ISGs), with diverse antimicrobial functions. While the functions of type I/III IFNs in antiviral immunity are extensively studied, if/how IFNs and their ISGs protect against bacterial infection is poorly understood.

We have recently reported that bacterial factors translocated by the Shigella type III secretion system (T3SS) block IFN receptor signalling (Alphonse et al, Cell, 2022), and the induction if ISGs. This suggests the importance of this pathway in host defence against bacteria. Indeed, IFNs were protective against Shigella infection in cellular and animal models of infection.

The successful candidate will have a PhD in immunology, be hardworking, with a proven track record of publication as a primary author of scientific paper(s) in well-regarded scientific journals. They should have a particular interest in tackling fundamental questions regarding host-pathogen interactions.

The main purpose of this role is to undertake high quality research into interrogating the evolutionary divergence of nuclear envelope organisation and remodelling and assist the PI in driving research in the lab. The research project involves a range of quantitative cell biology methodologies together with molecular biology, omics, lab evolution and biochemistry approaches in the two species of fission yeasts, S. pombe and S. japonicus.

You should have extensive expertise in fission yeast molecular genetics and fluorescence microscopy, including confocal microscopy, together with image processing and analyses. The appointee is expected to be experienced in functional genomics (e.g., RNA-seq), structural genomics (e.g., Micro-C chromatin capture) and associated bioinformatic analyses. You should be experienced in molecular biology methods, including molecular cloning, DNA and RNA extraction and handling, qPCR, etc.

This one-year post funded by Cancer Research UK is focusing on the analysis of the tumour immune microenvironment in ductal carcinoma in situ (DCIS) and invasive breast cancer using spatial transcriptomics, with the aim of identifying a signature of radiation resistance in breast cancer.

The post holder will be based in the Guys Cancer Cancer Centre (Innovation Hub), School of Cancer & Pharmaceutical Sciences, Kings College London and be part of the Molecular Breast Cancer Genetics Group led by Professor Elinor Sawyer.

Radiotherapy is routinely used in the treatment of breast cancer to reduce the risk of recurrence. However, despite radiotherapy some patients still experience local recurrences, and this is associated with worse long-term outcomes.

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Research Associate (Quantitative Data) in the Department of Health Services & Population Research

Deadline : 11 April 2024

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This is an exciting opportunity for an experienced researcher to complete recruitment for the CRISP study (Clinical Response of Impulsivity after Brain Stimulation in Parkinson’s disease). The study aims to answer the research question ‘Which factors are important in predicting changes in Impulse Control Behaviours (ICBs) following Deep Brain Stimulation (DBS) for Parkinson’s disease (PD)?’

The RADlab at King’s College London is seeking to recruit a Postdoctoral Researcher for the Neural-driven, Active, and Reconfigurable Mechanical Metamaterials (NARMM) project. The project aims at developing the first generation of reconfigurable and shape-shifting robotic matter for wearable robotics, with large potential for high impact publications and science advances. The Project is in collaboration with Harvard University, MIT, University of Luxemburg, Bristol University, City University of New York and five industrial partners, with the possibility to carry out exchange visits and secondments. The RADlab is a state-of-the-art facility in the centre of London (Strand Campus), based within the King’s Engineering Department.

This post holder will join an exciting project team which brings experts from Social Gerontology, Psychology, Design, Smart Composite Material, and Artificial Intelligence to shape a world class consortium of universities, industries, NGOs and policy makers. The successful candidate for this role will join an interdisciplinary research group and be supervised by Professor Wei Liu.

Jointly funded by EPSRC and NIHR, this £1.5m ‘DELONELINESS’ project aims to design a smart monitoring and communication system with multifunctional electronics built into textiles used as wearables and home furniture to measure loneliness levels in older people. Refining methods of identifying loneliness in those who are isolated will allow timely and effective intervention. This project is led by King’s College London in collaboration with University of Leeds and University of Sussex.

This is a project funded by UKRI and Innovate UK. The project received an extension of 5 months to allow the collaboration with Medicines Discovery Catapult. In this project King’s College London collaborates with Apeikon Therapeutics and Pharmidex to deliver a novel technology that aims to deliver safe and efficient brain cancer treatments. King’s is looking to recruit a scientist that will work about half a year in developing novel activatable nanoparticles for brain tumour treatment.  This is a post for a scientist with chemical biology background.

An exciting opportunity has arisen in the Department of Forensic and Neurodevelopmental Sciences in the Institute of Psychiatry, Psychology and Neuroscience for a post-doc to join the world class academic team in neurodevelopmental disorders.  This role will focus on analyses and methods development using MRI (including MRS) from across development to young adulthood. They will contribute to the deliverables of AIMS-2-TRIALS – the world’s largest grant for autism. They will have particular responsibilities for developing methods to analyse brain structure and/or connectivity/and or metabolism from fetal, neonatal, child, adolescent and young adult MRI/MRS data, and its association with neurodevelopmental outcomes including emerging traits linked to autism.

The main part of the job plan (approx. 0.3 FTE) will focus on an NIHR Public Health Research-funded programme (‘HOPEFUL’) which is jointly led by Dr Michelson and Dr Clio Berry (Brighton and Sussex Medical School). Other project partners include Sussex Partnership NHS Foundation Trust, Norfolk and Suffolk NHS Foundation Trust, and the University of Kent. HOPEFUL will undertake a feasibility study and multi-site randomised controlled trial of a hope-focused intervention for young women who are not in education, employment or training, with a geographic focus on deprived coastal regions in southern and eastern England. The Research Clinical Psychologist will work closely with the HOPEFUL team, including academics, senior clinicians and PPI experts, to develop a practice manual, training curricula and supervisory tools for a hope-focused preventive intervention. The post-holder will also be involved in the supervision and training of youth mentors, who will guide the participating young women through the intervention process. The post-holder may also be involved in the direct implementation of the intervention during the feasibility study.

This is an exciting opportunity to join an internationally leading interdisciplinary team in the Department of Women & Children’s Health, King’s College London and work in collaboration with clinical researchers based in our NHS partners (Guy’s and St Thomas’ and King’s College Hospital NHS Foundation Trusts).

Funded by the King’s Health Partner’s Centre for Translational Medicine (CTM), this is a core post to support research generated by research teams within the CTM ‘Conception to Cradle’ programme.  Our research focuses on developing new treatments to tackle infertility and multiomics approaches (including transcriptomics, genomics, metagenomics etc.) to develop new predictors for pregnancy complications.   

The role-holder will play an important role in the on-going development of the KHP Women and Children’s Health Clinical Academic Partnership (WCH CAP). This role combines both leadership in the development and / or operation of a number of critical elements of KHP WCH CAP and the Department of Women and Children’s Health at KCL, with a senior academic fellowship. It is expected that the roleholder will maintain their personal knowledge and skills in clinical epidemiology, and contribute this in areas including WCH research reports, policy consultations, and responses to specialist research and methodology questions through the ‘Ask the Institute’ service .  

This role is for a qualified and experienced Research Scientist who has been working in an academic or commercial research laboratory/ company related to the development, manufacturing and purifiying viral vectors (lenti, retroviral) or other gene therapy products as IMPs. 

The post holder will contribute to the plan to deliver technical innovation and lead specified work packages developing the experimental plan with the Head of Process Development and allocating resources to the tasks within the plan. To ensure successful development and translational of the work to GMP manufacture the candidate requires a strong background/ knowledge of viral vectors and purification methods and excellent interpersonal skills to work within and across diverse teams.

A postdoctoral position is available at King’s College London to work in the groups of Dr. Maria Sanz at KCL and Prof. Franca Fraternali at UCL.

The project involves applying rotational spectroscopy and computational methods, including quantum-chemistry and molecular dynamics calculations, to the investigation of odorants and their interactions with olfactory receptors. 

The project will be developed closely between the Sanz and Fraternali labs and will involve interactions with our industrial partners.

Malware (short for malicious software) refers to any software that perform malicious activities, such as stealing information (e.g., spyware) and damaging systems (e.g., ransomware). Malware authors constantly update their attack strategies to evade detection of antivirus systems, and automatically generate multiple variants of the same malware that are harder to recognize than the original. Traditional malware detection methods relying on manually defined patterns (e.g., sequences of bytes) are time consuming and error prone. Hence, academic and industry researchers have started exploring how Machine Learning (ML) can help in detecting new, unseen malware types.