12 Postdoctoral Fellowship at Saint Louis University, Missouri, USA

The Postdoctoral Fellow will assist the Principal Investigator. The incumbent will conduct research and ensure that all experiments are appropriately conducted following the policies and procedures of Saint Louis University.

The Warren Lab (in the Department of Biology at Saint Louis University is seeking a postdoctoral research associate to join our team seeking to reveal the physiological mechanisms that enable animals to survive severe hypoxia and anoxia. This position is funded by a recent grant from the National Science Foundation (award #2421029) to carry-out studies of neurophysiological function and gene expression in the brain of anoxic turtles. Our lab has recently succeeded in culturing primary neurons from the cerebrocortex of turtles and demonstrated they possess a functional neuronal phenotype. The person hired to fill this position will lead studies of the membrane properties of these isolated neurons in response to anoxia using whole-cell patch-clamp recording techniques.

The Warren Lab is one of many that form part of a vibrant community of neuroscience researchers within Saint Louis University’s Institute for Translational Neuroscience. The St. Louis region is also home to many academic and industrial leaders in the fields of neuroscience and physiology. The position will include travel to conferences and the formation of collaborations with researchers at the University of Toronto and Aarhus University.

Professor Warren is invested in the current and future success of the postdoctoral associate and, with them, will formulate a mentoring plan tailored to their careers upon their arrival. This will include weekly meetings and funding for conference travel.

The Ferris lab at Saint Louis University in St. Louis, MO, is seeking a full-time postdoctoral research associate in the fields of tumor immunology and autoimmunity. We study the dendritic cells required to mount adaptive T cell responses in the context of tumors and autoimmunity to better understand tumor evolution and identify novel therapeutic strategies that can improve patient outcomes. The successful candidate will be highly motivated and intellectually invested. They will have the opportunity pursue their own ideas that are relevant to the overall goals of the lab and drive their own research projects.

Dr. Ferris is an Assistant Professor in the Department of Molecular Microbiology and Immunology. MMI houses a diverse variety of research groups studying virology and innate and adaptive immune responses in the context of viral infection, cancer, and autoimmunity. MMI is a highly collaborative community, meaning the successful candidate will have the opportunity to form relationships with many different laboratory groups and faculty members.

NIH funded postdoctoral positions are available to study the structural enzymology of proteins responsible for blood coagulation (https://biochem.slu.edu/faculty/dicerawp/) with the goal of unraveling the molecular architecture and mechanism of the underlying interactions. The approach uses a combination of conventional (rapid kinetics, protein engineering, X-ray crystallography) and innovative (smFRET, cryo-EM) biophysical techniques. Current projects in the lab focus on the interaction of prothrombin with prothrombinase, leading to generation of thrombin and blood clotting, the activation of factor V required for assembly of prothrombinase and the interaction of the thrombin-thrombomodulin complex with protein C that halts the coagulation response.

Postdoctoral Position in Ion Channels and Membrane Proteins at Saint Louis University

A postdoctoral position is available in the lab of Dr. Gucan Dai at the Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine. We are seeking highly motivated candidates with a strong background in biophysics and biochemistry, particularly in the study of ion channels or membrane proteins. Expertise in patch-clamp electrophysiology or fluorescence imaging is highly desirable.

The Dai lab investigates the fundamental mechanisms of ion channels in excitable membranes using a multidisciplinary approach. Our NIH-funded research integrates structural biology, chemical biology, genetics, fluorescence microscopy, and electrophysiology. The lab is equipped with two cutting-edge patch-clamp electrophysiology/fluorescence imaging systems, including Missouri’s only frequency-domain fluorescence lifetime imaging microscopy system. Research Focus Areas:Voltage-sensing mechanisms of voltage-gated ion channels –These channels are key players in conditions such as chronic pain, cardiac arrhythmias, and epileptic seizures. Trainees will gain hands-on experience with advanced techniques like patch-clamp fluorometry (PCF), Förster resonance energy transfer (FRET), and the use of fluorescent noncanonical amino acids (ncAAs).Lipid-mediated regulation of ion channels and membrane dynamics –This research explores the role of lipids in the regulation of ion channels, with implications for inflammatory and neuropathic pain, Alzheimer’s disease, epilepsy, and viral infections. Relevant techniques include whole-cell fluorometry, calcium imaging, TIRF microscopy, and fluorescence lifetime imaging.

The laboratory of Dr. Liu at the Department of Biology, Saint Louis University, St. Louis, MO, USA, seeks a highly motivated postdoctoral researcher associate to study the structure and function of proteins involved in photophysics and photochemistry in both oxygenic photosynthesis, such as cyanobacteria and
higher plants as well as anoxygenic photosynthesis (green sulfur bacteria, GSB).

Candidates with training in molecular biology and structural biology are encouraged to apply. Experience with protein expression and protein purification/isolation are required. Bioinformatics and structural modelling are also desirable. Additional qualifications include effective writing and communication, strong
problem solving and critical thinking, and ability to work both independently and collaboratively within a multidisciplinary and interactive research environment.

Postdoc in Network Management and Localization at Saint Louis University

Saint Louis University, a Catholic, Jesuit institution dedicated to student learning, research, health care, and service, is seeking applicants for a postdoctoral position in collaboration with the University of Illinois at Urbana-Champaign (UIUC).

The initial appointment is for one year and can be renewed for the second year contingent upon funding availability and satisfactory performance evaluation. The postdoc candidate is expected to catalyze collaborations among the PIs and will be jointly supervised by Drs. Flavio Esposito, Wei Wang, Nan Cen (Computer Science at Saint Louis University), and Dr. Klara Nahrstedt – Professor and Chair of Computer Science at the University of Illinois at Urbana-Champaign (UIUC).

A postdoctoral scientist position available at Saint Louis University to study the connections between lipid load, mitochondrial biology, and cardiac arrhythmias in animal models of cardiomyopathy and heart failure. The position entails working with C. elegans, in addition to ongoing funded studies of inter-generational cardiovascular effects of Nicotine exposure in mice. The lab is also open to topics of mutual interest, as they relate to heart failure and/or cardiovascular toxicity of tobacco products in youth.

A postdoctoral position is available immediately in the laboratory of Dr. Amina Mohammadalipour at Saint Louis University, St. Louis, MO. Alipour lab combines biophysics, mechanobiology, structural biology, membrane proteins, and genetics to understand the fundamental mechanisms underlying cancer cells’ rheological properties.

Past experiences with cell culture, flow cytometry, fluorescence microscopy, and live imaging are required. Experiences in micropipette aspiration, AFM, flow chambers/microfluidic devices, Western blotting, and PCR are preferred but not required.

Applicants should apply through the Saint Louis University website or directly contact Dr. Alipour at [email protected], submitting a single PDF consisting of a cover letter, a CV, and the contact information of two references. Review of applications will begin immediately and continue until the position is filled.

The Laryngeal Biology Laboratory at Saint Louis University, directed by Bernard Rousseau, Ph.D., MMHC, CCC-SLP, ASHA Fellow, Dean of the Doisy College of Health Sciences is recruiting for a Postdoctoral Research Fellow to perform research on an extramurally funded National Institutes of Health R01 project. The Postdoctoral Research Fellow will ensure that all experiments are appropriately conducted following all regulatory policies and procedures.  

The Post Doc Researcher will participate in the generation and analysis of quantitative maps of transcription start sites for a large number of fungal species. This includes CAGE sequencing library preparation and sequencing data analysis, molecular genetic analysis, etc.