13 Postdoctoral Fellowship at University of Leeds, West Yorkshire, England

Are you interested in developing interpretable AI models for the next generation of green syntheses? Do you have experience in AI/Machine Learning, or computational modelling of organic reactions? Do you want to work in a highly interdisciplinary, at the heart of one of the UK’s leading research-intensive universities?

The switch from traditional organic solvents, many of which are hazardous, volatile or non-sustainable, to modern green solvents is one of the key sustainability objectives in High Value Chemical Manufacture. Currently, the use of green solvents is often explored at process development stage, instead of discovery stage, leading to re-optimisation, longer development time, cost, and additional uncertainty. On the other hand, selecting the right solvent early may enhance chemoselectivity, avoid additional reaction steps, and simplify purification of the products.

Do you hold a PhD in Astrophysics or a closely related discipline? Do you have expertise in modelling astrophysical fluid flows or magnetohydrodynamics or accretion disc physics? Do you want to further your career in one of the UKs leading research-intensive Universities?

The University of Leeds invites applications for a Research Fellow position in theoretical and computational astrophysics, funded by a Research Project Grant from the Leverhulme Trust to work with Dr Chris Nixon. This project is a collaboration with Jim Pringle (University of Cambridge) and Tim Naylor (University of Exeter). You will conduct original research into the dynamics of accretion discs, working both independently and in collaboration with project team members. This project seeks to advance our understanding of accretion dynamics through complementary observational and theoretical modelling of accretion discs.

The research project, Inclusive Art for Wicked Problems, is funded by UKRI via a Future Leader Fellowship and will be delivered in collaboration with inclusive arts organisation Pyramid. It will use an arts-based systemic action research methodology to mobilise the expertise and creativity of learning disabled and neurodiverse artists across societal challenges, like care, support, and education. This includes a methodological work package to generate new ways of working that bridges inclusive arts practice and systemic action research, an international collaboration between the UK team and a researcher and art museum professionals in Brazil, and a locally embedded systemic action research project led by Pyramid artists across the Leeds City Region tackling the urgencies and issues with affect them.

Are you an early career researcher looking for an opportunity to take a leading role in health services research to promote patient safety? Do you want to develop your career in one of the UK’s leading research-intensive Universities?

We are looking for an enthusiastic Research Fellow/Officer to work on an NHS Blood and Transplant funded project for 12-months based at the University of Leeds starting in January 2025. The focus of the work is haemovigilance (safety of blood transfusion processes). Working closely with the Serious Hazards of Transfusion (SHOT) program and an international network of research collaborators, the researcher will play an integral role in developing guidance for future haemovigilance systems based on systematic review of research evidence, synthesis of expert subject-matter knowledge and collaborative work with existing systems. Working with the NIHR Patient Safety Research Collaboration at the University of Leeds and the NIHR Blood and Transplant Research Unit in Data Driven Transfusion Practice at the University of Oxford, the work will draw upon Safety Science and Implementation Science to maximise learning from adverse event monitoring and implementation of recommendations from haemovigilance to enhance blood safety.

Are you an ambitious researcher looking for your next challenge? Do you have a background in data analysis, epidemiology and/or statistics? Do you want to further your career in one of the UK’s leading research intensive Universities? 

An exciting opportunity has arisen within the Faculty of Medicine and Health for a highly motivated, enthusiastic individual to join a world-leading clinical research group. 

We are seeking to appoint a talented and able Research Data Analyst to work with the Musculoskeletal Diseases Research Group within the Institute of Rheumatic and Musculoskeletal Medicine. A large part of the post will involve analysis of a 5000 patient longitudinal cohort dataset, analysis of multiple smaller datasets and supporting preparation of peer-reviewed manuscripts.

Are you an early career researcher looking for your first challenge? Do you have a background in Computational Biomechanics? Do you want to further your career in one of the UK’s leading research-intensive universities?

We are looking for a proactive individual to join the Institute of Medical and Biological Engineering to investigate the functional performance in bird skulls through using computational modelling to simulate bone adaptation in the skull.

The role is part of an BBSRC project, in collaboration with the University of Hull, which is investigating how the morphological variation between bird skulls influences their skull biomechanics.

Do you have a background in Data & Computer Science, including Machine Learning? Are you looking to further your career at one of the UK’s leading research-intensive Universities?

We are seeking a highly skilled and innovative data & computer scientist to join our dynamic interdisciplinary team. This role involves collecting, tracking, analysing, and visualising critical data trends related to climate resilience, EPC ratings, clean energy access, house prices, and inequality. The ideal candidate will leverage their robust expertise in data & computer science, software development, machine learning, data analytics, and geospatial technologies to drive the creation of the project’s unique dataset, fundamental to conducting cutting-edge research and data-driven insights, and the development of its interactive web app with advanced data management capabilities that facilitates knowledge dissemination and stakeholder engagement. This includes, supporting research activities, contributing to research results and outputs and to the generation of independent and original ideas, ensuring a successful programme of investigation.

Are you an ambitious researcher looking for your next challenge? Do you have an established background in native mass spectrometry or HDX-MS? Do you want to further your career in one of the UKs leading research intensive Universities?

In this project, funded by a BBSRC Pioneer award, you will develop new mass spectrometry tools based on native MS and hydrogen/deuterium exchange (HDX) to elucidate structure-function relationships of oligonucleotides (OGN). Short DNA and RNA sequences can provide interaction motifs for proteins and antibody-like high-affinity binding (aptamers), but they can also be dynamic and partly unstructured. Recently there has been a surge of interest in OGNs and their derivatives for potential use as drugs and vaccines, but also as targets of pharmaceutical intervention. Currently our insights and toolkit are limited: many sequences are either too small for cryo-EM or too dynamic to easily yield x-ray structures.

Are you an ambitious researcher looking for your next challenge? Do you have an established background in cancer biology, cancer virology or radiobiology? Are you keen to develop new skills in a range of approaches? Do you thrive, working across disciplines with discovery and clinical researchers? Do you want to further your career in one of the UKs leading research intensive Universities?
Applications are invited for a CRUK-funded research fellow position, to understand the mechanisms by which the human papillomavirus (HPV) causes anal cancer. This exciting, timely and transformative research project has the potential to change clinical practice in how we treat these debilitating cancers. Together, we will characterise the key cellular factors underpinning the response to radiotherapy in these cancers to identify novel factors for therapeutic intervention. This research project is a collaboration between experts in HPV (Macdonald) and radiotherapy (Sebag-Montefiore, Samson), combining biochemical, genomic and virological approaches to tackle an important outstanding clinical question on the role of HPV infection on the response to therapy. HPV infection is responsible for ~90% of anal squamous cell carcinomas (ASCC) and virus infection is typically indicative of a positive prognosis in contrast to HPV negative ASCC; however, despite this, most patients that do not respond to radiotherapy are HPV positive. Therefore, it is crucial to uncover the molecular mechanisms of radiotherapy resistance to develop smarter, kinder treatments for these cancers. We have already obtained biopsies from patients that have responded to treatment compared with those who have since relapsed or never responded and will perform RNA-sequencing to look for distinct transcriptional profiles. Therefore, this is an active project that requires someone to drive it forward. You will join a vibrant research community within the Faculty of Biological Sciences at Leeds, including LeedsOmics and the Astbury Centre for Structural Molecular Biology.

Are you an ambitious researcher looking for your next challenge? Do you have a background in Computer Vision / AI? Do you want to further your career in one of the UK’s leading research intensive Universities?

Applications are invited for a full-time Research Fellow to join the tREMOr and ENSURE-AI projects. tREMOr is a timely project that will process videos taken from smartphones to measure key biomarkers for patients suffering from hand tremor. The ultimate aim is to create and evaluate software that will be used in clinical practice to diagnose and monitor patients with movement disorders. A brief description of preliminary work on this project can be found at: https://youtu.be/5lU2yRsma1k. [JE1] [DW2] ENSURE-AI is a flagship project of the National Pathology Imaging Co-operative (NPIC), in which we aim to ensure open and fair assessment of common pathology AI tools.

This role will be based on the university campus, with scope for it to be undertaken in a hybrid manner. We are also open to discussing flexible working arrangements.

Do your research interests concern ethnobotany and its role in climate resilient livelihoods for agro-pastoralist communities? Are you skilled in qualitative and mixed methods research? Have you experience working in interdisciplinary teams? Have you got experience in Ethiopia?

We are seeking a Research Fellow to fulfil a key role in a new grant-funded project “Biodiversity potential for resilient livelihoods in the Lower Omo, Ethiopia”. BioRes is new project studying biodiversity’s role in climate resilience for communities living in the newly-formed Tama Community Conservation Area (CCA), South Omo zone of the Southern Nations, Nationalities and Peoples’ Region (SNNPR), Ethiopia. Over the next three years, BioRes will explore plant and mammal biodiversity, the values of this biodiversity for local communities, and its role in resilient livelihoods, under both current and future climate conditions, to inform the CCA’s regulations.