University of Dundee, Scotland, United Kingdom invites online Application for number of Fully Funded PhD Degree at various Departments. We are providing a list of Fully Funded PhD Programs available at University of Dundee, Scotland, United Kingdom.
Eligible candidate may Apply as soon as possible.
(01) PhD Degree – Fully Funded
PhD position summary/title: Defining airway dysfunction in asthma and COPD using oscillometry towards precision medicine
Chronic airway diseases, including asthma and chronic obstructive pulmonary disease (COPD), are leading causes of morbidity and healthcare utilisation worldwide. Despite advances in therapeutics, substantial heterogeneity remains in disease presentation, progression, and treatment response. Current clinical assessment relies heavily on spirometry, which predominantly reflects large airway function and may fail to detect early or clinically relevant small airways dysfunction (SAD). This limitation contributes to suboptimal phenotyping, delayed intervention, and imprecise risk stratification.
Oscillometry is a non-invasive, tidal breathing technique that provides a detailed assessment of airway resistance and reactance across the bronchial tree, including the small airways. Emerging evidence suggests that oscillometry-defined SAD is highly prevalent in both asthma and COPD and is associated with increased exacerbation risk, symptom burden, and poor disease control. Furthermore, oscillometric indices may capture pathophysiological changes not detectable by spirometry, offering a unique opportunity to refine disease phenotyping and enable precision medicine approaches.
This PhD project will leverage existing well-characterised clinical cohorts and registry infrastructure to investigate the role of oscillometry in asthma and COPD. The overarching aim is to determine whether oscillometry-derived parameters can improve disease phenotyping, predict clinically meaningful outcomes (including exacerbations and remission), and inform treatment response.
Deadline : 3 August 2026
(02) PhD Degree – Fully Funded
PhD position summary/title: Tug-of-War: Dissecting the BACH1-NRF2 axis in lung cancer
Lung cancer remains one of the leading causes of cancer-related death worldwide, highlighting an urgent need for more effective and targeted treatment strategies. Among the molecular pathways implicated in lung tumour progression, two proteins, NRF2 and BACH1, have emerged as key players. Both are frequently elevated in lung tumours, and high levels of either protein are associated with poor patient outcomes. However, despite their importance, their relationship is poorly understood. Intriguingly, NRF2 and BACH1 often exert opposing biological functions, yet they are commonly co-activated in cancer cells, creating a complex regulatory “tug-of-war” that influences tumour behaviour.
This project aims to resolve this paradox by systematically investigating how NRF2 and BACH1 interact and jointly control lung cancer progression. The central goal of this PhD project is to generate a comprehensive and mechanistic understanding of the NRF2-BACH1 axis in lung cancer. To achieve this, the student will employ a combination of cutting-edge genome engineering, functional genomics, and pharmacological approaches. A key component of the project involves the use of a state-of-the-art CRISPR-based system.
Deadline : 30 July 2026
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(03) PhD Degree – Fully Funded
PhD position summary/title: Deciphering the role of UBE2Q1 and non-canonical ubiquitylation in tumorigenesis
Ubiquitylation is a central Post-Translational Modification (PTM) that regulates protein stability, signalling, and many core aspects of cell biology. Classically, ubiquitin is attached to lysine residues on target proteins via isopeptide bonds. However, it is now clear that this view is incomplete. Ubiquitin can also be linked to alternative amino acids, including serine and threonine (via ester bond), and in some contexts to non-protein substrates such as carbohydrates and nucleic acids.
This expanded, “non-canonical” ubiquitylation challenges the traditional framework of ubiquitin biology and points to a much greater chemical and functional diversity than previously appreciated. It suggests that cells have additional, largely unexplored mechanisms to control protein function and signalling dynamics. Understanding these pathways offers new opportunities to uncover how cellular pathway operate under normal conditions and how their disruption contributes to disease.
This PhD project will investigate how non-canonical ubiquitylation contributes to cancer. It focuses on the ubiquitin-conjugating enzyme UBE2Q1, a recently identified mediator of non-canonical ubiquitylation that is often upregulated in aggressive tumours and associated with poor clinical outcomes. By defining the cellular targets and functions of UBE2Q1-driven ubiquitylation, the project aims to uncover previously unrecognised disease mechanisms and identify new opportunities for biomarker development and targeted therapies.
Deadline : 10 June 2026
About The University of Dundee, Scotland, United Kingdom – Official Website
The University of Dundee[a] is a public research university based in Dundee, Scotland. It was founded as a university college in 1881 with a donation from the prominent Baxter family of textile manufacturers. The institution was, for most of its early existence, a constituent college of the University of St Andrews alongside United College and St Mary’s College located in the town of St Andrews itself. Following significant expansion, the University of Dundee gained independent university status by royal charter in 1967 while retaining elements of its ancient heritage and governance structure.
The main campus of the university is located in Dundee’s West End, which contains many of the university’s teaching and research facilities; the Duncan of Jordanstone College of Art and Design, Dundee Law School and the Dundee Dental Hospital and School. The university has additional facilities at Ninewells Hospital, containing its School of Medicine; Perth Royal Infirmary, which houses a clinical research centre; and in Kirkcaldy, Fife, containing part of its School of Health Sciences. The annual income of the institution for 2022–23 was £325.7 million of which £78.9 million was from research grants and contracts, with an expenditure of £330.2 million.
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