Vacancy Edu

05 Postdoctoral Fellowship at Duke University, North Carolina, United States

Duke University, North Carolina, United States invites online Application for various Postdoctoral Fellowship in their different Departments. We are providing a list of Postdoc Fellowship positions available at Duke University, North Carolina, United States.

Eligible candidate may Apply as soon as possible.

 

(01) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral Associates – Cancer Biology, Duke Pathology

 Postdoctoral positions are immediately available in the laboratory of Dr. Ming Chen in the Department of Pathology at the Duke Cancer Institute and Duke University School of Medicine. We are seeking postdoctoral researchers interested in the study of metastasis, PTEN biology, and immunotherapies. Research in the Chen lab is focused on understanding the molecular and genetic events that contribute to cancer progression and metastasis (Lee et al., Science364(6441), 2019; Chen et al., Precis Clin Med 2:183, 2019; Chen et al., J Clin Invest 129:215, 2019; Chen et al., Nat Genet 50:206, 2018). Using a combination of mouse genetics, omics technologies, cross-species analyses, and in vitro approaches, we aim to identify cancer cell–intrinsic and –extrinsic mechanisms driving the aggressiveness of cancer, with a long–term goal of developing therapeutic strategies for preventing and treating human cancer.

Deadline : August 31, 2022

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(02) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral Associate – Skeletal Muscle Biology, Organoids, and Regeneration

Postdoctoral position is immediately available in the Bursac lab (http://bursaclab.pratt.duke.edu/) with the focus on use of human induced pluripotent stem cells (hiPSCs) for studies of skeletal muscle biology, disease, and regeneration. Specifically, 3-dimensional human skeletal muscle tissue organoids (“myobundles”) will be made using myogenic progenitors differentiated from hiPSCs or expanded from human muscle biopsies. These skeletal muscle organoids will be designed to contain robust contractile myofibers and a pool of functional muscle stem cells (satellite cells). Methods will be developed to incorporate primary or hiPSC-derived endothelial cell, immune system cells, and/or motoneurons in myobundles to develop more realistic, high-fidelity tissue-engineered models of skeletal muscle. The initial focus in using this improved model will be on understanding how non-muscle cells regulate satellite cell niche and muscle response to injury. Additionally, these 3D culture system will be used to model and study congenital muscle diseases including Duchenne Muscular Dystrophy, Pompe disease, and Dysferlinopathy (LGMD2B) and to test candidate pharmacological and genome editing (CRISPR/Cas9) therapeutics to improve muscle mass and function. Most promising therapeutic candidates will be eventually validated in mouse models of muscle disease and injury in vivo.

Deadline : October 1, 2022

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(03) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral Associate-Mowery Lab, Radiation Oncology

The goal of the Mowery Lab (https://radonc.duke.edu/research/mowery-lab-0) is to make discoveries that guide the design of improved treatment strategies for patients with head and neck cancer. We have a particular interest in understanding the molecular underpinnings of radiation resistance in head and neck squamous cell carcinoma and immune dysregulation in the tumor microenvironment. We leverage molecular biology techniques, genetically engineered mouse models, and patient-derived tissue specimens to conduct our research. The Mowery Laboratory is based in the Department of Radiation Oncology, and our team works closely with faculty and staff in the Department of Head and Neck Surgery & Communication Sciences, the Department of Radiology, the Department of Pathology, and the Duke Cancer Institute. 

Deadline : July 31, 2022

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(04) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral Associate, Pharmacology and Cancer Biology

The McDonnell laboratory has immediate openings for two Postdoctoral Fellows to study the molecular pharmacology of the androgen and estrogen receptors and their signaling pathways in cancer and other endocrine disorders. Candidates interested in hormone action, signaling, drug action and contemporary drug discovery are encouraged to apply as are those interested in defining how sex hormones impact tumor immunity. The group maintains close collaborative relationships with several pharmaceutical companies and thus trainees have the opportunity to engage in research activities/projects that will prepare them for careers in industry or academics.  Candidates with a background in molecular biology, pharmacology or medicinal chemistry are encouraged to apply. 

Deadline : July 31, 2022

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(05) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: POSTDOCTORAL ASSOCIATE

Dr. Sudha Shenoy’s laboratory is seeking a recent PhD graduate interested in the study of signaling and trafficking of seven-transmembrane/G-protein-coupled receptors (7TMR/GPCRs). 7TMRs/GPCRs are the largest and most diverse class of signaling receptors in the mammalian genome and the target of nearly half the drugs currently in use. We are interested in the regulation of 7TMRs by deubiquitinases, especially in the context of cardiomyocyte death during chronic pressure overload.  Candidate who is highly motivated and shares a vision of excellence and commitment to research with a recent PhD in Pharmacology, Cell Biology or related discipline is preferred. Prior experience with mouse models is also preferred.

Deadline : August 31, 2022

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About Duke University, North Carolina, USA – Official Website

Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day town of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James Buchanan Duke established The Duke Endowment and the institution changed its name to honor his deceased father, Washington Duke.

Duke’s campus spans over 8,600 acres (3,500 hectares) on three contiguous sub-campuses in Durham as well as a marine lab in Beaufort. The West Campus—designed largely by architect Julian Abele, an African American architect who graduated first in his class at University of Pennsylvania School of Design—incorporates Gothic architecture with the 210-foot (64-meter) Duke Chapel at the campus’ center and highest point of elevation, is adjacent to the Medical Center. East Campus, 1.5 miles (2.4 kilometers) away, home to all first-years, contains Georgian-style architecture.The university administers two concurrent schools in Asia, Duke-NUS Medical School in Singapore (established in 2005) and Duke Kunshan University in Kunshan, China (established in 2013).

Duke University is ranked among the top universities in the United States. Undergraduate admissions are among the most selective in the country. It spends more money conducting research than most other universities in the country and its researchers are among the most frequently cited. As of 2019, 15 Nobel laureates and 3 Turing Award winners have been affiliated with the university. Duke alumni also include 50 Rhodes Scholars, 25 Churchill Scholars, 13 Schwarzman Scholars, and 8 Mitchell Scholars. The university has produced the third highest number of Churchill Scholars of any university (behind Princeton and Harvard) and the fifth-highest number of Rhodes, Marshall, Truman, Goldwater, and Udall Scholars of any American university between 1986 and 2015. Duke is the alma mater of one president of the United States (Richard Nixon) and 14 living billionaires.

 

 

 

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