23 Postdoctoral Fellowship at Ohio State University, United States

The Science and Dissemination Lead will report to the Director of Health Services Research and work closely with programmatic leads and data analysts to 1) independently lead projects to successful publication in scientific peer-reviewed journals, 2) ensure that HOPES products (reports, papers, presentations, briefs, etc.) are high quality and add to/enhance existing health services research, 3) critically review HOPES portfolio of projects for scientific merit and coherence, as well as potential limitations, 4) train all HOPES team members on and support them with other strategies for building scientific evidence, including poster and oral presentations at scientific conferences; managing project direction and study design to meet manuscript standards; performing literature reviews and synthesizing information; creating diagrams, tables, and other visuals to summarize data; and managing references and citations, 5) researching opportunities for additional funding and leading a team approach for developing and writing project proposals, and 6) establish regular meetings with academic and non-academic partners/stakeholders to co-develop, validate, and disseminate HOPES scientific products to facilitate uptake and implementation of findings in real-world settings.

Researcher 2 – to assist and support scientific investigation to study human cancer as directed in the Comprehensive Cancer Center; oversees and maintains accurate records of laboratory activities; assists with training of junior research staff, and undergraduate and graduate students in research methods and equipment operation; assists PI and communicate with collaborators and physicians and operate lab; Assist PI with grant preparation, especially administrative documents including Biosketches, facilities, LOS, and communications with HR and grant managers, etc.; assists principal investigator with the preparation of  publications, manuscripts, articles, posters, and abstracts; conducts library research on requested topics through researching current literature; oversees and maintains accurate records of laboratory activities; assists with training of junior research staff, and undergraduate and graduate students in research methods and equipment operation; sets up and operates laboratory equipment; monitors research supply, including specimens, inventory and initiates procurement requests  as needed.

Post Doctoral Scholar to pursue research on skin inflammation in the Department of Microbial Infection & Immunity; designs, conducts, and evaluates research experiments; analyzes and interprets data; performs scientific literature searches; participates in journal clubs, laboratory meetings, and Department seminars and activities; assists with training of other lab members; writes research papers for publication; presents research findings at local, national, or international scientific meetings; applies for postdoctoral fellowships; assists PI with writing and submitting grant proposals to obtain extramural funding in support of research.

The position will entail independently performing directed laboratory research related to the synthesis and study of homogeneous catalysts using novel ligand platforms and earth abundant metals. Additional responsibilities will include training and assisting undergraduate and graduate researchers, assisting with the preparation and submission of manuscripts, and maintaining equipment in the research laboratory.

The Research Scientist in the Rich lab will: interface with and maintain the project-specific “EMERGE Database” and other NSF and NASA funded projects, leading the addition of new datasets into this interactive repository, in close collaboration with diverse project personnel and collaborators; Assist in running sections of EMERGE collaborative groups; designs and executes independent research using molecular microbial & viral datasets, from diverse Arctic locations, to characterize emergent community elements in these dynamically changing systems, and statistically link those observations to paired geochemical datasets; maintains current knowledge of appropriate scientific literature; writes research manuscripts and reviews; attends scientific meetings and presents data; participates in fellowship and grant application writing and submission; field site travel and project workshops.

Researcher 3 to conduct complex scientific investigations in a foundational (basic) research laboratory in the Department of Microbial Infection and Immunity functioning as a specialist or technical expert in immune responses to Leishmania infection; collaborates with Principal Investigator (PI) to develop, manage and implement research projects; plans, designs, and conducts complex & advanced research; plans and executes advanced molecular biological and biochemical procedures specializing & providing technical expertise in cellular biology, molecular biology, and/or flow cytometry; extracts, analyzes & evaluates experimental data; develops and implements new or revised research methods; assists PI in research & development efforts of new research projects; works closely with PI to determine and develop goals of projects; develops and establishes criteria & research standards to meet goals of research projects; plans and writes manuscripts, articles, abstracts and research reports for publication in scientific journals; attends and presents research results at national and international scientific conferences and workshops; actively contributes to developing, writing, editing and critiquing research grant proposals; investigates potential sources of funding and makes recommendations to principal investigators; participates in developing and establishing working relationships with current & potential sponsors of research; oversees appropriate maintenance of all laboratory equipment; negotiates and oversees equipment service contracts and repairs; participates in developing and implementing laboratory Standard Operating Procedures (SOPs) and Safety Manual; monitors, oversees & ensures compliance to local, state and federal laboratory health and safety rules, regulations and guidelines; provides training of research staff in executing new research methods; serves as a consultant to other investigators in area of expertise; participates in journal clubs, laboratory meetings and Department activities.

Dr. Guo’s laboratory focuses on cancer metabolism, signal transduction, autophagy, and miRNA across multiple cancer types, including brain tumors, lung cancer, liver cancer, sarcoma, pancreatic cancer, etc. The research also expands to immune metabolism and collaborates with world-leader in the immune-oncology field. His lab was the first to identify EGFR/PI3K signaling upregulates SREBP-1, a membrane-bound transcription factor with a central role in lipid metabolism to control tumor growth (Guo, et al, PNAS, Science Signaling, 2009, Cancer Discovery 2011, Current Pharma Design 2014). Most recently, his lab further unraveled the underlying molecular mechanism linking EGFR/PI3K signaling and glucose to SREBP-1-regulated lipid metabolism. They found that glucose acting as an indispensable activator promotes SREBP signaling pathway via N-glycosylation modification on SCAP protein (Cheng et al., Cancer Cell, 2015). Moreover, they found lipid droplets and miRNA are actively involved in SREBPs regulation and lipid metabolism in malignancies (Geng, et al., Clinical Cancer Research 2016, and Peng et al., Cell Reports 2016, Xiang, et al., Cell Metabolism 2020).

There is a postdoctoral research position opening in the laboratory of Deliang Guo, PhD, Director of the Center of Cancer Metabolism at The Ohio State University. His laboratory focuses on cancer metabolism, signal transduction, autophagy and miRNA across multiple cancer types, including brain tumors, lung cancer, liver cancer, sarcoma, pancreatic cancer etc. The research also expands to immune-metabolism and collaborate with world-leader in immune-oncology field. His lab was the first to identify EGFR/PI3K signaling upregulates SREBP-1, a membrane-bound transcription factor with a central role in lipid metabolism to control tumor growth (Guo, et al, PNAS, Science Signaling, 2009, Cancer Discovery 2011, Current Pharma Design 2014). Most recently, his lab further unraveled the underlying molecular mechanism linking EGFR/PI3K signaling and glucose to SREBP-1-regulated lipid metabolism. They found that glucose acting as an indispensable activator promotes SREBP signaling pathway via N-glycosylation modification on SCAP protein (Cheng et al., Cancer Cell, 2015). Moreover, they found lipid droplets and miRNA are actively involved in SREBPs regulation and lipid metabolism in malignancies (Geng, et al., Clinical Cancer Research 2016, and Peng et al., Cell Reports 2016, Xiang, et al., Cell Metabolism 2020).

The Departments of Physics, within the College of Arts and Sciences, seek a Post Doctoral Scholar. The successful candidate will be expected to play a leading role in both the High Luminosity (HL-LHC) upgrade of the CMS detector and the analysis of Run 3 data when the LHC resumes operation next year. Successful applicants will strengthen the existing efforts of the OSU CMS group in these areas. In particular, for the HL-LHC this hire will join either the Forward Pixel Tracker (TFPX) Silicon Pixel Detector Construction project where OSU is one of the two model testing centers in the US, or the Endcap Muon project where OSU is involved in upgrades to the front-end electronics. For data analysis, the hire will be encouraged to develop innovative searches for Beyond the Standard Model (BSM) physics that complement the group’s existing analyses, where the emphasis for the past decade has been on long-lived particles (LLPs).

Research Associate 2-B/H designs, executes and manages research projects investigating foundational (basic) biological/health science research laboratories in the Department of Psychiatry and Behavioral Health. Collaborates with principal investigator (PI) to develop and implement goals and objectives of studies; conceptualizes, designs and executes complex laboratory experiments; plans, coordinates and oversees processing and analysis of data; analyzes and interprets research data; develops and implements new and/or revised research methodology and techniques; plans and tests experimental designs, sampling techniques, and analytical methods; develops and establishes research controls, criteria and standards; performs critical analysis of literature relevant to research; collaborates with principal investigator to write and prepare research papers and manuscripts for publication and presentation at national and conferences and workshops, and in the writing of project reports, articles and other documents; attends and presents research results at national and international scientific conferences, workshops and seminars; assists with development, writing and preparation of grant proposals to obtain new or renewal of extramural funding in support of research; investigates, identifies and recommends possible sources of research funding; participates in developing and managing grant budgets; monitors expenses; monitors and enforces laboratory safety procedures to ensure compliance with OSHA regulations, as well as local, state and federal regulations, including proper disposal and maintenance of regulated materials; trains and/or supervises research staff; manages daily operations of the laboratory; oversees and initiates procurement of lab supplies and equipment; provides technical assistance and supervision of equipment; negotiates and oversees equipment service contracts and repairs.

A research associate position is available beginning early 2023 to work on complementary research in landscape ecology.  The successful applicant will join a dynamic team to lead complex establishment of a field research project aiming to advance understanding of critical cerulean warbler habitat across forested landscapes of Ohio. Further the successful applicant will actively engage in independent research that aligns in our ongoing efforts to provide additional insights into tree species interactions and their response to climate change This will include leading geospatial analysis to develop and advance understanding of how life history traits can be more fully incorporated into tree species distribution and disturbance models. This project builds on our work on climate change tree and bird atlases (https://www.fs.usda.gov/nrs/atlas/). The unifying theme of the work will hinge on the applicant’s research experience to advance understanding of the importance of how cross scale ecological processes impacting wildlife and forests.  The successful applicant will work closely with the Ohio State University and USDA Forest Service scientists in the Northern Research Station in Delaware, Ohio. The desired start date is January 2023, but a later date may be considered for competitive applicants.

Post Doctoral Scholar to support laboratory work in mucosal immunology, microbiota and allergies. The Postdoc will be expected to conduct research and provide technical assistance to the PI, students, and trainees, as needed. Main roles for the individual hired for this position will include (1) collaborating with the PI in the generation and testing of research hypotheses and data analysis, writing of papers, grants, and reports, and preparation of presentations and lectures; 2) collecting and organizing data for research activities; 3) attending, participating, or presenting at laboratory meetings, seminars, graduate and undergraduate lectures, and conferences as needed; 4) performing miscellaneous office duties as assigned by the PI (s) including, but not limited to, ordering supplies and helping the PI(s) in the organization and coordination of meetings and projects; 5) maintaining frequent communication with colleague lab mates and collaborators . Work hours will typically occur between normal business hours but may occasionally require some evenings, weekends and/or holiday hours.

The Post Doctoral Scholar will study molecular, cellular, and immunological mechanisms that facilitate interkingdom transmission of obligatory intracellular bacteria between mammals and ticks by using knockout mutant bacteria, ticks, mouse, and dogs as animal models. This position will also be tasked to identify and characterize bacterial proteins and cognitive host cell molecules and signaling pathways. The long-term goal is to develop tick transmission blocking vaccines for this group of pathogens. Clone and purify various molecules, ability to culture bacteria in mammalian and tick cells, use advanced microscopy, immunological assays including flow cytometry, handling ticks, mice, and dogs including blood and tissue sample collection, and genotype analysis, and various sterile techniques.

The Center for Retrovirus Research located in the College of Veterinary Medicine, Department of Veterinary Biosciences at The Ohio State University is seeking a Post-Doctoral Researcher or Research Scientist for a new project related to COVID-19 and its associated SARS-CoV-2. The project is particularly focused on host antibody response to SARS-CoV-2 infection. This position is available for one year, with possible renewal beyond depending on funding and performance. The researcher will join an active and productive research lab with a primary focus in virus-host interaction, membrane fusion and entry of enveloped RNA viruses as well as host innate immunity to viral infection. The lab has a strong interest in retroviruses including HIV, influenza A virus, Zika virus, Ebola virus, and innate sensing to RNA viruses. Highly motivated individuals with a strong background in virology, cell biology, and innate immunity are encouraged to apply. The lab is especially seeking candidates who have skills and experience in immunology, cell biology, viral entry, and pathogenesis. Recently graduated PhD candidates are encouraged to apply.

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Post Doctoral Scholar

Deadline : Open Until Filled

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Post Doctoral position in the Department of Neurological Surgery to identify novel therapeutic strategies to provide neuroprotection and improve functional recovery in the post-ischemic brain. In vivo animal models, slice electrophysiology, histological, immunohistochemical analysis of cell death, and neurobehavioral testing are utilized for the interdisciplinary studies performed in our laboratory. This is a unique opportunity to perform slice electrophysiology experiments following translational animal models of brain ischemia (stroke and cardiac arrest) or traumatic brain injury (TBI). The candidate should have a PhD degree in Neuroscience or related field (or MD with research experience) and electrophysiology experience is desired. Dr. Herson has >15 years’ experience performing and supervising electrophysiology and the post-doc will be trained in methods if needed. The position will work in a collaborative team environment, while being expected to be a self-motivated investigator who can manage their time efficiently. The candidate is expected to have strong organizational and record keeping skills to record experiment results and analyze data, as well as effective written communication skills to publish results.

Post-Doctoral Scholar to pursue specialized research training and experience under the guidance of a scientific mentor in a research laboratory within the Department of Psychiatry and Behavioral Health.

• Plans, designs, and executes experiments of considerable scope and complexity in the study of suicide and posttraumatic stress disorder (PTSD).
• Collects and analyzes data for research sponsored by the National Institute of Health (NIH) and the Department of Defense (DOD).
• Performs analysis of data and prepares results of research for publication.
• Actively participates in the recruitment and interview of prospective study participants.
• Creates stimulus materials and performs testing of human subjects.
• Assists PI with grant proposals to obtain outside funding from state and federal agencies.
• Develops, adopts and implements new laboratory methods.

The Post Doctoral Scholar will pursue specialized research training and experience in the laboratory of Dr. Andreas Wieland (Principal Investigator) in the Department of Otolaryngology (part of the newly created Pelotonia Institute for Immuno-Oncology (PIIO) within the Comprehensive Cancer Center at the Ohio State University. The research in the Wieland lab is aimed at gaining a better understanding of the immunological landscape of tumors, with an emphasis on human papillomavirus (HPV)-positive head and neck cancer (PMIDs: 33208941, 34471285).

Post Doctoral position in the Department of Neurological Surgery to identify novel therapeutic strategies to provide neuroprotection and improve functional recovery in the post-ischemic brain. In vivo animal models, slice electrophysiology, histological, immunohistochemical analysis of cell death, and neurobehavioral testing are utilized for the interdisciplinary studies performed in our laboratory. This is a unique opportunity to perform slice electrophysiology experiments following translational animal models of brain ischemia (stroke and cardiac arrest) or traumatic brain injury (TBI). The candidate should have a PhD degree in Neuroscience or related field (or MD with research experience) and electrophysiology experience is desired. Dr. Herson has >15 years’ experience performing and supervising electrophysiology and the post-doc will be trained in methods if needed. The position will work in a collaborative team environment, while being expected to be a self-motivated investigator who can manage their time efficiently. The candidate is expected to have strong organizational and record keeping skills to record experiment results and analyze data, as well as effective written communication skills to publish results.

The Townsend Lab has an immediate opening for a basic/translational postdoctoral scholar with experience and interest in investigating adult brain plasticity and stem cells. This funded project will investigate hypothalamic tanycytes, adult stem cells marked by telomerase reverse transcriptase, and how adult neural plasticity and remodeling impacts the regulation of energy balance (appetite, neuroendocrine function, sympathetic outflow to adipose, etc.). This project is partially funded by NSF, and will also partially be funded by NIH, spanning the basic to translational spectrum using both mouse and human brain samples. Experience with mouse husbandry and transgenic strains, stereotaxic surgery, brain anatomy, immunofluorescence and confocal microscopy, and molecular biology techniques are strongly preferred.

Candidates should be highly motivated, independent, headed for an independent research career, passionate about team/collaborative science, mentoring in the lab, honesty and integrity, fostering a dynamic and functional lab environment, and maintaining an organized, rigorous and well-documented research program. The Townsend Lab believes strongly in supportive mentoring, career advancement, professional development, and collegiality.