24 Postdoctoral Fellowship at King’s College London, United Kingdom

We are seeking a Deputy Director to assist in managing the Preclinical Neuroimaging and Biomarkers Facility at Denmark Hill. This role supports the Director in overseeing daily operations and strategic development, with the goal of establishing a globally recognized centre for neuroscience research.

The successful candidate will collaborate with the Director in strategic and operational planning to enhance research capabilities. They will oversee project coordination, facilitating the provision of imaging and complementary methodologies from inception through to publication. This includes managing protocol meetings, evaluating new projects, and providing cost evaluations and feedback to researchers.

The department of Informatics is looking to appoint a post-doctoral researcher to work in the area of cryptography. 

The postdoc will work alongside Prof. Martin Albrecht and other cryptographic researchers in the department on topics in lattice-based cryptography and related fields. The post is funded by an ERC/UKRI Frontier Research grant on investigating practical advanced post-quantum cryptography from lattices. 

The applicant will work in the cryptography lab in the Cybersecurity group (CYS) in the department. The cryptography lab currently consists of Martin Albrecht, Ngoc Khanh Nguyen, Eamonn Postlethwaite and Yixin Shen. The mission of the cryptography lab is to conduct word-class research to address research and practical challenges in cryptography. 

You will be an individual with clinical experience in maternity care and extensive research experience, who will support a research project evaluating the implementation of the Tommy’s National Centre for Maternity Improvement’s Clinical Decision Support Tool as part of the NIHR funded PARTNER cluster randomised controlled trial.  This follows an implementation evaluation of the Tool in four early adopter NHS Trusts (ISRCTN13498237).  The Tommy’s National Centre for Maternity Improvement is a collaboration between the Royal College of Obstetricians and Gynaecologists (RCOG), Royal College of Midwives (RCM), the research and information charity, Tommy’s, King’s College London, Universities of Bristol and Sheffield, St George’s University of London, and the PROMPT Maternity Foundation charity. The Tommy’s Clinical Decision Support Tool was developed by the Centre to more accurately predict risk of preterm birth and placental disorders that can lead to preeclampsia, fetal growth restriction and stillbirth.

KiTEC is looking for a Senior Health Technology Assessor (HTA) to join the health technology assessment team. KiTEC conducts independent evaluations of medical devices, digital and AI health technologies for NICE and the NHS and helps start-ups and SMEs to develop and provide evidentiary support for their value proposition. This includes writing grant applications to secure funding.

The successful candidate will work closely with the director to manage the delivery of health technology assessment projects and undertake business development and client relationship activities in support of these activities, particularly in the area of AI enabled devices. This person would also be expected to contribute and lead initiatives to support KiTEC’s strategic direction. A working knowledge of systems thinking in healthcare and experience of thought leadership initiatives would be advantageous in this role. Contributions to research projects within the school are also supported should the successful candidate wish to pursue an academic career.

This is an exciting opportunity to be part of a new Wellcome Trust funded Discovery Award to examine prediction of clinical outcome. A key psychological mechanism that maintains anxiety is the tendency to generate negative interpretations of unclear or ambiguous information (known as interpretation bias). We have developed a novel online intervention using cognitive bias modification of interpretations (CBM-I) to ‘train’ people with anxiety problems to develop a more helpful cognitive bias to generate positive interpretations, which effectively reduces anxiety and depression. This low-intensity intervention is straightforward, accessible and can be offered at scale. In the current project we will use cognitive, genetic, clinical and demographic information to predict clinical outcome at the end of the CBM-I intervention and at follow up. This is something people with lived of anxiety have told us that they would like, to help inform their decisions selecting a treatment option. 

We are recruiting a highly motivated postdoctoral geneticist to join a collaborative initiative between King’s College London and leading industry partner. This programme aims to identify and validate potential targets for treatments for Motor Neurone Disease (MND) through comprehensive genomic research. By analysing large-scale genetics datasets, our objective is to identify and validate potential therapeutic targets and study their underlying mechanisms to accelerate the development of effective MND treatments. The successful candidate will join a team of neuroscientists and computational experts at the King’s MND Care and Research Centre, where they will have a leading role in developing computational analysis methods and analysing large-scale multi-omics datasets comprising thousands of samples. The post will be based within Dr Ahmad Al Khleifat Personalised Medicine team at the Department Clinical Neuroscience also working closely with Dr Alfredo Iacoangeli at the Biostatistics and Health Informatics.

We are seeking a highly motivated and conscientious post-doctoral researcher to join a very collaborative, interdisciplinary, and friendly research group at King’s College London led by Professor Bipin Rajendran. 

The group at King’s is part of a consortium developing multiprocessor systems-on-chip with advanced nanoscale in-memory neural processing units that are funded by the Horizon Europe Programme. The consortium team will develop an advanced Multi-Processor System on Chip prototype in FD-SOI 28nm CMOS technology that tightly integrates an Analog In-Memory Computing (AIMC) unit based on embedded phase-change memory technology. As part of this project, you will have the opportunity to collaborate with world-leading researchers from industries (including IBM Research and ST Microelectronics) and universities in Europe.

We are looking for an enthusiastic postgraduate with a PhD in psychology or behavioural genetics, and particular interest in anxiety and/or depression.

The sucessful applicant will work as a Postdoctoral Research Associate with Prof Thalia Eley in the Social, Genetic and Developmental Psychiatry (SGDP) Centre. They will be a member of her Emotional Development, Intervention and Treatment (EDIT) Lab, which strives to be a diverse research environment that is open, welcoming and supportive to all.

If successful, you will work with data from the Twins Early Development Study (TEDS). The TEDS team have followed thousands of twin pairs since birth, tracking their emotional, cognitive and behavioural development. We have recently completed a  major mental health assessment  as the twins reach their late twenties. We are also engaged in a challenging new effort linking the twins’ medical records to the information we already hold on them. You will lead analyses of the data resulting from these activities.

Applications are invited for a postdoctoral research associate position in Dr. Angika Basant’s group at the Randall Centre for Cell and Molecular Biophysics, King’s College London.  

The Basant group, funded by a grant from the Wellcome Trust, seeks to understand how tyrosine phosphatases regulate cell signalling. This large family of enzymes has been highly understudied compared to its kinase counterpart. We investigate these phosphatases in the context of signalling to the actin cytoskeleton and in virus-infected cells.

The researcher appointed will focus on candidate phosphatases that have been validated to regulate actin dynamics during infection with the poxvirus Vaccinia. How do these phosphatases function, what are their key interactors, how do they recognise substrates, how do they impact signalling dynamics and outputs? The broader goal is to contextualise these findings in uninfected cells and, with the help of a collaborator, in other viral infections. The researcher appointed will take advantage of, and further develop, a Vaccinia virus-based signalling platform, as well as cutting-edge molecule counting and optogenetics tools available in the lab. Experience in phosphatase biology, microscopy, cell signalling or biochemistry is desirable but not mandatory.

We are seeking a highly motivated and experienced researcher, holding a PhD in biophysics, biochemistry  or related disciplines that has experience and is interested in different aspects of single molecule mechanobiology. The candidate will work with single molecule AFM and magnetic tweezers to study the nanomechanical properties of cell-cell junction proteins.

The project is funded by a BBSRC sLOLA programme. The project will be developed between the Francis Crick Institute and the Department of Physics at King’s College London.

We are seeking to appoint a biophysicist or a cell/molecular biologist (preferably with a PhD in Physics, Cell/Molecular Biology, Chemistry, Biochemistry, Bioengineering or related disciplines) with proved experience in any area of mechanobiology.

This project aims to investigate the molecular mechanisms by which extracellular mechanical forces travel long distances inside the cell to reach the nucleus on biologically-relevant timescales, and how mechanical forces activate force-induced transcriptional programmes. The project can be attacked from different perspectives (single molecule, single cell, or tissue level) but in all cases requires extensive experience in the relevant mechanical techniques, according to each relevant length-scale. The project is funded by the Wellcome Trust. The project will be developed between the Francis Crick Institute and the Department of Physics at King’s College London.

The laboratory of Dr Ryuichi Fukuda at King’s College London British Heart Foundation (BHF) Centre of Research Excellence is looking for a postdoctoral researcher with a unique and very good personality. This role is to conduct research independently, analyses data and present results. Your work will be carried out under the supervision of Dr Fukuda and to study cardiac development and disease using multiple model systems.

The lab is interested in broader areas of cardiac biology using organoids from human pluripotent stem cells, mice and zebrafish. This project focuses on the study of mechanisms that regulate cardiac differentiation and disease. Ideal candidates should have excellent skills in human pluripotent stem cell culture or mouse genetics/surgery, such as MI and TAC, as well as techniques such as CRISPR/Cas9 genome editing, live cell imaging and plasmid design/cloning.

Post-doctoral Research Associate in the Department of Diabetes at King’s College London in the laboratory of Dr. Aileen King. The project will focus on understanding sex differences in a mouse model of beta cell endoplasmic reticulum stress. The post holder will use a wide range of in vitro and in vivo techniques including small animal surgery. The candidate should either have prior experience of rodent islet isolation and functional assessment of islets OR should have experience in small animal surgery. They should also have expertise in molecular cell biology techniques such as western blotting and immunohistochemistry.

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral Research Associate at the Social, Genetic & Developmental Psychiatry Centre

Deadline : 08 July 2024.

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We are looking for a skilled postdoctoral researcher with a strong background in molecular biology, cell biology, genetics or development. The project will investigate the role of transposable elements in pregnancy complications. The postholder will combine genome-wide genetic and epigenetic analyses of patient samples with functional assays utilising human tissue culture of trophoblast cells and organoids, as well as molecular cloning to generate CRISPR-Cas9 genome editing constructs.

The Nott group is looking for a skilled and motivated Postdoctoral Research Associate with a strong background in structural biology, cell biology, or biophysics. The project will combine novel methods for studying membraneless organelles with structural strategies for characterising molecular conformations, interactions, and enzyme activity.

Applicants should hold (or be near completion of) a PhD in a relevant area of biological or physical science and have the ability to independently drive an interdisciplinary project. Expertise in structural, biophysical, or cellular methods are all advantageous. Applicants should have a keen interest in the biology of membraneless cellular compartments, excellent communication skills, and the ability to write for scientific publication.  

A Research Associate position to research on Brain Cancer Immunotherapy is available for 12 months initially commencing in July 2024 (or soon after) to join a multidisciplinary and a highly collaborative team working on lipid nanoparticle-mediated co-delivery of immunogenic cell death chemotherapeutics and immune checkpoint blockade nucleic acids to treat brain cancer. Applicants will have the opportunity to contribute to other projects linked to brain research as opportunities arise.

Applicants should have a relevant PhD field and preferably post-doctorate experience in one of the following fields: pharmacy, drug delivery, cancer biology, immunology, molecular biology, biochemistry, bioengineering, material/chemical science or any other relevant fields. Holding a Home Office (Scientific Procedures) Act 1986 Licence or equivalent and experience in handling animals is highly desirable.

The postholder will be based in the co-ordinating centre (Institute of Psychiatry, Psychology & Neuroscience, King’s College London) and will be responsible for a) overall co-ordination of the INTREPID III programme, b) supporting and liaising with each participating centre to ensure planned activities are conducted in line with the programme timetable, and c) contributing to collating and analysing material and data generated by the INTREPID III programme. Travel to each site in each of the partner countries will be required.

The post holder will have experience conducting mental health research, excellent knowledge of quantitative and/or qualitative research methods, and excellent knowledge of the social determinants of health. They will have experience of working on interdisciplinary international research projects, experience of working with people with mental health problems, strong organisational skills, and a proven ability to work in diverse teams and liaise with other professionals and academics across cultures.

The role of the PDRA is to support and assist with the data analysis, write up and dissemination of some of the key tasks of the project. This includes the analysis and write up using the TransEuroWorks Survey data particularly on flexibility stigma perceptions of European workers, using an experimental vignette survey set up. The PDRA is also expected to use wide range of secondary data including, but not limited to, the European Working Conditions Survey. European Labour Force Survey, UK and German Household Panel data to examine the well-being outcomes of flexible working arrangements in a cross-national and longitudinal perspective.