26 Postdoctoral Fellowship at University of Manchester, England

The  MOJO and the Soteria projects are UK Research and Innovation funded collaboration between THG plc (THG), the University of Manchester and the University of Oxford. The partnership will develop demonstrations of managed runtime systems using OpenJDK, Graal and Truffle to work with Arm’s prototype Morello SOC, previously awarded UKRI funding. We are working to demonstrate the feasibility and benefits of running e-commerce application software stacks on Morello’s Capability Hardware Enhanced ISA. The Soteria project will demonstrate e-commerce applications benefiting from the enhanced security instruction set of Arm’s Morello microprocessor. The MoatE project is an extension and enhancement of this effort, to deliver an OpenJDK17 based environment with support for advanced Just-in-time compilation (using Graal), support for guest languages such as JavaScript and Python (using Truffle) and modern garbage collector algorithms (such as G1/Shenandoah and research implementations using mmtk). The overall purpose is to investigate how to improve the security of the Hotspot JVM and managed languages in general by taking advantage of the Arm Morello architecture. Thus, the job involves helping to complete the port of Hotspot JVM, Graal, Truffle and modern garbage collection algorithms to the Arm Morello architecture as well as prototyping research ideas, evaluate them and write research papers based on the research. ​​​​​​​

In this project we seek a motivated individual, with extensive mass spectrometry experience, who wants to develop a new instrument and apply it to the study of MDa. protein assemblies. You will be based in the team of Prof. Perdita Barran in the Michael Barber Centre for Collaborative Mass Spectrometry, and work closely with Dr. John Hoyes (TrueMass Ltd.), Dr. Dimitris Papamastasiou (Fasmatech Ltd.) and Prof. Rob Appleby (UoM). Your primary role will be to build, install and test a new geometry CDMS instrument with a novel ESI source with improved characteristics for the transmission of MDa ions The project also involves close collaboration with Prof. Brian Biggar (UoM) and collaborators at Pharmaron ltd. as we apply the technology to determine the DNA content of recombinant adenoassociated viral (AAV) vectors. We propose to compare the capabilities of this instrument with that of commercially available mass spectrometry platforms and other methods. As part of this exciting and truly interdisciplinary project you will also build a stage to allow subsequent characterisation of these MDa. complexes via microscopy.

A Postdoctoral Research Associate Position (PDRA) is available from 1st November 2023 for 24 months with a possible 12 month extension to carry out research for a fully jointly funded cyber-security for UK future sustainable energy network by Scottish Power Energy Network (SPEN) and National Grid (NG). The aims of Cyber-SAFEN project is to investigate suitable methods of essential cyber safe and resilient functions and develop an integrated cyber Intrusion Response Defence System (IRDS) for UK electricity networks Protection Automation Control (PAC) systems, Wide Area Monitoring (WAM) PAC systems and SCADA systems against advanced cyber-attacks, and to accelerate the UK confidently moving to low carbon economy.

The SECCOM project will investigate the art of architectural possibility, a model for security reasoning, and approach to dynamic verification of computer system constructed utilizing composable fabrics such as PCIe and Compute Express Link (CXL). This multi-faceted project is looking to hire a Research Associate or Research Fellow to work with the PI/CoIs on this exciting new area of research. Applications are welcome for a Post-doc to work on the development for a model of security reasoning based on the theory and practice of composition frameworks through cryptographic protocols and hardware. The position is funded as part of the UKRI/EPSRC project “SECCOM: Securing composable Hardware Platforms” with funding from MoD/Dstl.  Offers for the position will therefore be conditional on passing an identity check with Dstl. You will be hosted by Bernardo Magri at the Systems and Software Security group within the Computer Science Department at The University of Manchester, located in the Northwest of England (https://www.cs.manchester.ac.uk/research/expertise/systems-and-software-security/).

The SECCOM project will investigate the art of architectural possibility, a model for security reasoning, and approach to dynamic verification of computer system constructed utilizing composable fabrics such as PCIe and Compute Express Link (CXL). This multi-faceted project is looking to hire a Research Associate or Research Fellow to work with the PI/CoIs on this exciting new area of research. Applications are welcome for a Post-doc to investigate the potential system architectural constructs and identify potential security threat models and associated properties that emerge in the use of composable hardware platforms. The overall objectives of the SECCOM project are to unencumbers the opportunities of composable systems, and it comprises activities and tasks through which the security and therefore resilience of a composed platform can be reasoned and verified. You will be hosted by Prof. John Goodacre within the SECCOM (Securing Composable Hardware Platforms) project, a UKRI/EPSRC managed project funded by the MoD/Dstl. Offers for the position will therefore be conditional on passing an identity check with Dstl.

Applications are invited for a Research Associate to work as part of a EPSRC-funded team in the “SPINS: Synthetic biology Pipeline for the Investigation of Novel Spidroins” project based within the Manchester Institute of Biotechnology. This project involves the University of Manchester and the University of Sheffield. The aim of the project is to enable rapid microbial production of novel, bespoke spider silks with predictable spinning properties, expanding the scope of viable applications of these versatile materials. You will have skills in computational biology, aligned with the requirements of synthetic biology and genome engineering. The appointee will join a team of researchers in the SPINS consortium, in particular working with 2 PDRAs and a technician based in the Manchester Institute of Biotechnology and in the Department of Materials and a PDRA in University of Sheffield. A strong commitment to team-based work is required with strong background in bioinformatics, and genomics and transcriptomics data analysis, and a solid understanding of the concepts of modern molecular and synthetic biology. This 3-year project will be supervised by Professor Rainer Breitling.

Applications are invited for a 2-year post-doctoral position focused on the development and application of a chemical reactor for the analysis of heterogeneous reactive mixtures by novel high-resolution NMR techniques. Funded by The Leverhulme Trust, through a grant on “NMR Method for in Situ Monitoring of Heterogeneous Reactions”, the appointment will be made as part of a broad project including 2 other researchers in NMR Spectroscopy and Organic Chemistry (Department of Chemistry). You will work closely with Dr Julien R. Landel at the Department of Mathematics, who has strong expertise in experimental fluid mechanics and multiphase flows. You will also work in collaboration with Prof. Jordi Bures and Dr Ralph Adams at the Department of Chemistry, who have been awarded co-funding for this project. The research will be carried out in the fluid mechanics laboratory facilities of the Manchester Centre for Nonlinear Dynamics (MCND) headed by Prof. Anne Juel. This project offers an excellent opportunity for a suitable candidate to build a broad skill set in fluid mechanics and chemical engineering, with applications in chemistry and NMR spectroscopy, and to contribute intellectually to other projects within the research group. The aim of the project is to design, test and develop a stirring fluid mechanics device for the mixing of heterogeneous mixtures for chemical analysis by NMR spectroscopy. NMR spectroscopy is the most advanced techniques to analyse chemical reactions. However, it is currently limited to homogeneous (single phase) liquid mixtures. In this research project, we will explore novel chemical reactor designs, based on existing prototypes tested in the research groups of Landel, Bures and Adams, in order to overcome the limitations of NMR spectroscopy for heterogeneous reactive mixtures. In collaboration with two other researchers based in chemistry and NMR spectroscopy, this project has the potential to unlock the use of NMR spectroscopy for a broad range of applications, in order to allow the identification, quantification and structure determination of all chemical components in heterogenous mixtures. Indeed, in many areas (e.g. chemical process development, quality control, food science, metabolomics, polymer science) the majority of the samples of interest are heterogeneous mixtures, and here NMR could play a pivotal role due to its non-destructive and quantitative nature.

You will have a Ph.D. degree or equivalent in developmental biology, molecular biology or a related area of research, and a BSc (hons) in a relevant biological sciences discipline. You will have extensive and up-to-date theoretical and practical knowledge in at least one of the following: developmental biology; molecular biology; regeneration. You will have excellent technical skills and extensive experience in several of the following techniques: zebrafish transgenesis, CRISPR/Cas9 mutagenesis in zebrafish, zebrafish larvae live imaging, fluorescent in situ hybridisation techniques, use of image analysis software, fluorescence microscopy. This is a full-time fixed term appointment starting 01 September 2023, or as soon as possible thereafter, and is funded for 36 months (extendable for 24 more months). The School is committed to promoting equality and diversity, including the Athena SWAN charter for promoting women’s careers in STEMM subjects (science, technology, engineering, mathematics and medicine) in higher education. The School holds a Bronze Award for their commitment to the representation of women in the workplace and we particularly welcome applications from women for this post. All appointments will be made on merit. For further information, please visit: https://www.bmh.manchester.ac.uk/about/equality/ ​​​​​​​

Applications are invited for a Postdoctoral Research Assistant with expertise in adult stem cells and biomaterials. The position is available for a fixed term of 18 months from time of appointment. This project is associated with an exciting new EPSRC Healthcare Technologies Grant and applicants will have the opportunity to work in an interdisciplinary group to assess the potential of novel 3D printed biodegradable polymers and hybrid scaffolds for osteochondral regeneration on using adult stem cells and in vitro bone/osteochondral models. Successful candidate will have the opportunity to work in a multidisciplinary setting at the Henry Royce Institute at the University of Manchester. Applicants should possess or be close to obtaining a PhD in cell biology or biomaterial science. They should be highly experienced in stem cell culture, molecular biology techniques and 3D cell culture with expertise in using a range of cell culture, molecular biology and immunohistochemical techniques, including RNA extraction, rt-PCR, immunohistochemical and immunofluorescence staining. Experience with biomaterial, bioreactors and various imaging techniques will be considered an advantage. Post will be based at the University of Manchester and The Henry Royce Institute, with the opportunity to work with collaborators with expertise on polymer synthesis (Dr Georgiou, Imperial), hybrid synthesis and additive manufacturing (Prof J Jones, Imperial ) and animal models (Prof G Blunn, Portsmouth/RVC)

Applications are invited for the role of Post-Doctoral Research Associate in Bioinformatics to work in translational neuro-oncology in the Hamerlik lab in Manchester. The post involves dealing with multi-omic data analysis and storage, focusing particularly on data from spatial multi-omic profiling of brain metastases (incl. GeoMx platform, Mass Spectrometry Imaging). Tasks range from low-level QC and mapping through to statistical analysis, data visualization, machine learning and biological interpretation. The post-holder will also help develop tools and workflows, contribute to experimental design prior to data collection and will contribute to writing up work for journal papers and presentations. There will also be opportunities to contribute to training and education activities e.g. through attendance at courses, workshops and conferences. The successful applicant will have, or be about to obtain, a PhD or equivalent in a relevant discipline and must be familiar with high-throughput sequencing data analysis methods. Experience of programming in a language relevant for Bioinformatics is essential (e.g. R, Python, C/C++ or Java) as are good communication skills. You should also have good recording and curation skills to enable high project throughput. Candidates with strong statistical data analysis skills are particularly encouraged to apply.

The Sustainable Materials Innovation Hub works at the interface between the Sustainable Futures research platform at the University of Manchester and the Henry Royce Institute, the UK’s national lab for advanced materials. The Hub supports innovation in sustainable plastics and multi-materials, with a particular emphasis on the translation of best practice into industry and policy. The team is necessarily interdisciplinary, with polymer scientists working with economists, social scientists and life-cycle experts to co-create robust solutions to managing plastic from creation to end-of-life. We are recruiting an enthusiastic and collaborative post-doctoral research associate to join our team to work on an ambitious new project with electric vehicle manufacturer Polestar. The role will involve improving the sustainability of the diverse array of automotive plastics through increasing recycled content, developing new carbon-negative polymers and improving recyclability. The project will critically evaluate sustainability, safety and scalability throughout the project to enable translation into Polestar pilots and prototypes. The inclusion of recycled content and the development of bio-based polymers will lower the carbon footprint of automotive parts towards a greenhouse gas free future for automotive plastics. You should have, or be working towards, a PhD or equivalent in either polymer chemistry, engineering, circular economy, life cycle assessment or a closely related field. Expertise in sustainability is essential, ideally with experience in polymers, circular economy, recycling or carbon negative materials. You should be capable of working under your own initiative, collaborating with others, and should evidence excellent communication and organisational skills. Our School and our Hub are committed to Athena SWAN principles to promote women in science and to broader equality, diversity and inclusion efforts. The University of Manchester values a diverse workforce and welcomes applications from all sections of the community.

The Department of Engineering for Sustainability resides in The School of Engineering at The University of Manchester. Our department has a rich heritage and a tradition of excellence in research and teaching.  We have over 40 members of academic staff in the department supported by dedicated administration and technical support groups. Research projects in the department are wide-ranging, and include theoretical and computational research, experimental studies, resilient systems, design and management, structural dynamics, and climate change studies. Academic staff members within the department deliver world-class teaching and supervision to over 1000 undergraduates, over 600 taught postgraduate students and over 250 postgraduate research students. Our work is applicable to diverse industry sectors and interests, for example: aerospace, manufacturing, civil, process industries, medical, nano-engineering, energy, environment, transport and nuclear.  The 2014 Research Assessment Exercise reflects our research strength, where 100% of our impact on industry and policy was ranked as world leading or internationally excellent. The Department has a strong links with industry and international collaborations with European, Asian, North, and South American research groups.

We are looking for a holder of University degree in computational biology, bioinformatics, statistical genetics or applied mathematics and an experience in analysis of big data, genetics, transcriptomics and other “omics”. The post holder with contribute to investigations of human transcriptome and epigenome to dissect the molecular underpinnings of hypertension and identify its new diagnostic and therapeutic targets. Excellent programming skills and knowledge of recent developments in omics-based research are essential.

This is an exciting opportunity for a highly motivated and ambitious research associate to join the Leukaemic Stem Cell Niche (LSCN) group at the University of Manchester, funded by a Leukaemia UK John Goldman Fellowship awarded to Dr Simona Valletta. You will hold a PhD in a relevant area, and you will be an expert in normal and malignant haematopoiesis, leukaemia and ageing biology. A strong publication record in high-impact peer-reviewed journals is a prerequisite, as is the ability to work independently and as part of a team. You will have strong communication and organisational skills, with the ability to manage and independently lead, innovate, and complete your own research project. Bioinformatics expertise (RNAseq, ATACseq, single cell analysis) including coding in “R”, is desirable.

 

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Research Associate (Manchester Institute of Education)

Deadline : 21/09/2023

View details & Apply

 

This is an exciting opportunity to be the Manchester site Research Associate / Research Co-ordinator in the CONNECT study.  This post will be an 8 month post to cover maternity leave. This is a multi-site Wellcome Trust funded project which aims to identify relapse signatures in people with psychosis using active and passive digital monitoring and data collection methods. The post holder will manage all aspects of the project for the study site; liaise with the local and national project leads, researchers, patient and public contributors; as well as managing two research assistants. Candidates with an interest in digital mental health and serious mental health problems would be particularly encouraged. Candidates should have research management experience, understand mixed-methods studies, skills in psychological assessment, demonstrable project management skills, and excellent interpersonal and communication skills.

We are seeking an individual with a passion for open, transparent, and reproducible research, who has a range of experience across academic disciplines, to act as Research Associate at the University of Manchester working on the IOSSC project. Open-source software and code are gaining evermore importance under the emerging open research paradigm. On one hand, there is the theory and optimal processes according to frameworks, but on the other hand there are the real-world practices of researchers and engineers at the university. The proposed project will therefore investigate the “lived software culture” at the university through establishing a snapshot of current practices and gaps in provisions to be then able to inform the future Research Software Policy and other frameworks and technical applications the university strives to implement in the future. The project will help to create a sustainable open software environment at the university and will be closely aligned with the Research Lifecycle Programme II (RLPII).

Applications are invited for a Research Associate in Pharmacokinetic Translation PBPK modelling, in the Division of Pharmacy and Optometry. The post will be tenable on a fixed term basis of 24 months in the first instance. Working under the umbrella of the Centre of Applied Pharmacokinetic Research (CAPKR) group, you will be fully involved in a CAPKR-funded project entitled ‘Liquid Biopsy and Endogenous Biomarkers to enhance or replace specific DDI studies in Patient Populations’. You will hold a PhD in a biomedical, pharmaceutical or systems modelling research area, and have a background in determining activities of drug metabolizing enzymes and/or transporters using different in vitro systems and experience in physiologically-based pharmacokinetic (PBPK) modelling incorporating in vitro-in vivo extrapolation. Emphasis will be placed on a developing publication record.

Two Postdoctoral Research Associates in Neurorobotics are required for a period of 48 months to work on the Horizon/InnovateUK project “PRIMI: Performance in Robots Interaction via Mental Imagery. This is a collaborative project of the University of Manchester’s Cognitive Robotics Lab with various academic and industry partners in the UK and Europe. PRIMI will synergistically combine research and development in neurophysiology, psychology, machine intelligence, cognitive mechatronics, neuromorphic engineering, and humanoid robotics to build developmental models of higher-cognition abilities – mental imagery, abstract reasoning, and theory of mind – boosted by energy- efficient event-driven computing and sensing. You will carry out research on robot neuro/cognitive architectures, using a combination of machine learning and robotics methodologies. A PhD in Computer Science, Robotics, Artificial Intelligence or allied disciplines is required. Excellent programming skills are essential, as well as robotics and/or machine learning skills. Previous experience and publication track record in robot cognitive modelling is an essential requirement. One post requires expertise in computational neuroscience (e.g. spiking neural networks) for robotics, and one in neuro-cognitive architectures. You will be working collaboratively as part of the Cognitive Robotics Lab at the Department of Computer Science at the University of Manchester under the supervision of Professor Angelo Cangelosi, (close collaboration with the other project partners will also be required).

This project will study how transcription factors select and activate their target enhancers. It combines high-throughput and single locus-based approaches in tractable in vitro systems (human embryonic stem cells) with state-of-the-art computational approaches to study the dynamic recruitment of multiple transcription factors at cell type-specific enhancers and define their individual contributions to gene expression. Results are expected to clarify how specific cell fates are established, addressing a fundamental question in biology and paving the way for efficient cell reprogramming and the generation of specific cell types. The laboratory is part of a larger research group using genomic approaches and is located in a cutting-edge multidisciplinary centre for biomedical research. 

We are seeking a proactive and experienced post-doctoral research associate with expertise in qualitative research methods to join the eVOLVE programme (Evaluating the effectiveness of the Saving Babies’ Lives Care Bundle Version 2 on reducing perinatal mortality). eVOLVE is a NHS England-funded programme to evaluate the impact of implementation of NHS England’s Saving Babies’ Lives Care Bundle Version 2 (SBLCBv2) on perinatal outcomes and maternity services. eVOLVE is hosted by the Maternal and Fetal Heatlh Research Centre at the University of Manchester, which delivers a world-leading portfolio of translational research to prevent complications of pregnancy and perinatal mortality. The post holder will lead on delivering workstream 3 of the programme to evaluate the views and experiences of service users and providers about maternity care in relation to implementation of the SBLCBv2. The successful candidate will have a track record in leading qualitative research in a healthcare/social science related discipline. They will have a proven track record in designing, conducting, analysing and writing-up qualitative research. There is opportunity for a hybrid model of office and home-based working.

We are looking for an individual who has interest in and knowledge about issues involved in providing paediatric hearing health care, and has an awareness of research in this area.  The candidate should have experience of conducting qualitative research. The candidate should be organised, self-motivated, and passionate about working with diverse communities to ensure all have equal and fair participation in the JLA process. This is an ideal opportunity for an individual seeking post-doc experience or for someone with specialist skills in providing hearing health care and/or working with diverse communities including children and young people, collecting and analysing qualitative datasets, and using systematic techniques to review existing scientific literature.

We have an exciting opportunity to appoint a research assistant or associate to conduct important research about enabling people with learning disabilities and/or autism to attend cervical screening. The person appointed will join the Mental Health Research Group within the Division of Nursing, Midwifery and Social Work, based at the University of Manchester. This researcher will work on a new project, ‘Reducing inequity in cervical screening for people with learning disabilities and/or autism in Greater Manchester’. The successful applicant will be involved in this work, to facilitate people with learning disabilities to design a series of educational videos to enable people with learning disabilities and/or autism and their supporters to make choices and decisions about the human papilloma virus (HPV) vaccination and cervical screening. The successful candidate will conduct co-production activities, supporting an advisory group of people with learning disabilities and/or autism and various discussion groups to develop ideas for the video content and the associated educational materials.  There will also be a video for healthcare professionals involved in cervical screening. The researcher will be involved in an evaluation piloting the implementation of the videos in healthcare settings.  This will involve applications for ethical approval. The researcher will assist with liaising with the filmmaker for the project. The post will involve some travel around Greater Manchester.