Karolinska Institute, Sweden invites online Application for number of Fully Funded PhD Degree at various Departments. We are providing a list of Fully Funded PhD Programs available at Karolinska Institute, Sweden.
Eligible candidate may Apply as soon as possible.
(01) PhD Degree – Fully Funded
PhD position summary/title: Doctoral student in image acquisition and reconstruction for cardiovascular magnetic resonance imaging
Magnetic resonance imaging (MRI) provides uniquely comprehensive cardiac evaluations, serving as the reference standard for assessing the cause of heart failure by quantifying chamber volumes, ventricular function, and myocardial tissue characterization related to infarction and scarring. The biggest challenge for cardiovascular MRI (CMR) lies in the need for imaging during suspended respiration, limiting acquisition time, spatial resolution, and temporal resolution. Importantly, many cardiac patients suffer from shortness of breath and an inability to hold their breath, which makes them difficult or impossible to image using current CMR techniques. Nevertheless, the incorporation of advanced image acquisition techniques and machine learning is starting to fundamentally change what we can analyze and resolve. Specifically, our group recently introduced the sector-wise golden angle radial (SWIG) method, enabling high-quality images at high acceleration factors and unprecedented temporal resolutions in cardiac MRI, opening for novel diagnostic paradigms. As a Ph.D. student, you will continue these advancements by exploring and implementing novel image acquisition and reconstruction methods that expand the capabilities of the sector-wise acquisition paradigm. Based in a highly translational research environment, the Ph.D. project specifically seeks to (1) enable motion-adaptive image acquisitions using multi-modal sensor input; (2) couple this to developments in image reconstruction and image analysis to form a framework for motion-adaptive imaging; and (3) investigate how motion-adaptive cardiac imaging expands our understanding of complex cardiac disease. You will have access to state-of-the-art MRI systems and will directly deploy and evaluate novel research developments in a clinical environment.
Deadline : 01.Dec.2023
(02) PhD Degree – Fully Funded
PhD position summary/title: Doctoral candidate (PhD) position: Oesophago-gastric cancer
This KI centrally funded PhD project (KID-funding) is oriented towards clinical research. The PhD candidate will learn the corresponding methodology, i.e. clinical epidemiology. The project will examine factors that may improve the survival in patients who undergo surgery for oesophago-gastric cancer, including prediction of short survival, surgical approach for tumours in the oesophago-gastric junction, which postoperative complications influence the long-term survival, and postoperative follow-up strategies. Most studies will be cohort studies using data from national cohorts in Sweden and Finland, but will also include some work within a multinational randomised controlled trial. The PhD candidate will mainly conduct research of high quality. This will include drafting detailed study protocols, reading and reviewing relevant literature, collecting and reviewing research data, performing data management and statistical analysis, and writing scientific articles and a PhD thesis. Except for research, other mandatory parts of the PhD education are participation in PhD courses, research seminars and international scientific conferences. The PhD candidate is also supposed to attend the regular supervisor meetings, write monthly reports to the supervisors, and take part in our shared activities, i.e., research group meetings, work place meetings, end-of-term activities, and planning days. Information regarding PhD studies at KI is available on the homepage: www.ki.se/doctoral.
Deadline : 30.Nov.2023
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(03) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Neural Circuits
The Meletis Laboratory at Karolinska Institutet in Stockholm has an open position for a doctoral student to investigate the circuit mechanisms that control motivated behaviors. The doctoral student will investigate the in vivo role of circuits and genetically-defined neurons types in motivated behaviors (e.g. appetitive, aversive) and define circuit dysfunction in disease-relevant mouse models. The project will take advantage of advanced methods in systems neuroscience including cell-type specific in vivo imaging (e.g. photometry, miniscopes), cell-type specific manipulation during behavior (e.g. optogenetics), wholebrain circuit tracing, Patch-seq, and mapping of neuron identity using molecular methods (e.g. snRNA-seq and genetic labeling). The candidate must have excellent training in circuit or systems neuroscience, with the ambition to make significant contributions to our understanding of the organization and function of circuits that control different dimensions of motivated behaviors. The candidate must have excellent communications skills and the ability to work productively in an interdiciplinary team. Fluency in English is a requirement.
Deadline : 30.Nov.2023
(04) PhD Degree – Fully Funded
PhD position summary/title: Doctoral candidate (PhD) position: Oesophago-gastric cancer
The PhD candidate will mainly conduct research of high quality. This will include drafting detailed study protocols, reading and reviewing relevant literature, collecting and reviewing research data, performing data management and statistical analysis, and writing scientific articles and a PhD thesis. Except for research, other mandatory parts of the PhD education are participation in PhD courses, research seminars and international scientific conferences. The PhD candidate is also supposed to attend the regular supervisor meetings, write monthly reports to the supervisors, and take part in our shared activities, i.e., research group meetings, work place meetings, end-of-term activities, and planning days. Information regarding PhD studies at KI is available on the homepage: www.ki.se/doctoral. The main supervisor is Jesper Lagergren, professor of surgery, research group leader, and member of the Nobel Assembly at KI. Co-supervisors are Joonas Kauppila, professor and surgeon at the University of Oulu in Finland (and affiliated to our research group at KI), Sheraz Markar, associate professor and surgeon at the University of Oxford in the United Kingdom (and affiliated to our research group at KI), and Fredrik Mattsson, biostatistician in our group at KI. The supervisors are experts in the research field and the methodology of this PhD project.
Deadline : 30.Nov.2023
(05) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Molecular Neuroscience
The project will combine single-cell RNA-seq, spatial transcriptomics, optogenetics, genetically modified viruses, and other platforms to define the molecular organization of brain circuits, the identity of neuron subtypes, and how neuronal diversity helps explain connectivity and functional complexity. The aim is to define cell-type specific connectivity with state-of-the-art approaches that include molecular profiling of neuron subtypes and connectivity at large scale using barcoded viruses. The candidate must have experience using molecular methods to define cell types, for example single- cell RNA sequencing or spatial transcriptomics, and a strong analytical and statistical background. Strong background in neuroscience is an advantage. The candidate must have excellent communications skills and the ability to work productively in an interdiciplinary team. Fluency in English is a requirement.
Deadline : 30.Nov.2023
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(06) PhD Degree – Fully Funded
PhD position summary/title: 1-2 PHD-POSITIONS IN PEDIATRIC RESPIRATORY INFECTIONS
The research project focuses on the prevention, complications and diagnostics of severe lower respiratory tract infections in children, with a special focus on respiratory syncytial virus infections. The doctoral student will work with large datasets from the Appeasing the Wheezing database, which includes various national health registries, as well as clinical data from two prospectively collected cohorts of children with pneumonia from Sachs’ Children and Youth Hospital. The tasks of the doctoral student will involve participating in discussions regarding the final study design, driving the projects forward, data processing, statistical analysis (using STATA and SAS), and scientific writing under supervision. The doctoral student is also encouraged to attend relevant seminars at the department and present the study results at national and international conferences.
Deadline : 27.Nov.2023
(07) PhD Degree – Fully Funded
PhD position summary/title: Doctoral position in ”Gene editing using biological nanoparticles”
We are seeking a highly motivated person to join the group of Professor Samir EL Andaloussi as a Ph.D. student to work on the development of the loading of Cas9-RNPs into natural nanoparticles. The work will involve the engineering of nanoparticles for targeted delivery to the CNS, mainly by injection directly into the CNS. This would involve the development of novel loading systems and optimization of the editing in vitro before in vivo applications in relevant disease models. The successful candidate will be responsible for all aspects of laboratory work in the project and drive the project forward. He/She will furthermore have many opportunities to develop their own projects within the framework of the larger project goals. In addition to the main supervisor Samir EL Andaloussi, the student will have two co-supervisors: Ass. Prof. Joel Nordin and Senior researcher Xiuming Liang. The successful candidate will take part in all research-related activities such as group meetings, departmental seminars, relevant international meetings, supervision of other students and researchers, if necessary, as well as contribute to common lab routines. Finally, the PhD student will work to fulfill the course requirements of the PhD program as outlined in the relevant rules and documentation available at the ki.se website
Deadline : 23.Nov.2023
(08) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in Bioinformatics study of human skin wound healing
The chronic non-healing wound is a common and severe medical problem with unclear pathogenesis. The discovery of non-coding RNAs (ncRNAs) as powerful gene regulators provides hope in the quest to develop novel RNA-based treatments for a wide variety of diseases; however, the role of ncRNAs in human skin wound healing remains largely unexplored. We aim to reveal the expression and functional signatures of ncRNAs (primarily focusing on microRNAs, circular RNAs, and long ncRNAs) in human skin wound healing, and to identify ncRNAs that may be targeted in wound therapy. The current method spectrum of the group is centered around molecular biology, cell biology and biochemistry with human cells and tissues as well as mouse models but will be expanded. We are looking for a doctoral student who will implement bioinformatic approaches to analyze data generated with various high-throughput technologies to profile expression and modification of RNAs, RNA-protein-DNA interactome, chromatin accessibility and DNA methylation in human skin/wound tissues and cells. The work will include design of study, data processing, quality control, statistical analyses, data interpretation and presentation of findings in the form of scientific publications. We offer a very stimulating and welcoming working environment in a group of motivated co-workers with diverse competencies.
Deadline : 27.Nov.2023
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(09) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in pharmacoepidemiology
The aim with any IBD medication is inflammation free remission for the patient. To what extent this is achieved in routine clinical practice, outside the pivotal trials (almost always restricted to adults fulfilling strict inclusion criteria, far from routine clinical practice in pediatrics) is currently unknown. It is currently even unknown how well longitudinal data on inflammatory status can be captured using routinely collected data in Swedish IBD patients today. Real-world comparisons of the safety of different new targeted immunomodulatory treatments in childhood-onset IBD patients is currently scant at best. Until now, almost all patients have been treated according to a more or less strict “treatment ladder”, making fair comparisons between drugs at different steps in the ladder all but impossible. With a rapidly increasing choice of drugs, more and more alternatives at a given “step” in the ladder it will be possible to better than ever before describe the true comparative risk of infections in childhood-onset IBD patients exposed to different immunomodulatory drugs.
Deadline : 23.Nov.2023
(10) PhD Degree – Fully Funded
PhD position summary/title: PhD position in immunology/immunotherapy
We are looking for a highly motivated individual who has a strong documented interest in immunology, tumor biology and cellular immunotherapy, and ideally with proven skills in molecular biology and genetic engineering. The doctoral candidate will work in the team of Arnika Wagner on developing new engineered surface receptors for NK cells and investigating the anti-tumor capacity, the potential for combination therapies as well as potential off-target and side effects of these genetically modified NK cells. The project entails working with expansions and genetic modification of NK cells from healthy donors and patients with Multiple Myeloma. The methods involve immunological, molecular and cell biology methods, such as genome editing and genetic modification techniques, antibiotic-free cell culture under GMP-like conditions, multiparametric flow cytometry, molecular cloning and virus production. In addition, assays to assess transcriptional activity, metabolism and secretome will be performed. We expect that the successful candidate will lead the project under supervision and will gradually acquire independence in planning, executing, analyzing and presenting data. We collaborate with several research groups both nationally and internationally, and the candidate will play an active role in driving the part of collaboration related to their project. Excellent communication skills with the ability to present results clearly, work co-operatively as part of a team as well as independently, with strong attention to details are essential. Personal suitability is of great importance when evaluating the applicants.
Deadline : 22.Nov.2023
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(11) PhD Degree – Fully Funded
PhD position summary/title: Doctoral (PhD) student position in epidemiology
According to the latest report by the Intergovernmental Panel on Climate Change (IPCC), it is “virtually certain” that anthropogenically-driven global warming has led to an increased frequency, duration and intensity of heatwaves since 1950, a trend that is foreseen to continue in the coming decades. Concurrently, cold spells in several mid-latitude regions continue to be the norm, in part due to enhanced temperature variability. This points to the urgency of reducing the impacts on the most vulnerable by developing new recommendations and long-term mitigation strategies.
Deadline : 21.Nov.2023
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(12) PhD Degree – Fully Funded
PhD position summary/title: PhD position in forensic psychiatry
The successful applicant will work on projects related to pharmacological treatment in forensic psychiatry. The project will leverage advanced epidemiologic designs and high-quality Swedish registry data. The results are expected to provide critical information for health care providers about the risks and benefits associated with different pharmacological treatment, in order to improve treatment outcomes of patients in forensic psychiatric care.
Deadline :16.Nov.2023
About The Karolinska Institute, Sweden – Official Website
The Karolinska Institute sometimes known as the (Royal) Caroline Institute in English is a research-led medical university in Solna within the Stockholm urban area of Sweden. The Nobel Assembly at the Karolinska Institute awards the Nobel Prize in Physiology or Medicine. The assembly consists of fifty professors from various medical disciplines at the university. The current rector of Karolinska Institute is Ole Petter Ottersen, who took office in August 2017.
The Karolinska Institute was founded in 1810 on the island of Kungsholmen on the west side of Stockholm; the main campus was relocated decades later to Solna, just outside Stockholm. A second campus was established more recently in Flemingsberg, Huddinge, south of Stockholm.
The Karolinska Institute is Sweden’s third oldest medical school, after Uppsala University (founded in 1477) and Lund University (founded in 1666). It is one of Sweden’s largest centres for training and research, accounting for 30% of the medical training and more than 40% of all academic medical and life science research conducted in Sweden.
The Karolinska University Hospital, located in Solna and Huddinge, is associated with the university as a research and teaching hospital. Together they form an academic health science centre. While most of the medical programs are taught in Swedish, the bulk of the PhD projects are conducted in English. The institute’s name is a reference to the Caroleans.
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