Postdoctoral Fellowship (08) at Saint Louis University, Missouri, USA

This is a full-time Postdoctoral Researcher role at Saint Louis University.

What can the Tse lab provide for Postdocs?

Scientific freedom within the scope of the lab. The goal of a postdoc is to conduct compelling and applicable research while providing trainees with other non-science related skills for future career advancements. If agreed upon, PI will also involve his postdoctoral trainees in various tasks that cultivate skills necessary for independent investigation, including grant writing, peer-reviewing, laboratory management, and administration.

The Ferris lab at Saint Louis University in St. Louis, MO, is seeking a full-time postdoctoral research associate in the fields of tumor immunology and autoimmunity. We study the dendritic cells required to mount adaptive T cell responses in the context of tumors and autoimmunity to better understand tumor evolution and identify novel therapeutic strategies that can improve patient outcomes. The successful candidate will be highly motivated and intellectually invested. They will have the opportunity pursue their own ideas that are relevant to the overall goals of the lab and drive their own research projects.

Dr. Ferris is an Assistant Professor in the Department of Molecular Microbiology and Immunology. MMI houses a diverse variety of research groups studying virology and innate and adaptive immune responses in the context of viral infection, cancer, and autoimmunity. MMI is a highly collaborative community, meaning the successful candidate will have the opportunity to form relationships with many different laboratory groups and faculty members.

The postdoctoral fellow at the Department of Psychiatry and Behavioral Neuroscience at Saint Louis University School of Medicine will collaborate closely with a multidisciplinary research team focused on investigating the epidemiology of suicide/self-harm, suicide prevention, intervention, and other pertinent mental health issues. The successful candidate will contribute to ongoing research projects while also pursuing their own research agenda in line with the department’s objectives.

The Warren Lab (in the Department of Biology at Saint Louis University is seeking a postdoctoral research associate to join our team seeking to reveal the physiological mechanisms that enable animals to survive severe hypoxia and anoxia. This position is funded by a recent grant from the National Science Foundation (award #2421029) to carry-out studies of neurophysiological function and gene expression in the brain of anoxic turtles. Our lab has recently succeeded in culturing primary neurons from the cerebrocortex of turtles and demonstrated they possess a functional neuronal phenotype. The person hired to fill this position will lead studies of the membrane properties of these isolated neurons in response to anoxia using whole-cell patch-clamp recording techniques.

The Warren Lab is one of many that form part of a vibrant community of neuroscience researchers within Saint Louis University’s Institute for Translational Neuroscience. The St. Louis region is also home to many academic and industrial leaders in the fields of neuroscience and physiology. The position will include travel to conferences and the formation of collaborations with researchers at the University of Toronto and Aarhus University.

As a Postdoctoral Fellow, your work will directly contribute to our understanding of complex biological processes, with a focus on:

• Molecular, Cell Biology, and Biochemical Techniques: Including mammalian cell culture, transfections, recombinant protein characterization, and enzyme kinetics.
• Cellular Studies: Isolation and culture of various blood cells, endothelial cells, and other cell types.
• Assay Expertise: Performing and analyzing data from Western Blots, qPCR, ELISA, flow cytometry, Immunohistochemistry, and coagulation assays.
• Animal Models: Conducting in vivo experiments with small laboratory animals (tail-vein injections, blood collection, surgical procedures in mice).

We are seeking a highly motivated Postdoctoral Fellow or Research Assistant to join our research team. Under the general direction of the Principal Investigator, you will contribute to innovative research projects by performing complex experiments, analyzing data, and supporting the development of new methodologies. This role involves hands-on laboratory work, independent research, and collaboration with multidisciplinary teams to advance scientific knowledge in [molecular biology, mitochondrial biology/ cardiology, and or heart failure].

The Antony Laboratory is seeking multiple highly motivated Postdoctoral Research Associates to join a dynamic, interdisciplinary team investigating the molecular and structural mechanisms of enzymes involved in DNA repair, recombination, mRNA processing, and long‑range electron transfer. Our lab applies advanced structural and biophysical methodologies including cryo‑electron microscopy (cryo‑EM), X‑ray crystallography, single‑molecule fluorescence, and enzyme kinetics to elucidate how large macromolecular assemblies carry out essential biological processes. These positions are supported by NIH (NIGMS/NCI) and DOE funding and offer the opportunity to work on high‑impact structural biology problems with broad relevance to genome maintenance and energy transduction.

A postdoctoral research position is available in the laboratory of Dr. Gucan Dai in the Edward A. Doisy Department of Biochemistry and Molecular Biology at Saint Louis University School of Medicine. We are seeking a highly motivated and skilled scientist with a strong background in biophysics, with a focus on ion channel research. Prior experience with patch-clamp electrophysiology and advanced microscopy techniques is highly desirable.

The Dai lab investigates the fundamental mechanisms of ion channels in excitable membranes using a multidisciplinary approach. Our NIH-funded research integrates structural biology, chemical biology, genetics, fluorescence microscopy, and electrophysiology. The lab is equipped with two cutting-edge patch-clamp electrophysiology/fluorescence imaging systems, including a frequency-domain fluorescence lifetime imaging microscopy system.

Research Focus Areas:

Voltage-sensing mechanisms of voltage-gated ion channels – These channels are key players in conditions such as chronic pain, cardiac arrhythmias, and epileptic seizures. Trainees will gain hands-on experience with advanced techniques like patch-clamp fluorometry (PCF), Förster resonance energy transfer (FRET), and the use of fluorescent noncanonical amino acids (ncAAs).

Lipid-mediated regulation of ion channels and membrane dynamics – This research explores the role of lipids in the regulation of ion channels, with implications for inflammatory and neuropathic pain, Alzheimer’s disease, epilepsy, and viral infections. Relevant techniques include whole-cell fluorometry, calcium imaging, TIRF microscopy, and fluorescence lifetime imaging.