Postdoctoral Fellowship (22) at Karolinska Institute, Sweden

The Stagkourakis Lab is recruiting for a highly independent postdoctoral researcher that can integrate within our existing team pursuing systems neuroscience projects. The lab is based at SciLifeLab (Sweden’s national center for advanced life science infrastructure) and the Department of Neuroscience, Karolinska Institute. Our research focuses on the neural control of survival and homeostatic behaviors (including aggression, fear, and feeding), using large-scale neural recordings, advanced imaging, causal perturbations, and quantitative analysis in freely moving mice. For an overview of the lab’s research program and publications see here: https://www.scilifelab.se/researchers/stefanos-stagkourakis/

The Stagkourakis labs is embedded in the Dept. of Neuroscience at Karolinska Institutet and is part of SciLifeLab, a Swedish national center for large‑scale molecular biosciences and cutting‑edge infrastructure. Our research focuses on the neural basis of prototypical behaviors, including aggression, defensive states, and parental care, using a combination of advanced behavioral paradigms, in vivo recordings, and circuit manipulations.

The Nyberg Lab, based at the Department of Medicine, Huddinge and SciLifeLab, develops evolved AAV capsids and state-controlled gene-expression technologies for in vivo viral engineering. This project brings the two laboratories together to build a shared experimental platform that neither lab could develop alone.

The postdoc will be primarily based in the Stagkourakis Lab for day-to-day experimental work, but will be fully embedded in both laboratories, with structured co-mentorship from Nyberg and regular integration into both research environments. For more information on the Stagkourakis Lab see here, and for the Nyberg Lab see here.

As a post-doctoral researcher, you will join our team, a leading group in DNA nanotechnology specialized in creating molecular tools for life-science research (http://www.hogberglab.net/). You will contribute to the Dura-store project that is a part of the European Innovation Council’s Pathfinder Challenge for DNA-based digital data storage, aiming to use bio-inspired solutions to address fundamental limitations of the current manifestations of the technology in terms of data stability and dynamic data operability in vitro and in vivo. You will be joining our efforts to move the technology’s capabilities towards that of conventional digital data storage by developing and adopting existing bioinformatics tools for data encoding, decoding and error correction in our system as well as for probe design to allow different data operations such as random access and deletion in the system.

If you are interested in helping us to create the new generation of molecular data storage solutions, please apply.

Also note: While the role focuses on nucleic acids, our interdisciplinary approach often benefits from a broad computational toolkit; candidates who are interested in bridging these projects with insights from related fields—such as de novo protein design—to enhance our molecular systems are highly encouraged

You will join our team, a leading group in the field of DNA nanotechnology specialized in creating molecular tools for life-science research (http://www.hogberglab.net/). You will contribute to the ERC Advanced Grant project qScope, where you will create and improve existing bioinformatic tools and network algorithms to help us to map RNA or protein molecules in tissue samples using a method called DNA-microscopy. This technique aims to allow the reconstruction of the relative spatial positions of biomolecules using exclusively DNA-sequencing information based on artificial molecular networks (neighbour-neighbour interaction matrices) created experimentally in the sample. This is essentially about turning the sequencer into a microscope that uses DNA sequence, not light, as a carrier of spatial information.

If you are interested in helping us to create the new generation of spatial omics, please apply.

Also note: While the role focuses on nucleic acids, our interdisciplinary approach often benefits from a broad computational toolkit; candidates who are interested in bridging these projects with insights from related fields—such as de novo protein design—to enhance our molecular systems are highly encouraged.

The postdoctoral researcher will be involved in a research program with the overall aim to study the impact of urban living on wellbeing and health. The project applies advanced quantitative epidemiological methods to study associations between exposure to various environmental factors and public health. Qualitative methods will also be included to explore experiences on how environmental factors influence health. A particular aim is to assess how overcrowding and inadequate housing, combined with socioeconomic disadvantage, affect children’s health, development, and school performance. This part of the program combines a large-scale register study with an intervention for children with asthma and allergies. Aims are to (1) analyze links between overcrowding and children’s physical and mental wellbeing and school outcomes, (2) evaluate whether home visits can mitigate negative housing effects, and (3) inform healthy housing design through dialogue with parents and stakeholders in environmental health and urban planning. The qualitative part will consist of parental focus-groups interviews and aim to explore indoors- and outdoors impact on children’s health in vulnerable areas. More information about the program can be found here. 

Du ska ha gedigen utbildning och erfarenhet inom forskning om psykologiska interventioner, kliniska prövningar och statistik. Tjänsten kräver att du är kliniskt utbildad (legitimerad inom ditt yrke), behärskar svenska flytande (i både tal och skrift) samt har god kompetens i Stata, R eller liknande statistisk programvara.

Du ska vara en mycket engagerad person som uppskattar utmaningar och som trivs med att arbeta i ett stort multidisciplinärt team bestående av både forskare och kliniker. Du ska känna dig bekväm med att kommunicera med både barn och deras vårdnadshavare.

Utöver dessa krav är det meriterande med tidigare erfarenhet av arbete inom barn- och ungdomspsykiatri. Följande erfarenheter värderas särskilt högt: arbete med studier om återfallsprevention, deltagarbaserade metoder (t.ex. samskapande och samutveckling av interventioner), ekologiska momentana mätmetoder samt digitala interventioner.

För att anställas som postdoktor krävs avlagd doktorsexamen eller en utländsk examen som bedöms motsvara en svensk doktorsexamen. Detta behörighetskrav ska vara uppfyllt senast vid tidpunkten då anställningsbeslutet fattas. Det är meriterande om du har avlagt din doktorsexamen inom de tre senaste åren, om det finns särskilda skäl kan din examen ha avlagts tidigare.

Four-dimensional flow magnetic resonance imaging (4D Flow MRI) has emerged as a powerful imaging technique, providing unique full-field mapping of blood flow across various cardiovascular compartments. However, acquisition, reconstruction and analysis still require complex analysis and clinical limitation in terms of manual data handling, spatiotemporal resolution limits, and so on still limit effective modality usage. The incorporation of machine learning and advanced MR-physics implementations is, however, starting to fundamentally change what can be analysed and resolved. Specifically, our group has shown how the use of super-resolution networks and physics-informed image processing now allow for usage of 4D Flow MRI through previously inaccessible domains, opening for novel diagnostic paradigms.

The postdoctoral researcher will continue these efforts on quantitative imaging, targeting data-driven data enhancements using dedicated neural networks and mathematical algorithms to streamline analysis and improve physiological insight. Work may include further enhancement of existing data-driven approaches into more advanced purpose-built setups (expanding into Diffusion, Transformer, or Foundation Model networks) as well as proposing novel utilities for higher-dimensional data analysis.

Making use of our translational team, work is expected to include evaluation in existing patient-specific models, benchtop validation setups, on dedicated and available MR-systems, as well as clinical patient cohorts, serving our overall goal of improving our understanding of hemodynamic risk through various cardiovascular compartments.

Phase-contrast MRI plays a crucial role in cardiovascular flow quantification, with three-dimensional measurements of time-resolved flow (4D Flow) presenting a unique opportunity to deepen our understanding of cardiovascular hemodynamics. However, challenges like long scan times, motion artifacts, and the trade-off between spatial and temporal resolution remain significant barriers for widespread adoption. The incorporation of advanced image acquisition techniques is starting to fundamentally change what can be analyzed and resolved. Specifically, our larger group has shown that innovations in sequence development to enable high-quality image recovery at higher acceleration factors and at unprecedented spatiotemporal resolutions, opening for new diagnostic paradigms.

Your focus will be on developing novel pulse sequences and accompanying image reconstructions for 4D flow imaging, seeking ways to efficiently image volumetric flow in the heart and large vessels. Making use of our translational team, the methods developed will be evaluated using dedicated on-site MRI scanners and in clinical patient cohorts, serving our overall goal of improving our understanding and use of MRI for next-generation cardiovascular care and to translate novel imaging innovations directly into clinical practice.

You will have the opportunity to work at the interface between advanced laboratory research and clinical studies. Your work will be carried out in close collaboration with colleagues at the Public Health Agency of Sweden and leading researchers in Belgium, France, and Ireland.

The study aims to evaluate differences in immune responses among individuals who have received primary vaccination either intradermally (ID) or subcutaneously (SC), and who, within the study, receive a booster dose (often a third dose).

The study is crucial for guiding future vaccination recommendations for protection against mpox in Sweden, within the EU/EEA, and globally. The project is funded by the EU (HaDEA/HERA). The results will be of great interest to both high-income countries and low- and middle-income countries. Mpox is spreading globally, and vaccine availability remains limited.

Your main responsibilities will include:

• Cultivating virus in an accredited BSL3 laboratory
• Performing analyses on samples from vaccinated individuals
• Analyzing and compiling results for reports to funding bodies and for scientific publication
• Supporting the management and storage of incoming samples from the clinical trial in collaboration with colleagues at the Public Health Agency of Sweden and international partners

The work will primarily be carried out at the premises of the Public Health Agency of Sweden, but the employment will be with Karolinska Institutet. The position requires security clearance for work in BSL-3. When recruiting for a security-classified environment, a security clearance is carried out.

The successful candidate will conduct a project focusing on the impact of one of already identified dysregulated niche factors in therapy response of acute and chronic myeloid leukemia under the supervision of the group leader (Prof. Hong Qian). In addition, the candidate is also expected to participate in collaborated projects and supervision of junior students in the group during her/his postdoc training.

To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.

We are looking for a highly self-motivated person with a strong background in cellular and molecular biology with a keen interest in leukemia microenvironment/niche and hematopoiesis in general. Experience in working with tumor microenvironment, multi-color flow cytometry, gene-editing, and mouse modeling is highly desired; and good ability to communicate in English (written and verbal) is required. The applicant must be able to work flexibly and in a high-paced research environment.

It is considered as a merit if the applicant has experience in flow cytometry, imaging, laboratory animal work (as documented by FELASA C or equivalent) with at least 1-3 years hands on experience working with mice or bioinformatics analysis tools.

As a postdoctoral researcher, you will join our ambitious team, a leading group in computational drug discovery with a strong focus on infectious diseases (https://luttenslab.netlify.app). The successful candidate will carry out experimental high-throughput screens, perform molecular docking calculations, and design antiviral candidates as part of the ongoing DDLS project.

You will collaborate closely with dedicated scientists across leading research infrastructures that support our work and play an active role in mentoring and training junior researchers in the lab. As part of the team, you will help implement and validate cutting-edge computational technologies developed in the lab. If you are motivated to apply your interdisciplinary skill set to the development of urgently needed antiviral therapies, we strongly encourage you to apply.

Professor Marie Löf, leads the research group IMPACT (Innovative use of Mobile Phones to promote physical ACTivity and nutrition across the lifespan) (https://ki.se/en/medh/research-at-the-department-of-medicine-huddinge/bionut-unit/research-at-bionut/the-impact-research-group-marie-lof at Karolinska Institutet. The group (>35 people) conduct research in digital health with development of interventions with focus on health care services with special emphasis on pregnant women and children. We are now looking to strengthen the group with a postdoctoral researcher who has a strong profile in large‑scale data management and analysis. The person will work with both data analysis and reporting of existing data, as well as participate in projects that are in the start‑up phase. The role also includes some project coordination and supervision. We are seeking a motivated postdoctoral researcher who wants to lead their own research and grow together with us. The group has extensive experience in mentoring early‑career researchers and supporting their academic development.

Your goal is to help revolutionize the early detection of ovarian cancer. By bridging the gap between bench science and clinical application, you will develop and validate liquid biopsy assays using unique patient cohorts to improve diagnostic accuracy and drive implementation of new early detection approaches in clinical routines.

Key Aims:

• Assay Development: Implement and optimize high-sensitivity (epi)genetic assays for liquid biopsy analysis.
• Comparative Analysis: Directly compare various biomarker strategies in ovarian tumor cohorts to evaluate diagnostic sensitivity and specificity.
• Data Integration: Integrate multi-modal data—including epigenetic readouts and clinical markers—to build comprehensive diagnostic models.
• AI Collaboration: Work alongside computational experts to develop and refine AI-based rapid assessment tools for ovarian cancer.

As a postdoc, you will take a leading role in experimental design, data generation, quality control and interpretation, and the presentation/publication of results to drive the project forward. The ability to work independently and as part of a team is essential for this position.

The Systems Virology group comprises interdisciplinary research teams working at the interface of systems virology, immunometabolism, and host-pathogen interactions, with a particular focus on human-specific immune regulation. Our research team combines advanced wet-lab virology with multi-omics approaches to understand how viruses reprogram cellular homeostasis during infection and immune stress.

As a postdoctoral fellow, you will join an ongoing, data-rich research program and gain hands-on experience in mechanistic experimentation, integrative data analysis, and collaborative projects with strong translational relevance.

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral position(s) in adaptive immunity in cancer (up to 2)

Deadline :  02.Mar.2026

View details & Apply

As a Postdoctoral Research Fellow, you will work on the development of bioengineered EVs and testing novel LNPs to enhance delivery of oligonucleotides and therapeutic mRNAs.

Most of the research will be conducted using cell lines and animal models. The first part of the work will involve developing stable cell lines for production of EVs engineered to harbor reporter proteins. Uptake of EVs derived from different cells will then be assessed in different recipient cells. The best EV source will then be engineered to contain mRNA or short RNAs and tested for functional delivery in relevant reporter cell lines (the reporter cell lines are already established in the lab). Successful candidate constructs will later be developed to target disease relevant targets first in vitro and later in vivo. In parallel, LNPs will be screened for delivery of splice switching oligonucleotides and mRNA therapeutics. The work will be highly innovative and require extensive knowledge regarding molecular biology techniques, cell culture and the process of making stable cells via lentivirus transduction or transposon transfection, as well as formulation work and downstream characterization of nanoparticles.

The Department of Laboratory Medicine comprises seven divisions and is active across many areas of Laboratory Medicine to promote human health in short and long term. The department collaborates closely with Karolinska Hospital and engages in advanced basic, clinical, and epidemiological research. It is also one of the largest teaching departments at Karolinska Institutet.

The research group of Dr. Ping Chen in the Division of Clinical Chemistry is seeking a postdoctoral fellow with expertise in RNA splicing and computational method development. The Chen lab is interested in developing advanced computational approaches to decipher RNA diversity and its regulatory mechanisms in human metabolic diseases, with the goal of advancing diagnostics and therapeutic strategies. The group works closely with multidisciplinary teams, integrating biobank resources, longitudinal clinical data, and multi-omics technologies with innovative computational and experimental methods. A two-year postdoctoral position will be available starting 1 January 2026 in the Chen lab.

Vi söker en postdoktor till ett kvalitativt forskningsprojekt som syftar till att undersöka erfarenheter, attityder och möjliga hinder för anhörigvårdare med icke europeisk bakgrund att söka stöd och hjälp när de vårdar en person med demenssjukdom i hemmet.

Som postdoktor kommer din anställning att innebära att du är involverad i rekrytering av informanter, kvalitativ datainsamling och databearbetning. Som postdoktor kommer du att förväntas delta i dataanalys samt förberedelse av artikelmanus och andra aktiviteter för att sprida projektets resultat. Du kan också behöva organisera seminarier och stakeholder workshops.

The KIRI postdoctoral fellow will be jointly supervised by Associate Professor Edmund Loh and Associate Professor Lina Davies Forsman. This joint supervision will provide a unique opportunity to combine molecular microbiology with clinical infectious disease research. Through strong mentorship, access to two collaborative research environments, and advanced training programs, the postdoc will develop a broad interdisciplinary skill set. In this KIRI project, Dr. Loh will supervise the postdoc in studying how gene polymorphisms, differential gene and ncRNAs expression could influence antibiotic resistance in Mycobacterium tuberculosis, using molecular techniques such as gene cloning, transcriptomic sequencing, and RNA analysis. Dr. Davies Forsman will supervise the postdoc in understanding clinical aspects of tuberculosis infections and how basic research can be translated into clinical applications.

As a postdoc in this project, you will be part of KIRI, the KI Research Incubator, a unique initiative at KI to build a community for interdisciplinary research and breakthrough discoveries. You will have access to two PI:s that you can meet and interact with to facilitate the research process and increase the synergetic effects. You will also have the opportunity to meet other KIRI postdocs, present your work at scientific events, and take part in KIRI activities. Read more about KIRI here.

The postdoctoral fellow will work with an international research team in an international collaboration to design and conduct research relevant to the research group’s agenda while receiving advanced training to enhance professional skills and research independence. The postdoc’s time will also be devoted to data and database management, analysis, manuscript preparation and career development. The candidate will be asked to collaborate with others, including graduate students, and provide her/his expertise in other projects. There are no teaching requirements but opportunities to teach can be facilitated.