Masaryk University, Czech Republic invites online Application for number of Fully Funded PhD Degree at various Departments. We are providing a list of Fully Funded PhD Programs available at Masaryk University, Czech Republic.
Eligible candidate may Apply as soon as possible.
(01) PhD Degree – Fully Funded
PhD position summary/title: PhD Candidate/Student in effect of lipid asymmetry on membrane protein function
The primary aim is to elucidate the structural and dynamical properties of lipids in asymmetric membranes, particularly their interactions with integral membrane proteins, with an emphasis on bacterial lipid compositions. Initial step will involve determining lipid chain order parameters, bilayer structure, and lipid dynamics. Subsequently, lipid-protein interactions will be assessed, focusing on lipid-induced modulation of enzymatic activity in two bacterial proteins: OmpLA, a β-barrel protein, and GlpG, an α-helical transmembrane protein. The findings will offer key insights into the role of lipid asymmetry in biological membranes and its influence on membrane protein function, with potential applications in the development of lipid-targeted therapeutics and biosensors for pharmaceutical and biotechnological use.
Deadline :31 Dec 2025
(02) PhD Degree – Fully Funded
PhD position summary/title: PhD Candidate: Ribosomal complexes involved in human translation control
Are you passionate about studying human translation control? This is a perfect opportunity for you! Our research project focuses on investigating the structures of ribosomal complexes involved in this fascinating process.
You’ll have access to state-of-the-art cryo-EM instruments at our local core facility, available for regular use. Plus, comprehensive training in cryo-EM techniques will be provided to the successful candidate. Our lab has recently secured substantial third-party funding, including an ERC Starting Grant and an EMBO Installation Grant, so we’re well-equipped to support your research.
We’re seeking a creative, independent, and motivated individual with relevant experience in fields like structural biology, biochemistry, biophysics, or molecular biology. If you have a background in structural biology and translation, we especially encourage you to apply.
Deadline : 30 Sep 2025
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(03) PhD Degree – Fully Funded
PhD position summary/title: PhD Candidate/Student in lipid nanoparticles in drug delivery
We’re excited to announce an open PhD student position in Robert Vacha’s Research Group!
With nearly 10 million lives claimed annually, cancer remains one of the leading causes of mortality worldwide, highlighting the urgent need for more effective treatments. One promising strategy involves mRNA-based cancer immunotherapy vaccines, which require a drug delivery system capable of reliably reaching the cytosol. Developing such delivery systems is challenging: they must ensure cytosolic delivery and therapeutic efficacy while maintaining safety, long-term stability, and compliance with scalable manufacturing standards—including high mRNA loading efficiency and uniform particle size. Current lipid- and polymer-based systems offer distinct advantages, but integrating lessons from both may help develop more effective next-generation carriers. A major limitation remains the incomplete understanding of nanoparticle assembly and disassembly under diverse physiological conditions (e.g., extracellular fluids, endosomal compartments, cytosol).
This project will use coarse-grained molecular simulations, complemented by in-house experimental validation, to gain molecular insights in the controlled system assembly and disassembly. Our goal is to guide the rational design of improved mRNA delivery systems to advance the efficacy of cancer immunotherapy.
Deadline : 31 Dec 2025
(04) PhD Degree – Fully Funded
PhD position summary/title: PhD Candidate/Student in regulation of translation
Understanding the intricate mechanisms regulating ribosome maturation and translation under extreme or stress-induced conditions is vital for uncovering how cells adapt to challenging environments. This project will focus on investigating the molecular mechanisms behind ribosome maturation in bacteria and translation regulation in archaea under such conditions. The ultimate goal is to reveal the adaptation strategies that enable cell survival.
By employing state-of-the-art single-particle cryo-electron microscopy (cryo-EM), the project will provide high-resolution structural insights into ribosomal assembly intermediates, stress-induced translation factors, and archaeal translation machinery under extreme conditions. This research is anticipated to significantly advance our understanding of cellular translation regulation and its role in stress and survival mechanisms.
The research will involve close collaboration with leading experimental teams and will be tailored to the interests and strengths of the candidate. We look forward to discussing this exciting opportunity and the project’s scope further during the interview.
Deadline : 30 Sep 2025
(05) PhD Degree – Fully Funded
PhD position summary/title: Ph.D. Fellowship
We are searching for a highly motivated, pro-active, creative, and independent young scientist for the research topic “Modelling the impacts of soil pollution on soil ecosystem services”. The topic is focused on ecosystem services, soil ecotoxicology, soil contamination, and ecological risk assessment. The work will be focused on metals, pesticides, microplastics, PFAS, and nutrients.
Deadline : 30 Sep 2025
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About Masaryk University, Czech Republic- Official Website
Masaryk University (MU) is the second largest university in the Czech Republic, a member of the Compostela Group and the Utrecht Network. Founded in 1919 in Brno as the second Czech university (after Charles University established in 1348 and Palacký University existent in 1573–1860), it now consists of nine faculties and 35,115 students. It is named after Tomáš Garrigue Masaryk, the first president of an independent Czechoslovakia as well as the leader of the movement for a second Czech university.
In 1960 the university was renamed Jan Evangelista Purkyně University after Jan Evangelista Purkyně, a Czech biologist. In 1990, following the Velvet Revolution it regained its original name. Since 1922, over 171,000 students have graduated from the university.
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