Postdoctoral Fellowship (18) at King’s College London, United Kingdom

We are looking for somebody who has experience with the techniques required for this post, including stereotaxic injections, chemogenetics, histology and molecular biology. Some surgical experience is essential.

Training will be provided in in vivo calcium imaging using our multiphoton imaging setup. The role also includes developing a novel approach for awake imaging, which may involve 8 weeks of training in the US.

If you fulfil our essential criteria and are a dedicated researcher with enthusiasm for high-quality science, teamwork, and effective organisational skills, you will be a great fit for this position.

Your funding will come from the Wellcome Trust and includes financial support for attending career development courses and an annual conference. A relocation allowance is also available for candidates moving from outside London. 

This Post CCT Fellowship is for Neurologists who have completed General Neurology training and want to develop a specialist interest in Neuro-oncology. The post leverages the close relationship between the research interests in oncology and neuroscience offered by King’s College London with the Neuro-oncology service based at King’s College Hospital and Guy’s Hospital.

The Fellowship will be split with 50% time for research and 50% time for clinical care. The objective is to prepare the Neurology trainee to lead neuro-oncology research projects in the future that will improve the diagnosis and management of patients with brain tumours.

The Fellow will undertake a research project(s) which impacts diagnosis and management of brain tumour patients. The research project will be supervised by Dr Gerald Finnerty and will be based in the Department of Clinical Neurosciences, King’s College London, which is on the same campus as King’s College Hospital. The Fellow’s research roles will involve developing and conducting the research project in discussion with their supervisor. We anticipate that the Fellow will Identify sources of funding and will contribute to securing those funds. The Fellow will be expected to write up their research project for publication in academic journal(s) and make presentations at conferences or exhibit work in other appropriate events. Existing research topics range from clinical research e.g. CSF liquid biopsy and stroke in brain tumour patients, through to basic science, such as live human brain tissue to study brain tumours.

Research in the Department of Surgical and Interventional Engineering within the School of Biomedical Engineering and Imaging Sciences focuses on developing robotic systems for minimally invasive surgeries. The primary activity relating to this post is vitreoretinal surgical robotics. The project aims to create micro-precise systems that stably and precisely deliver therapies to the retinal layers over prolonged periods of time.

It is expected that the successful candidates will be enrolled in or hold a degree in engineering, physics, or relevant discipline. Experience in robot materials, design, modelling and prototyping is preferred.

The post holder will be employed within the School Biomedical Engineering and Imaging Sciences in the Faculty of Life Sciences & Medicine at King’s College London. The successful applicant will be mostly based on the St. Thomas’ Hospital campus.

The post of Senior Research Scientist (Digital Health and AI Platform Lead) is a senior role on the EMBRACE study led by Professor Josip Car. This is a research post with both research and operational responsibilities, including delivering against research objectives, providing technical leadership with strategic oversight, digital platform vendor management, and ensuring alignment between the digital platform and research objectives.

The post holder will drive the design, development, and implementation of scalable AI-driven platforms that support translational research, clinical decision support, and patient-centric digital health solutions.  They will work cross-functionally with data scientists, clinical researchers, software engineers, product managers, and external partners to conceptualise and deliver novel AI technologies. This post demands both deep scientific understanding and strong technical leadership, with the ability to navigate complex datasets, ensure model robustness and compliance, and align digital innovation with unmet clinical and healthcare needs.

The Research Scientist in Machine Learning for Wearables will develop predictive deep learning models to assess maternal and partner health and behaviour throughout pregnancy, enabling a holistic understanding of health trajectories and personalised interventions.

The post focuses on analysing multimodal data collected from wearable devices (e.g., heart rate, sleep patterns, physical activity) and voice biomarkers to identify patterns linked to maternal health outcomes. The goal is to support personalised health interventions and contribute to the advancement of precision maternal and early childhood care within the EMBRACE research programme, which is led by Professor Josip Car. 

Multimodal wearable data will be collected from smartwatches/fitness trackers via continuously monitoring physiological metrics, including heart rate, heart rate variability, sleep patterns, physical activity levels, energy expenditure and so forth. They will be analysed to detect patterns and anomalies correlating with known markers of maternal health, including blood pressure, blood glucose, gestational weight gain, sleep and stress levels. In addition, the project will also aim to analyse voice biomarkers to capture unique vocal features that may reflect pregnant women’s physical and mental health risks and conditions. There will also be opportunities to develop research profile, travel for conferences and presentations, as well as contribute to academic publications.

The post holder of Research Scientist (Medical) on the EMBRACE programme led by Professor Josip Car focuses on physical activity interventions during pregnancy.  There remain gaps in evidence and unanswered research questions related to physical activity and exercise during pregnancy spanning physiological, psychological, social, and clinical domains.  This highlights the need for comprehensive interdisciplinary research to understand how to optimise physical activity recommendations. The post holder will contribute to the design, delivery, evaluation, and dissemination of intervention strategies aimed at promoting safe, sustainable physical activity among pregnant individuals.

This post offers an exciting opportunity to work within an interdisciplinary team in maternal health, exercise science, digital health and population health, and to make a real-world impact on clinical practice and public health policy.  The post holder is expected to collaborate with colleagues, present findings at conferences, publish research, and co-supervise project students, ensuring the project’s success and broader scientific impact.

We are looking for a talented and motivated candidate to join us as a Marie Skłodowska-Curie Actions (MSCA) Doctoral Candidate (fixed-term 3 years, 100%FTE) to develop computational models of the neonatal brain. The successful candidate will work on the intersection of neuroscience and new computational methods, combining mathematical and biophysical models with state-of-the-art diffusion and functional MRI data, in typically and atypically developing populations through the lifespan.

Applications are invited for the position of Post-Doctoral Research Associate in the Department of Diabetes at King’s College London (KCL), working in the laboratories of Prof Gavin Bewick.

The role focuses on delivering a high-impact translational research programme that dissects how neuropeptide Y5 receptor (Y5R) signalling in islet-resident immune cells can be harnessed to prevent or delay Type 1 diabetes, ultimately generating a compelling mechanistic and pre-clinical evidence base to support future clinical development. The post holder will drive studies that define how Y5R activation reprogrammes resident macrophages and other islet immune subsets towards a restorative, anti-inflammatory phenotype, identify key signalling pathways and biomarkers of efficacy, and test whether Y5R agonism can block pathogenic macrophage and T cell trafficking to, and destruction of, islets in both mouse and human model systems. A central purpose of the role is to bridge fundamental mechanistic immunology with translational proof-of-concept, using cutting-edge omics, advanced imaging, and in vivo models to de-risk Y5R agonists as a novel disease-modifying strategy for Type 1 diabetes.​

The researcher will be responsible to the Principal Investigator, Prof Gavin Bewick, who holds overall scientific and technical accountability for the project, and will work closely with co-applicants and collaborators including experts in macrophage biology, multi-omic and regulatory network analysis, and clinical translation of investigational therapies in Type 1 diabetes. Day-to-day, the post holder will be responsible for planning, executing, analysing and interpreting complex experiments spanning bulk and single-cell RNA sequencing of resident islet immune populations, macrophage functional assays (innate sensing, phagocytosis, antigen presentation, polarization, cytokine and growth factor secretion), and transwell-based invasion and migration platforms using reformed mouse and human islets. The role carries responsibility for ensuring experimental quality and reproducibility, coordinating sample acquisition from human islet biobanks and animal colonies, and integrating multi-modal datasets in collaboration with bioinformatics partners to define Y5R-dependent regulatory networks and therapeutic pathways.

We are seeking an ambitious and motivated MR physicist to join our multidisciplinary team in a pioneering MRC funded project exploring the early development of activity in the brain in newborn infants using ultra-high field (7 Telsa) MRI.

The primary focus of this role will be to perform methods development work in the highly specialized area of ultrahigh field magnetic resonance imaging of infants. Performing imaging studies with the infant population introduces many specific challenges which may be further enhanced at ultrahigh field including but not limited to: safety considerations, accounting for age specific tissue properties, and addressing motion artefacts. Resolving these will require complex problem solving through integrating, cutting-edge methodology and working closely as part of a team including clinicians, neuroscientists, engineers and computer scientists, all of whom are engaged with studying the early developing brain with previously unprecedented precision.

This post-doctoral position is funded by a Lupus Research Alliance Mechanistic Award held jointly by Dr Deborah Cunninghame Graham (PI) and Prof Timothy Vyse (co-PI), within the Department of Medical and Molecular Genetics at King’s College London.

OX40 (encoded by TNFRSF4) and its exclusive receptor OX40L (encoded by TNFSF4), play key roles in pathogenesis of the autoimmune disease, Systemic Lupus Erythematosus (SLE).  The interaction between these two TNF-superfamily members on the surface of activated T and B cells leads to a strong co-stimulatory signal.   SLE genetic analyses support the conjecture that increased activity of the OX40/OX40L axis drives the disease.  We have shown that serum levels of soluble OX40 and its ligand are elevated in many lupus patients compared with healthy controls.  Several therapeutics have been developed that block OX40-OX40L.  This proposal seeks to: (1) explore the clinical utility and biology of soluble OX40 and OX40L; and (2) to define a subset of patients who would most likely benefit from OX40-OX40L blocking therapeutics and hence support re-purposing of the reagents already available.

The project forms part of an international programme of work defining the roles of OX40 and OX40L in SLE, including juvenile-onset disease.  The post-holder will work within a multi-disciplinary environment, including PhD students as well as master’s and undergraduate students undertaking research projects in the wider group.  There will be close interaction between wet-lab scientists and their analytical counterparts.  The post-doc will be expected to contribute the findings their work with other members of the group, thereby contributing to the overall biological interpretation.  The post-holder will take the lead in liaising with researchers in external collaborating groups to harmonise the genetic, transcriptomic, proteomic, clinical and experimental data for the study cohort.  They will take responsibility for optimising the MSD multiplex immunoassay to measure the levels of serum proteins in the study samples and contribute to the analysis methods to assess their value as prognostic biomarkers.  The post-holder will also perform pQTL analyses and use mendelian randomisation methods to seek evidence for the causality.  They will also set up and analyse multi-parameter flow cytometry panels to assess how immune cell activation correlates with serum levels of OX40/L and to identify the likely cellular source of serum OX40 or serum OX40L.

The postholder will join exciting new studies in the group. These include testing the synaptic hypothesis of psychosis and the role of excitation-inhibition balance in psychotic disorders and testing how the first non-D2 antipsychotics work. The studies involve in vivo imaging with cutting edge PET and fMRI techniques and clinical trials.

The postholders will be responsible for recruitment and clinical assessment of participants with psychosis, including clinical rating scales and delivering a high level of care to research participants. They will be responsible for organising and acquiring imaging and other measures and producing scoping literature reviews.

The postholders will be responsible for ensuring high quality research governance across projects, helping to analyse, interpret and publish the results of projects, as well as helping to support students who will be working on the projects.

The postholders will be responsible for maintaining accurate records within a database that can be shared with members of the wider research team. They are also responsible for organising and overseeing weekly case and control tracking meetings, as well as quarterly steering group meetings.

The postholders will be responsible for ensuring effective collaborative relationships with other research worders on the project, as well as with local clinical services and researchers on other related projects.

The postdoc will investigate the biology of the junctional epithelium, a stem cell compartment in the oral mucosa, that replenishes the tissues around the tooth. this to understand this unique and essential structure. We aim to follow the development of the junctional epithelium and establishment of its stem cells niche. We will then investigate how this tissue is impacted in case of disease and detachment from the tooth.

The postdoc will be responsible for planning experiments in conjunction with Prof Tucker, performing experiments, analysing data and mouse colony management.

At the Label-free Bioimaging Laboratory at King’s College London, a prestigious European Research Council (ERC) Consolidator Grant–funded opportunity is available for a Postdoctoral Research Associate (PDRA) with strong expertise in fibre optics and medical technologies.

The appointed PDRA will play a central role within the ERC-funded research programme, contributing both technical leadership and conceptual innovation. As a core member of the Label-free Bioimaging Laboratory, the PDRA will be responsible for delivering high-quality, internationally competitive research outputs, while providing intellectual input into experimental design, technology development, and translational strategy. Working closely with the Principal Investigator and collaborators, the PDRA will lead the design, development, optimisation, and validation of advanced fibre-optic and optical imaging platforms.

Within the scope of the ERC project, the PDRA will drive forward the development of next-generation label-free optical technologies aimed at enabling real-time, in vivo cancer diagnosis. This will involve micromanufacturing and integrating advancing device engineering for clinical compatibility, and translating laboratory prototypes toward practical biomedical application. The role will require independent problem-solving, cross-disciplinary collaboration, and a highly proactive approach to innovation, with opportunities to supervise students and contribute to grant writing and research planning.

The successful applicant will join a vibrant and highly collaborative multidisciplinary team within a fully equipped (and new refurbished), state-of-the-art optics laboratory at King’s College London. The group works at the intersection of optical microscopy, fiber-optics disease characterisation, biomedical engineering, and translational biophotonics, offering an excellent environment that bridges fundamental photonics research with impactful clinical translation.

Dr Andrea Serio & Dr. Sarah Marzi are seeking a highly motivated and skilled Research Associate at the UK Dementia Research Institute (UK DRI) at King’s College London.

This opportunity would suit a bright, talented, highly motivated, and ambitious individual to who will play a key role working on a project focused on the development of a multiomic platform to investigate early molecular signatures of ALS pathology in human motor neurons using a novel system developed in the Serio lab.

The successful candidate will have a demonstrable track record and experience bioinformatics and data analysis, particularly -omics approaches in biology and a keen interest in neuroscience and neurodegeneration. Demonstrable experience dealing with iPSC-derived cultures and data in the context of neurobiology or neurodegeneration studies is desirable.

The successful candidate will have at least a PhD in a relevant field and postdoctoral experience in a research lab with projects, preferably focused on neurobiology or neurodegeneration.

The post holder will work with other team members across the Serio and Marzi lab to generate stem cell-based models of ALS using a novel cell culture platform developed in the Serio lab for the study of axons, and will lead on the multiomic analysis to compare different genotypes.

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Postdoctoral Research Associate

Deadline : 26 April 2026.

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