19 Postdoctoral Fellowship at King’s College London, United Kingdom

We are advertising for a one-year Post-Doc positions at King’s College London to work with Prof. Osvaldo Simeone on reliable AI, with topics including distributed conformal prediction and Bayesian learning. The post will be based in the King’s Communications, Learning & Information Processing lab, at the Centre for Intelligent Information Processing Systems within the Department of Engineering.  

We are seeking a highly motivated and skilled Research Associate to join our dynamic and interdisciplinary team, contributing to cutting-edge research at the intersection of cancer biology, artificial intelligence, and biomedical data science. This role offers an exciting opportunity to work at the forefront of cancer research, developing computational approaches to analyze complex biological data and uncover insights that can improve patient outcomes.

The ideal candidate will have a PhD (or be near completion) in Bioinformatics, Computational Biology, Computer Science, Artificial Intelligence, or a related field. Candidates with extensive research or industrial experience will also be considered. You will collaborate closely with both computational and experimental researchers, bridging the gap between AI-driven analysis and biological discovery. Your primary responsibilities will include developing and implementing bioinformatics pipelines, analyzing high-dimensional datasets—including whole slide histopathology images and multi-omics data—and integrating diverse data sources to identify biomarkers and therapeutic targets.

We are seeking a highly motivated postdoctoral researcher with expertise in statistics (preferably longitudinal modelling) and an interest in developmental cognitive neuroscience or psychology to join the research team led by Dr Divyangana Rakesh. The lab is seeking someone who is passionate about developmental cognitive neuroscience and enjoys analysing data and solving statistical problems to support a project funded by the MRC. The postdoctoral researcher will lead a research program focused on studying links between socioeconomic disadvantage, brain development, and cognitive and academic outcomes using big, openly available datasets, under the supervision of Dr Rakesh.

This role will provide you with the freedom to develop new and creative ideas, methodologies, and/or approaches to challenging and societally important questions. In addition to leading the project, you will be supported in finding a research area that interests you, encouraged to develop a research programme of your own, and apply for independent funding. The postdoctoral researcher will also have teaching opportunities if this is of interest.

The Nott group is looking for a skilled and motivated postdoctoral researcher. This project will combine structural and cellular approaches to study the conformations, interactions, and catalytic activity of membraneless organelle proteins. 

Applicants should hold (or be close to completing) a PhD in a relevant area of biological, chemical, or physical science and be able to lead an interdisciplinary project. Expertise in biomolecular NMR is highly desirable. Applicants should have a strong interest in disordered proteins, excellent communication skills, and the ability to write for scientific publication. 

We are seeking a highly motivated Research Fellow or Senior Research Fellow in Health Coaching to lead the development and evaluation of health coaching interventions for university students. This role involves designing, implementing, and assessing the effectiveness of a structured health coaching program where students will be trained as health coaches to support individuals with chronic conditions, such as hypertension, improving their lifestyle behaviours, including physical activity and healthy nutrition. The ideal candidate will have expertise in behavioural health interventions, coaching methodologies, and research evaluation, with a strong background in public health, psychology, health sciences, or a related field.

This role is ideal for a passionate researcher eager to bridge behavioural science and practical intervention design, with a focus on improving student training in health coaching and enhancing chronic disease management. If you have the drive to make a meaningful impact, we encourage you to apply!

We are seeking an outstanding and motivated candidate to join our research team. The successful candidate will contribute to cutting-edge research on digital health interventions, focusing on the role of health apps to improve population health outcomes and exploring how the NHS can better adopt and integrate health apps into its digital infrastructure. A key aspect of the role will be to investigate strategies for enhancing the impact of the NHS App, MyChart and their associated digital services.

A new position is available for an experienced post-doctoral Research Associate in Computational Genomics in the UK Dementia Research Institute (UK DRI) research group led by Dr Sarah Marzi.

You will lead one or more projects characterising the epigenome and transcriptome of brain cell types in the context of neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease and ALS.  You will be based at King’s College London under the supervision of Dr Sarah Marzi (https://www.kcl.ac.uk/people/sarah-marzi). You will contribute to the design and analysis of large-scale ‘omics datasets with a primary focus on analysis of the epigenome and chromatin architecture to address major research questions relevant to AD.

This opportunity would suit a bright, talented, highly motivated, and ambitious individual to lead one or more computational projects exploring the transcriptome and epigenome of brain cell types relevant to disease. The post holder will use next-generation sequencing data from patient-derived brain tissue and stem cell model systems to identify signalling pathways and transcription factors dysregulated in brain diseases with a focus on Alzheimer’s disease. You will use genomic datasets that may include (long reads) RNA-seq, ChIP-seq, CUT&Tag, ATAC-seq and single cell/nuclei datasets. These studies will help to guide the functional interpretation of disease risk variants and environmental risk factors for aging-related brain disorders such as Alzheimer’s disease and Parkinson’s disease.

This department has a focus on fundamental questions regarding human physiological function and adaptation in health and disease and occupies an important nexus between basic biomedical sciences, clinical and applied research. It comprises four interlinking research groupings operating under an overarching strategy focused on furthering understanding of integrative human physiology. Our research encompasses a unique whole-body systems through to stem cell approaches which is aimed at gaining insight into factors affecting human health, disease, biological ageing and exercise, as well as performance in unique and extreme environments. We are committed to integrative and translational research which is facilitated by collaborations with other research groupings within King’s College London, King’s Health Partners, industry and the military.

The successful candidate will develop a research programme in human cardiorespiratory control, leading to the submission of applications for a personal fellowship.  The candidate will also make contributions to teaching. The post holder will be embedded in a highly interdisciplinary and collaborative research environment, where 75% of research is rated 4* (world leading; UoA24 REF2021). The appointee will join an interactive group of investigators with expertise across a whole range of research groupings: Aerospace & Environmental Physiology & Medicine, Respiratory Physiology & Medicine, Skeletal and Cardiac Muscle: Form & Function and Neural Control of Human Movement. Our department is responsible for the delivery of post graduate programmes in Human & Applied Physiology (MSc), Aerospace Medicine (Diploma / MSc) as well as the BSc in Sport & Exercise Medical Sciences.

We are seeking a dedicated Research Associate in Population Health Management to work closely between King’s Population Health Institute and King’s Health Partners on population health initiatives across South East London. This role will involve conducting research, analysing healthcare data, and contributing to the design and implementation of evidence-based strategies to improve health outcomes at the population level. The ideal candidate will have expertise in population health research, health data analytics, and population health strategies.

This role is ideal for a researcher passionate about health equity, data-driven decision-making, and real-world population health impact. If you have the expertise and enthusiasm to drive meaningful change, we encourage you to apply!

This is for two full-time posts relating to funding received from the Economic and Social Research Council (ESRC) funded Productivity Institute.  Each Postdoctoral Research Associate will work full-time for 12 months on complementary projects focusing on original data collection and qualitative research. Project 1 will investigate companies and organisations in the agri-tech sector. Project 2 will investigate companies and organisations in the creative industries (broadcasting and games).

The research investigates three questions: i) How do organisations develop skills and knowledge in response to the pervasive nature of digital technologies (including generative technologies such as AI)? ii) How do firms handle the generative potential of digital technologies to develop unique capabilities and competitive advantages? iii) How do they reconcile the need for efficiency gains and strategic innovation while integrating digital technologies into new and/or existing organizational practices and routines?

Unlike in hematologic malignancies, the efficacy of chimeric antigen receptor (CAR) modified T cells in solid tumors such as breast cancer has been very limited.  Oncolytic viruses (OVs) encoding a variety of transgenes have been evaluated as therapeutic tools to increase the efficacy of CAR-modified T cells within the typically immunosuppressive solid tumour microenvironment (TME). Using fully systemic delivery of OVs and CAR T in fully immunocompetent mouse models, we have defined a new mechanism by which OVs can potentiate CAR T efficacy against solid tumours.  Our novel approach shows that stimulation of the native T cell receptor (TCR) in the CAR T cells against either OV-derived viral antigens, or against OV-encoded tumour antigens, gives rise to enhanced proliferative and functional properties and distinct memory phenotypes of the CAR T. In vivo expansion of dual specific (DS) CAR T (specific for both CAR target antigen through the CAR and viral/tumour antigen through the TCR) was leveraged by in vitro pre-loading with oncolytic Vesicular Stomatitis virus (VSV) or reovirus.  This allowed for a further in vivo expansion/re-activation by homologous boosting, which led to high cure rates in murine models of subcutaneous melanoma and intra-cranial High-Grade Glioma (HGG) (Evgin et al., 2022 Science Translational Medicine).  We now plan to test this strategy pre-clinically in the treatment of breast cancer leading directly to the generation of IND-enabling data to translate DS CAR T cell therapy into a fully systemic protocol for CAR T/OV combination therapy against breast tumours which, critically, does not require direct access to the tumour for administration.

The purpose of this role is to develop new mass spectrometry techniques that can be used to enable users of the facility to make new measurements of material sampled using the SEISMIC facility.  Analysis of single-cells using mass spectrometry is challenging, and yet analysis of sub-cellular compartments is the next frontier, possible at SEISMIC and in high demand by biologists.  Kings have recently made a significant investment in mass spectrometry instrumentation, to enable the development of this approach by capillary sampling and mass spectrometry. 

The post holder will work with the SEISMIC team and KCL core facilities team to develop new mass spectrometry techniques that can be used to analyse capillary sampled cells and their sub-cellular compartments.  They will be encouraged to present their work at national and international conferences, and work with users of the facility to demonstrate proof of concept applications.  They will be encouraged to submit applications for funding, for example for fellowships to support their future career. 

We are seeking a post-doctoral researcher with expertise in evidence synthesis methods, and interests in automation/use of AI to join the Solace-AI team. The successful candidate will lead the development of next-generation evidence synthesis methods at the intersection of AI and systematic review science to tackle urgent climate-health challenges across the globe.

Solace-AI is a Wellcome Trust-funded initiative developing cutting-edge AI technology to transform how we synthesize and deliver research evidence during climate-related health emergencies. By automating the creation of rapid, scientifically-rigorous evidence syntheses, this groundbreaking project aims to provide decision-makers with timely, locally relevant research—particularly focusing on historically underserved communities affected by extreme weather events.

You will work closely with computer science teams and world-leading experts in AI, public health, and climate science across Africa, Europe, and North America to implement evidence synthesis methods in automated systems capable of handling complex research documents. This includes developing novel evaluation frameworks to assess AI performance in evidence synthesis tasks, while ensuring all outputs remain rigorous, relevant, and actionable for decision-makers and humanitarian organisations.

The King’s College London British Heart Foundation (BHF) Centre of Research Excellence is designed to nurture interdisciplinary collaborations and bench-to-bedside projects in cardiovascular research (www.kcl.ac.uk/scms/bhf-centre).

We are seeking a Postdoctoral Research Associate to join the Faculty of Cardiovascular Medicine & Sciences, the core constituent of the BHF Centre.

The applicant will work on a Diabetes UK-funded project aiming to uncover novel events in diabetic microangiopathy that can be targeted pharmacologically to restore the function of the microvasculature. Microangiopathy is a major complication in diabetes mellitus with a pronounced impact on microvascular perfusion, vessel rarefaction and tissue ischemia. Using human blood vessel organoids (BVOs) we recently demonstrated that they capture key aspects of the microvasculature and respond rapidly to metabolic rewiring (Romeo et al Nat Commun 2023  10.1038/s41467-023-41326-2). In this project, the successful applicant will utilize diabetic patient-derived BVOs to establish a functional screening platform that will enable personalized therapeutic approaches. This pipeline will serve as a personalized system to test existing and new medications to identify effective drugs for each diabetic patient.

 

(18) Postdoctoral Fellowship Position

Postdoc Fellowship Position summary/title: Research Associate

Deadline : 02 March 2025.

View details & Apply

 

The McTernan Group aims to apply recent breakthroughs in artificial molecular machines and metal-organic capsules in biologically relevant settings. We work with rotaxanes, catenanes and capsules to synthesise functional architectures, creating de novo catalytic enzyme analogues, artificial cellular receptors, and generating targeted drug delivery vehicles. We work both in basic science, and translational applications.

This the successful candidate for this 24-month role will lead our chemical biology research programme; designing and conducting experiments, liaising with world-leading STPs at the Francis Crick Institute, developing and deploying assays, training junior researchers, and liaising with CROs. They will take the lead on assaying the biological activity of the numerous therapeutic molecules developed in our laboratory, and help guide their successful optimisation, working closely with chemists across our research portfolio.